Katharine Korunes

PhD Student

University Program in Genetics and Genomics
Duke University
E-mail: katharine.korunes@duke.edu
B.S., University of Georgia, 2013


Research Interests

I am interested in a wide variety of evolutionary questions, and I particularly enjoy thinking about recombination and how it contributes to genome evolution.  Meiotic recombination shuffles combinations of alleles, and absence of recombination can create blocks of linkage-disequilibrium.  Thus, understanding meiotic recombination is critical for understanding how genetic diversity is created and maintained.  Currently, my primary research project is focused on understanding how recombination is affected by chromosomal inversions.  Inversions suppress recombination, but we don't fully understand how and to what extent.  Though single-crossover products are prevented within inversion heterozygotes, non-crossover gene conversion (and double crossovers) can still occur.  To better understand the strength of the gene flux barrier imposed by inversions, I am studying the frequency and distribution of non-crossover gene conversion in inversion heterozygotes using the species pair Drosophila pseudoobscura and D. persimilis.

Link to video of talk at 2016 TAGC conference


Publications

Korunes, K. L., and M. A. F. Noor. 2017. Gene conversion and linkage: Effects on genome evolution and speciation. Molecular Ecology, 26: 351-364. doi:10.1111/mec.13736

Mittleman, B. E., B. Manzano-Winkler, J. B. Hall, K. L. Korunes, and M. A. F. Noor. 2017. The large X-effect on secondary sexual characters and the genetics of variation in sex comb tooth number in Drosophila subobscura. Ecology and Evolution, 7: 533-540. doi:10.1002/ece3.2634

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