Publications

  

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Scientific Papers and Articles

    1. Hamed Esfandiari, Ali Efatizadeh, Azadeh Doozandeh, Mehdi Yaseri, Nils A Loewen. Factors Associated with Lamina Cribrosa Displacement After Trabeculectomy Measured by Optical Coherence Tomography in Advanced Primary Open Angle Glaucoma. Submitted. Researchgate preprint. February 15, 2018
      1. Esfandiari H, Hassanpour K, Yaseri M and Loewen NA. Extended pharmacological miosis is superfluous after glaucoma angle surgery: A retrospective study. F1000Research 2018, 7:178 (doi: 10.12688/f1000research.13756.1)
        1. Hamed Esfandiari; Tarek Shazly, Priyal Shah; Kiana Hassanpour; Pooya Torkian, Mehdi Yaseri, Nils Loewen. Impact of Same-Session Trabectome Surgery on Ahmed Glaucoma Valve Outcomes. Researchgate preprint. February 1, 2018.
        2. Hamed Esfandiari; Tarek Shazly, Priyal Shah; Kiana Hassanpour; Pooya Torkian, Mehdi Yaseri, Nils Loewen. Impact of Same-Session Trabectome Surgery on Ahmed Glaucoma Valve Outcomes. Researchgate preprint. February 1, 2018.
        3. Chao Wang, Yalong Dang, Priyal Shah, Susannah Waxman, Ralitsa T. Loewen, Hamed Esfandiari, Nils A. Loewen. In vitro and ex vivo characterization of K-115, a hypotensive Rho-kinase inhibitor, in a pigmentary glaucoma model. Researchgate preprint. February 1, 2018.
        4. Chao Wang, Yalong Dang, Priyal Shah, Susannah Waxman, Ralitsa T. Loewen, Hamed Esfandiari, Nils A. Loewen. Goniotome ab interno trabeculectomy reduces IOP in an ex vivo model of pigmentary glaucoma. Researchgate preprint. January 26, 2018.
        5. Yalong Dang, Chao Wang, Priyal Shah, Susannah Waxman, Ralitsa T. Loewen, Ying Hong, Hamed Esfandiari, Nils A. Loewen. An evaluation of three different ab interno trabeculectomy procedures to increase the outflow facility in a porcine eye perfusion model. Researchgate preprint. January 25, 2018
        6. Yalong Dang, Chao Wang, Priyal Shah, Susannah Waxman, Ralitsa T. Loewen, Nils A. Loewen. Ocular hypotension, actin stress fiber disruption and phagocytosis increase by RKI-1447, a Rho-kinase inhibitor. Researchgate preprint. January 25, 2018.
        7. Dang Y, Wang X, Cen Y, Hong Y, Huang P, Loewen N, Zhang C. Two-year outcomes of ab interno trabeculectomy with the Trabectome for Chinese primary open angle glaucoma: a retrospective multicenter study. Researchgate preprint. January 2018.
        8. Zhang X, Dastiridou A, Francis BA, Tan O, Varma R, Greenfield DS, Schuman JS, Huang D, Advanced Imaging for Glaucoma Study Group. Comparison of Glaucoma Progression Detection by Optical Coherence Tomography and Visual Field. Am J Ophthalmol. 2017 Dec;184:63–74. PMID: 28964806
        9. Wang C, Dang Y, Loewen R, Waxman S, Xia X, Loewen N. Impact of Pigment Dispersion on Trabecular Meshwork Cells. Researchgate preprint. DOI 10.13140/RG.2.2.33476.32648. 2017 December 1.
        10. Esfandiari H, Hassanpour K, Knowlton P, Shazly T, Yaseri M, Loewen NA. Trabectome Surgery Combined with Baerveldt Glaucoma Implantation Negates Tube Fenestration. Researchgate preprint. 2017 November 2017.
        11. Esfandiari H, Amouhashemi N, Yaseri M, Torkian P, Pakravan M, Jadidi K, Loewen NA. Low Iris and Anterior Chamber Volume Associated with Deepening after Laser Peripheral Iridotomy in Primary Angle Closure Suspects. Researchgate preprint. 2017 November 2017.
        12. Esfandiari H, Loewen NA, Hassanpour K, Fatourechi A, Yazdani S, Yaseri M, Pakravan M. Fuchs Heterochromic Iridocyclitis-Associated Glaucoma: A Retrospective Comparison of Primary Ahmed Glaucoma Valve implantation and Trabeculectomy with MMC. Researchgate preprint. 2017 Oct 27. Link.
        13. Waxman S, Loewen RT, Dang Y, Watkins SC, Watson AM, Loewen NA. High-Resolution, Three Dimensional Reconstruction of the Outflow Tract Demonstrates Segmental Differences in Cleared Eyes. Researchgate preprint 2017 Sep 29. Link.  
        14. Dang, Y; Waxman, S; Wang, C; Loewen R; Loewen, NA. Intraocular pressure elevation precedes a phagocytosis decline in a model of pigmentary glaucoma. August 12, 2017. Preprint doi: 10.13140/RG.2.2.14205.87522
        15. Dang, Y; Waxman, S; Wang, C; Loewen R; Sun, M; Loewen, NA. Trabecular meshwork failure in a model of pigmentary glaucoma. March 18, 2017. Preprint doi: 10.1101/118448
        16. Shazly, T; Waxman, S; Kola, S; Kaplowitz, KB; Brown EN; Loewen NA. Similar Performance of Trabectome and Ahmed Glaucoma Devices in a Propensity Score Matched Comparison. Preprint March 6, 2017. DOI: 10.13140/RG.2.2.30723.50727
        17. Esfandiari, H; Pakravan, M; Loewen, NA; Yaseri, M. The predictive Value of Early Postoperative IOP and Bleb Morphology in Mitomycin-C Augmented Trabeculectomy. Preprint March 5, 2017. DOI: 10.13140/RG.2.2.12492.21122
        18. Shazly, T; Kostanyan, T; Kaplowitz, KB; Wang, SZ; Kola, S; Brown, EN; Loewen, NA. Longer-Term Baerveldt to Trabectome Glaucoma Surgery Comparison using Propensity Score Matching. Graefe’s Archiv. In press. Preprint doi: 10.13140/RG.2.2.29376.74242
        19. Dang, Y; Waxman, S; Wang, C; Jensen, A; Loewen R; Bilonick, R; Loewen, NA. Freeze-thaw decellularization of the trabecular meshwork in an ex vivo eye perfusion model. PeerJ. 2017 Aug 14;5:e3629. doi: 10.7717/peerj.3629.
        20. Wang C, Dang Y, Waxman S, Xia X, Weinreb RN, Loewen NA. Angle stability and outflow in dual blade ab interno trabeculectomy with active versus passive chamber management. PLoS One. 2017 May 9;12(5):e0177238. PMID: 28486513
        21. Dang Y, Waxman S, Wang C, Parikh HA, Bussel II, Loewen RT, Xia X, Lathrop KL, Bilonick RA, Loewen NA. Rapid learning curve assessment in an ex vivo training system for microincisional glaucoma surgery. Sci Rep. 2017 May 9;7(1):1605. PMID: 28487512
        22. Roy P, Loewen RT, Dang Y, Parikh HA, Bussel I, Loewen NA. Stratification of phaco-trabectome surgery results using a glaucoma severity index in a retrospective analysis. BMC Ophthalmol. 2017;17:30.
        23. Fallano, K; Bussel, II; Kagemann, L; Lathrop, KL; Loewen, NA. Training strategies and review of ab interno trabeculectomy with the trabectome. f1000research.com/articles/6-67/v1.
        24. Dang, Y; Loewen NA. Commentary: The CyPass, a Novel Supraciliary Implant for Open-Angle Glaucoma. Yan ke xue bao (Eye Science). September 2016.
        25. Parikh HA, Loewen RT, Roy P, Schuman JS, Lathrop KL, Loewen NA. Differential Canalograms Detect Outflow Changes from Trabecular Micro-Bypass Stents and Ab Interno Trabeculectomy. Sci. Rep. Nature Publishing Group; 2016;6:34705.
        26. Loewen N, Francis BA,  Hong B, Dustin L, Kaplowitz K, Kinast R, Bacharach J, Radhakrishnan S, Iwach A, Rudavska L, Ichhpujani P, Katz LJ. Repeatability of selective laser trabeculoplasty for open-angle glaucoma. BMC Ophthalmol. 2016 Jul 28;16:128. doi: 10.1186/s12886-016-0299-9.
        27. Dang Y, Kaplowitz K, Parikh HA, Roy P, Loewen RT, Francis BA, Loewen NA. Steroid-induced glaucoma treated with trabecular ablation in a matched comparison to primary open angle glaucoma. Clin Experiment Ophthalmol. June 2016. doi:10.1111/ceo.12796.
        28. Dang Y, Roy P, Bussel II, Loewen RT, Parikh HA, Loewen NA. Combined analysis of trabectome and phaco-trabectome outcomes by glaucoma severity. F1000Res. 2016;5:762.
        29. Loewen RT, Brown EN, Scott G, Parikh H, Schuman JS, Loewen NA. Quantification of Focal Outflow Enhancement Using Differential Canalograms. Invest Ophthalmol Vis Sci. 2016;57(6):2831-2838.
        30. Neiweem AE, Bussel II, Schuman JS, Brown EN, Loewen NA. Glaucoma Surgery Calculator: Limited Additive Effect of Phacoemulsification on Intraocular Pressure in Ab Interno Trabeculectomy. PLoS One. 2016;11(4):e0153585.
        31. Loewen RT, Roy P, Parikh H, Dang Y, Schuman JS, Loewen N.A. Impact of a Glaucoma Severity Index on Results of Trabectome Surgery: Larger Pressure Reduction in More Severe Glaucoma. PLoS One. 2016;11(3):e0151926.
        32. Loewen RT ,Brown EN, Roy P, Schuman JS, Sigal IA, Loewen N.A. Regionally Discrete Aqueous Humor Outflow Quantification Using Fluorescein Canalograms. PLoS One. 2016;11(3):e0151754.
        33. Kaplowitz, K., Wang, S., Bilonick, R., Oatts, J.T., Grippo, T., Loewen, N.A. Randomized Controlled Comparison of Titanium-Sapphire versus Standard Q-switched Nd:YAG Laser Trabeculoplasty. J Glaucoma. 2016 Jul;25(7):e663-7.
        34. Polat JK, Loewen NA. Combined phacoemulsification and trabectome for treatment of glaucoma. Surv Ophthalmol. May 2016. doi:10.1016/j.survophthal.2016.03.012.
        35. Kaplowitz K, Bussel I.I., Honkanen R., Schuman J.S., Loewen N.A.  Review and Meta-Analysis of Ab-Interno Trabeculectomy Outcomes. Br J Ophthalmol. 2016 May;100(5):594-600. doi: 10.1136/bjophthalmol-2015-307131. Review. PMID: 26733487
        36. Dang Y, Loewen R, Parikh HA, Roy P, Loewen N.A.  Gene Transfer to the Outflow Tract. Exp Eye Res. 2016 Apr 27. pii: S0014-4835(16)30096-3. doi: 10.1016/j.exer.2016.04.023.
        37. Loewen RT, Roy P, Park DB, Jensen A, Scott G, Cohen-Karni D, Fautsch MP, Schuman JS, Loewen N.A. A Porcine Anterior Segment Perfusion and Transduction Model with Direct Visualization of the Trabecular Meshwork. Invest Ophthalmol Vis Sci. 2016 Mar 1;57(3):1338-44. doi: 10.1167/iovs.15-18125.
        38. Zhang X, Francis BA, Dastiridou A, Chopra V, Tan O, Varma R, Greenfield DS, Schuman JS, Huang D; Advanced Imaging for Glaucoma Study Group. Longitudinal and Cross-Sectional Analyses of Age Effects on Retinal Nerve Fiber Layer and Ganglion Cell Complex Thickness by Fourier-Domain OCT. Transl Vis Sci Technol. 2016 Mar 4;5(2):1. eCollection 2016 Mar. PubMed PMID: 26966637; PubMed Central PMCID: PMC4782827.
        39. Zhang X, Loewen N, Tan O, Greenfield DS, Schuman JS, Varma R, Huang D; Advanced Imaging for Glaucoma Study Group. Predicting Development of Glaucomatous Visual Field Conversion Using Baseline Fourier-Domain Optical Coherence Tomography. Am J Ophthalmol. 2016 Mar;163:29-37. doi: 10.1016/j.ajo.2015.11.029.
        40. Akil H, Chopra V, Huang A, Loewen N, Noguchi J, Francis BA. Clinical Results of Ab Interno Trabeculotomy Using the Trabectome in Patients with Pigmentary Glaucoma compared to Primary Open Angle Glaucoma.  Clin Experiment Ophthalmol. 2016 Mar 6. doi: 10.1111/ceo.12737.
        41. Parikh HA, Bussel II, Schuman JS, Brown EN, Loewen NA. Coarsened Exact Matching of Phaco-Trabectome to Trabectome in Phakic Patients: Lack of Additional Pressure Reduction from Phacoemulsification. PLoS One. 2016 Feb 19;11(2):e0149384.
        42. Richter GM, Zhang X, Tan O, Francis BA, Chopra V, Greenfield DS, Varma R, Schuman JS, Huang D; Advanced Imaging for Glaucoma Study Group. Regression Analysis of Optical Coherence Tomography Disc Variables for Glaucoma Diagnosis. J Glaucoma. 2016 Feb 19. [Epub ahead of print] PubMed PMID: 26900833.
        43. Oatts JT, Wang X, Loewen NA. Effect of alpha-2-agonist premedication on intraocular pressure after selective laser trabeculoplasty. Indian J Ophthalmol. 2015 Dec;63(12):891-4.
        44. Kaplowitz K, Blizzard S, Blizzard DJ, Nwogu E, Hamill CE, Weinreb RN, Mohsenin V, Loewen NA. Time Spent in Lateral Sleep Position and Asymmetry in Glaucoma. Invest Ophthalmol Vis Sci. 2015;56(6):3869-3874.
        45. Loewen, N.A., Zhang, X, Tan O., Greenfield D.S., Schuman J.S., Varma R., Huang D. Combining measurements from three anatomical areas for glaucoma diagnosis using Fourier-domain optical coherence tomography. Br J Ophthalmol. 2015. doi:10.1136/bjophthalmol-2014-305907.
        46. Iverson SM, Feuer WJ, Shi W, Greenfield DS; Advanced Imaging for Glaucoma Study Group. Frequency of abnormal retinal nerve fibre layer and ganglion cell layer SDOCT scans in healthy eyes and glaucoma suspects in a prospective longitudinal study. Br J Ophthalmol. 2014 Jul;98(7):920-5. PubMed PMID: 24627246.
        47. Le PV, Zhang X, Francis BA, Varma R, Greenfield DS, Schuman JS, Loewen N, Huang D, Advanced Imaging for Glaucoma Study Group. Advanced Imaging for Glaucoma Study: Design, Baseline Characteristics, and Inter-Site Comparison. Am. J. Ophthalmol. 2014. doi:10.1016/j.ajo.2014.11.010.
        48. Bussel II, Kaplowitz K, Schuman JS, Loewen NA, Trabectome Study Group. Outcomes of ab interno trabeculectomy with the trabectome by degree of angle opening. Br. J. Ophthalmol. 2014. doi:10.1136/bjophthalmol-2014-305577.
        49. Bussel II, Kaplowitz K, Schuman JS, Loewen NA, Trabectome Study Group. Outcomes of ab interno trabeculectomy with the trabectome after failed trabeculectomy. Br. J. Ophthalmol. 2014. doi:10.1136/bjophthalmol-2013-304717.
        50. Minckler D, Mosaed S, Francis B, Loewen N, Weinreb RN. Clinical results of ab interno trabeculotomy using the Trabectome for open-angle glaucoma: the Mayo clinic series in Rochester, Minnesota. Am. J. Ophthalmol. 2014;157(6):1325-1326.
        51. Kaplowitz K, Schuman JS, Loewen NA. Techniques and outcomes of minimally invasive trabecular ablation and bypass surgery. Br. J. Ophthalmol. 2014;98(5):579-585.
        52. Zhang Z, Dhaliwal AS, Tseng H, Kim JD, Schuman JS, Weinreb RN, Loewen NA. Outflow tract ablation using a conditionally cytotoxic feline immunodeficiency viral vector. Invest. Ophthalmol. Vis. Sci. 2014;55(2):935-940.
        53. Kaplowitz K, Abazari A, Honkanen R, Loewen N. iStent surgery as an option for mild to moderate glaucoma. Expert Rev. Ophthalmol. 2014;9(1):11-16.
        54. Kaplowitz K., Schuman J.S., Loewen N.A. Techniques and Outcomes of Minimally-Invasive Trabecular Ablation and Bypass Surgery. Br J Ophthal. 97.10 (2013): 1228-1229.
        55. Loewen N.A., Schuman JS. There has to be a better way: evolution of internal filtration glaucoma surgeries. Br J Ophthalmol. 2013 Oct;97(10):1228-9.
        56. Oatts J.T., Zhang Z., Tseng H.P., Shields M.B., Sinard J.H., Loewen N.A. In Vitro and In Vivo Comparison of Two Suprachoroidal Shunts. Invest Ophthalmol Vis Sci 54.8 (2013): 5416-5423.
        57. Marcus I., Salchow D.J., Sophie L. Leung, Elaine J. Zhou, Tsai J.C., Loewen N.A. Academic Associate Program Impact on Clinical Study Enrollment in an Academic Ophthalmology Practice. J Academic Ophthalmol. 2013;6(1):69-75
        58. Sigler EJ, Mascarenhas KG, Tsai JC, Loewen NA. Clinicopathologic Correlation of Disc and Peripapillary Region Using SD-OCT. Optom Vis Sci. 2013. Jan;90(1):84-93.
        59. Ni N, Tsai JC, Shields MB, Loewen NA. Elevation of intraocular pressure in glaucoma patients after automated visual field testing. J Glaucoma. 2012 Dec;21(9):590-5.
        60. Saenz DT, Barraza R, Loewen N, Teo W, Poeschla EM. Feline immunodeficiency virus-based lentiviral vectors. Cold Spring Harb Protoc. 2012 Jan 1;2012(1):71-6.
        61. Saenz DT, Barraza R, Loewen N, Teo W, Poeschla EM. Titration of feline immunodeficiency virus-based lentiviral vector preparations. Cold Spring Harb Protoc. 2012 Jan 1;2012(1):126-8.
        62. Saenz DT, Barraza R, Loewen N, Teo W, Poeschla EM. Production and harvest of feline immunodeficiency virus-based lentiviral vector from cells grown in T75 tissue-culture flasks. Cold Spring Harb Protoc. 2012 Jan 1;2012(1):124-5.
        63. Saenz DT, Barraza R, Loewen N, Teo W, Poeschla EM. Production, harvest, and concentration of feline immunodeficiency virus-based lentiviral vector from cells grown in CF10 or CF2 devices. Cold Spring Harb Protoc. 2012 Jan 1;2012(1):118-23.
        64.  George M., Tsai J.C., Loewen, N.A. Bilateral Irreversible Severe Vision Loss from Cosmetic Iris Implants. Am J Ophthalmol. 2011 May;151(5):872-875.
        65. Guedes G., Tsai J.C., Loewen N. Glaucoma and Aging. Curr Aging Sci. 2011 Jan 14.
        66. Loewen N. Vision Loss after Trabeculectomy in Advanced Glaucoma. Glaucoma Today. Nov 2009.
        67. Loewen N., Liu J.H.K., Weinreb R.N. Increased 24-Hour Variation of Human Intraocular Pressure with Short Axial Length. Invest Ophthalmol Vis Sci. 2009 Sep 9.
        68. Loewen N., Chen J., Dudley V.J., Sarthy V.P., Mathura J.R., Jr. Genomic response of hypoxic Müller cells involves the very low density lipoprotein receptor as part of an angiogenic network. Exp Eye Res. 2009 May;88(5):928-37.
        69. Barraza R.A., Rasmussen C.A., Loewen N., Cameron D.J., Gabelt B.T., Teo W., Kaufman P.L., Poeschla E.M. Prolonged transgene expression with lentiviral vectors in the aqueous humor outflow pathway of nonhuman primates. Hum Gene Ther. 2009 Mar;20(3):191-200.
        70. Ezzat M.K., Howell K.G., Bahler C.K., Beito T.G., Loewen N., Poeschla E.M., Fautsch M.P. Characterization of Monoclonal Antibodies against the Glaucoma-Associated Protein Myocilin. Exp Eye Res. 2008 Oct;87(4):376-84.
        71. Khare P., Loewen N., Teo W., Barraza R., Saenz D.T., Johnson D.H., Poeschla E.M. Durable, Safe, Multi-gene Lentiviral Vector Expression for Over Two Years in Feline Trabecular Meshwork. Mol Ther. 2008 Jan;16(1):97-106.
        72. Fautsch MP, Bahler CK, Vrabel AM, Howell KG, Loewen N., Teo WL, Poeschla EM, Johnson DH. Perfusion of HIS-tagged eukaryotic myocilin increases outflow resistance in human anterior segments in the presence of aqueous humor. Invest Ophthalmol Vis Sci. 2006 Jan;47(1):213-21.
        73. Loewen N., Poeschla E.M. Lentiviral Vectors. Adv Biochem Eng Biotechnol. 2005;99:169-91.
        74. Loewen N., Fautsch M.P., Teo W., Bahler C.K., Johnson D.H., Poeschla E.M. Long-term, targeted genetic modification of the aqueous humor outflow tract coupled with non-invasive imaging of gene expression in vivo. Invest Ophthalmol Vis Sci. 2004 Sep;45(9):3091-98.
        75. Loewen N., Leske D.A., Cameron J.D., Chen Y., Teo W., Fautsch M.P, Poeschla E.M., Holmes J.M. Long-term retinal transgene expression with FIV versus adenoviral vectors. Mol Vis. 2004 Apr 13;10:272-80.
        76. Saenz D.T., Loewen N., Peretz M., Whitwam T., Howell K.G., Holmes J.M., Good M., Poeschla E.M. Unintegrated lentiviral DNA persistence and accessibility to expression in nondividing cells: analysis with class I integrase mutants. J. Virol. 2004 Mar;78(6):2906-20.
        77. Loewen N., Leske D.A., Chen Y., Teo W., Saenz D.T., Peretz M., Holmes J.M., Poeschla E.M. Comparison of wild type and class I integrase mutant-FIV vectors in retina demonstrates sustained expression of integrated transgenes in retinal pigment epithelium. J Gene Med. 2003 Dec;5(12):1009-17.
        78. Loewen N., Bahler C., Teo W., Whitwam T., Peretz M., Xu R., Fautsch M., Johnson D.J., Poeschla E.M. Preservation of aqueous outflow facility after second-generation FIV vector-mediated expression of marker genes in anterior segments of human eyes. Invest Ophthalmol Vis Sci. 2002 Dec;43(12):3686-90.
        79. Loewen N., Fautsch M.P., Peretz M., Bahler C.K., Cameron J.D., Johnson D.H., Poeschla E.M. Genetic modification of human trabecular meshwork with lentiviral vectors. Hum Gene Ther. 2001 Nov 20; 12(17): 2109-19.
        80. Barry J.C., Loewen N. The use of cycloplegic agents. Results of a 1999 survey of German-speaking centers for pediatric ophthalmology and strabology. Klin Monatsbl Augenheilkd 2001 Jan; 218(1): 26-30.
        81. Loewen N., Barry J.C. The use of cycloplegic agents. Results of a 1999 survey of German-speaking centers for pediatric ophthalmology and strabology. Strabismus 2000 Jun; 8(2):91-9.

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        1. Other Peer-Reviewed Publications
        2. Parikh H., Bussel I., Loewen. N.A. Ab interno trabeculectomy demonstrates positive outcomes, even in patients with narrow angles. Ophthalmology Times Europe. September 2015.
                                                                                                                          1. Hardik A. Parikh, Pritha Roy, Amar Dhaliwal,  Kevin B. Kaplowitz,  Nils A. Loewen. Trabectome Patient Selection, Preparation, Technique, Management, and Outcomes. US Ophthalmic Review. October 2015.
                                                                                                                          2. Kaplowitz K., Bussel I., Schuman J.S., Loewen N.A. Expanding Indications of Ab-Interno Trabeculectomy. Ophthalmology Times Europe. December 2014.
                                                                                                                          3. Polat J., Loewen N.A. Trabectome: Ab Interno Trabeculectomy. EyeWiki September 2014.
                                                                                                                          4. Brown E., Loewen N.A. Treatment Pathways in Glaucoma and Cataract Care. Ocular Surgery News, March 2014.
                                                                                                                          5. Lagouros E., Loewen N.A. The Right Microscope for Demanding Surgery. Ocular Surgery News, February 2014.
                                                                                                                          6. Loewen N.A. Large referral center explores efficacy of Trabectome-mediated ab interno trabeculectomy. Ocular Surgery News, January 2014.
                                                                                                                          7. K Kaplowitz, A Abazari, R Honkanen and N Loewen. iStent Surgery as an Option for Mild to Moderate Glaucoma. Expert Rev Ophthalmol. 2013 Dec 18.
                                                                                                                          8. Kim J, Loewen N.A. International Glaucoma Review 15-1, 2013 “Optimizing gene transfer to conventional outflow cells in living mouse eyes.”
                                                                                                                          9. Loewen N.A. Opinion Piece: We Must Do Better, Acquire Excellent MIGS Skills. International Glaucoma Review. March 2013
                                                                                                                          10. Loewen N.A. The Suprachoroidal Space in Glaucoma Surgery. Refractive Eyecare. July 1012.
                                                                                                                          11. Kaplowitz K., Loewen N.A. Trabectome Surgery: A Minimally-Invasive Glaucoma Procedure. Publication by the Glaucoma Research Foundation. May 17, 2012
                                                                                                                          12. Loewen N.A. Combined Glaucoma and Cataract Procedures. In Print.
                                                                                                                          13. Kaplowitz K.B., Loewen N.A. Surgical Management of the Loose Lens. US Ophthalmic Review, 2013;6(2):105–8.
                                                                                                                          14. Kaplowitz K.B., Loewen N.A. High IOP in Traumatic Hyphema. Glaucoma Today. May 2012.
                                                                                                                          15. Thomas, S., Loewen N.A. The Literature Column. Glaucoma Today. Apr 2011.
                                                                                                                          16. Loewen N.A. Xalatan going generic. Glaucoma Today. Apr 2011.
                                                                                                                          17. Loewen N.A. Ophthalmology Management. June 2011. “Advantages of FORUM Implementation”
                                                                                                                          18. Ahrlich K.G., Loewen N.A. Glaucoma Diagnostic Technologies. Cataract & Refractive Surgery Today Europe, May 2011.
                                                                                                                          19. Loewen N.A. Ocular Surgery News. September 2010. "Glaucoma Medications: Not a First Choice".
                                                                                                                          20. Loewen N.A. International Glaucoma Review 12-3, 2010 "Gene delivery of erythropoietin protects retinal ganglion cells in DBA/2J glaucomatous mice. Sullivan T.A, Geisert E.E, Rex T.S.Molecular Therapy 2010; 18: S171"
                                                                                                                          21. Loewen N.A. International Glaucoma Review 12-2, 2010 "Adenoviral Gene Transfer of Active Human Transforming Growth Factor-Beta2 Elevates Intraocular Pressure and Reduces Outflow Facility in Rodent Eyes."
                                                                                                                          22. Loewen N.A. International Glaucoma Review 12-1, 2010 "Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys. Buie LK, Rasmussen CA, Porterfield EC, Ramgolam VS, Choi VW, Markovic-Plese S, Samulski RJ, Kaufman PL, Borrás T. Invest Ophthalmol Vis Sci. 2010; 51: 236-248."
                                                                                                                          23. Loewen N.A. International Glaucoma Review 11-3, 2010 "Long-term outcomes of needle revision of trabeculectomy blebs with mitomycin C and 5-fluorouracil: a comparative safety and efficacy report. Anand N, Khan A. J Glaucoma 2009; 18: 513-520"
                                                                                                                          24. Loewen N. Ophthalmic Surgical Procedures. J Glaucoma. 2009 Oct 22.
                                                                                                                          25. Loewen N. Tsai J.C. Managing a Failing Bleb. Glaucoma Today. October 2009.
                                                                                                                          26. Loewen N. Poor office visit follow-up compliance could affect glaucoma surgical success. Ocular Surgery News. July 2010.
                                                                                                                          27. Loewen N., Schanzlin D.J., Vizzeri G., Weinreb R.N. Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) in a Patient with Trabeculectomy. Glaucoma Today. 2008 Oct:15-18.
                                                                                                                          28. Loewen N., Weinreb R.N. Book review: Curbside Consultation in Glaucoma. SLACK Incorporated, 2008 J. Glaucoma. November 2008.

                                                                                                                                                                                    Book Chapters

                                                                                                                                                                                    1. Kaplowitz K., Bussel I., Loewen N.A. Minimally Invasive Glaucoma Surgery: the Science and the Practice. Chapter 7: Trabeculectomy by Internal Approach: Trabectome. Eds Francis B. & Sarkisian S. Thieme, 2015.
                                                                                                                                                                                    2. Kaplowitz, K., Loewen, N. A. Trabectome-Mediated Ab Interno Trabeculectomy for Secondary Glaucoma or as a Secondary Procedure (eds. Aref, A. A. & Varma, R.) 51–73 (Springer, 2014).
                                                                                                                                                                                    3. Kaplowitz K., Bussel I., Loewen N.A.  Minimally Invasive and Nonpenetrating Glaucoma Surgery in Ophthalmology: Expert Consult: Online and Print (eds. Yanoff, M. & Duker, J. S.) 1133–1146 (Elsevier - Health Sciences Division, 2013).
                                                                                                                                                                                    4. Kaplowitz K., Loewen N.A. Minimally Invasive Glaucoma Surgery: Trabeculectomy Ab Interno. Surgical Innovations in Glaucoma. (eds. Samples, John R. & Ahmed, Iqbal Ike K.) Springer New York, 2014. 175-186.
                                                                                                                                                                                    5. Loewen N.A., Tanna A.P. Role of Intraocular Pressure in the Diagnosis and Treatment of Glaucoma. In: Schacknow PN, Samples JR The Glaucoma Book: A Practical, Evidence-Based Approach to Patient Care. 2013. 2nd Edition. Springer. 35-50.
                                                                                                                                                                                    6. Loewen N.A., Tanna A.P. Role of Intraocular Pressure in the Diagnosis and Treatment of Glaucoma. In: Schacknow PN, Samples JR The Glaucoma Book: A Practical, Evidence-Based Approach to Patient Care. First. Springer; 2010:1016.
                                                                                                                                                                                    7. Saenz D.T., Barraza R., Loewen N., Teo W., Poeschla E., 2005, Production and Use of Feline Immunodeficiency Virus (FIV)-Based Lentiviral Vectors, In: Rossi, J., Friedman, T. (Eds.) Gene Transfer: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 57-73
                                                                                                                                                                                    8. Loewen N., Barraza R., Whitwam T., Saenz, D.T., Kemler I., Poeschla E.M. FIV Vectors. In M. Federico: Lentiviral gene engineering protocols. Humana Press, USA, 2003: 251-273.

                                                                                                                                                                                          Patents

                                                                                                                                                                                          1. A highly engineered FIV vector system useful for delivering genes to cells (co-inventor, patent application 9/2004, Mayo Medical Venture # MMV-04-133).
                                                                                                                                                                                          2. An Auto-Regulated, Doxycycline-Inducible FIV-Based Lentiviral Vector (co-inventor, patent application 6/2002, Mayo Medical Venture # MMV-02-098).

                                                                                                                                                                                          Invited Talks and Lectures

                                                                                                                                                                                              1. Trabectome Surgery: Techniques and Technology. International Glaucoma Meeting 2015. University of Lanzhou, China.
                                                                                                                                                                                              2. Outcomes in Expanded Indications. International Glaucoma Meeting 2015. University of Lanzhou, China.
                                                                                                                                                                                              3. Trabeculoplasty. International Glaucoma Meeting 2015. University of Lanzhou, China.
                                                                                                                                                                                              4. Outflow Engineering. Grand Rounds Speaker University of Mainz, Germany.
                                                                                                                                                                                              5. Restoring Outflow. Vision Restoration Conference 2015. University of Pittsburgh 2015.
                                                                                                                                                                                              6. Introduction to Trabectome Surgery: Technique and Outcomes. 2015 Sanmenxia, China.
                                                                                                                                                                                              7. Trabectome Surgery: Update on Technique and New Range of Indications. Asian Pacific Association of Ophthalmology 2015. Guangzhou, China.
                                                                                                                                                                                              8. Laser Trabeculoplasty as 1st line of treatment for glaucomas with open angle. Kansas City Society of Ophthalmology 2015.
                                                                                                                                                                                              9. Ab Interno Trabeculectomy: Techniques and range of Indications. Kansas City Society of Ophthalmology 2015
                                                                                                                                                                                              10. Ab Interno Approach to Schlemm’s Canal. American Academy of Ophthalmology. Chicago 2014.
                                                                                                                                                                                              11. Trabeculoplasty as First Line of Treatment in POAG. South Florida Ophthalmology Meeting. September 2014. Tampa, FL.
                                                                                                                                                                                              12. Anterior Chamber Anatomy and Glaucoma. Vision Core Lecture Series. University of Pittsburgh. 2014.
                                                                                                                                                                                              13. Glaucoma Surgery. University of Pittsburgh Lecture Series 2014.
                                                                                                                                                                                              14. Bioengineering Outflow. South Florida Ophthalmology Meeting. September 2014. Tampa, FL.
                                                                                                                                                                                              15. Ab Interno Trabeculectomy from Hypertension to Advanced Glaucoma. September 2014. Tampa, FL.
                                                                                                                                                                                              16. Towards Outflow Tract Regeneration. Regenerative Ophthalmology Meeting 2014. University of Pittsburgh.
                                                                                                                                                                                              17. Trabectome Course at the Annual Meeting of the Deutsche Ophthalmo-Chirurgen 2014. Nuremberg, Germany.
                                                                                                                                                                                              18. Trabectome Course and Wet Lab at the American Academy of Ophthalmology meeting 2013. New Orleans.
                                                                                                                                                                                              19. Live Surgery Course and Wet Lab at the 23rd Midwest Glaucoma Symposium, University of Pittsburgh, School of Medicine. 2013.
                                                                                                                                                                                              20. Key Steps in Trabectome Surgery. 23rd Midwest Glaucoma Symposium, University of Pittsburgh, School of Medicine. 2013.
                                                                                                                                                                                              21. Key Steps in Trabectome Surgery: Lectures and Wet Labs. 2nd Innovations in Glaucoma Surgery. St. Louis University 2013.
                                                                                                                                                                                              22. Ab Interno Trabeculectomy. World Glaucoma Congress 2013, Vancouver, Canada.
                                                                                                                                                                                              23. Bioengineering of Trabecular Meshwork. 2013 Vision Restoration: Regenerative Medicine in Ophthalmology. University of Pittsburgh, PA.
                                                                                                                                                                                              24. Reverse Engineering of the Outflow Tract. 2013 McGowan Institute Biomedical Engineering Retreat. Nemacolin, PA.
                                                                                                                                                                                              25. Rethinking Glaucoma Surgery. University California San Diego Ophthalmology Update 2013, San Diego, CA.
                                                                                                                                                                                              26. Putting Phaco-Trabectome into Perspective. Hawaiian Eye 2013.
                                                                                                                                                                                              27. Key Steps in Trabectome Surgery. Hawaiian Eye 2013.
                                                                                                                                                                                              28. Laser Trabeculoplasty Techniques and Pre- and Postoperative Management. Hawaiian Eye 2013.
                                                                                                                                                                                              29. Phaco-Trabectome Techniques - Video. Hawaiian Eye 2013.
                                                                                                                                                                                              30. Glaucoma Drainage Device Discussion. Hawaiian Eye 2013.
                                                                                                                                                                                              31. Minimally Invasive Glaucoma Surgery. Hawaiian Eye 2013.
                                                                                                                                                                                              32. Trabectome Skill Transfer Course. AAO 2012. Chicago, IL.
                                                                                                                                                                                              33. Trabectome Wetlab. Association for Research in Vision and Ophthalmology 2012. Bascom Palmer, Florida, FL.
                                                                                                                                                                                              34. Trabectome Update. American Glaucoma Society. February 2012. Manhattan, New York.
                                                                                                                                                                                              35. Trabectome Wetlab. American Glaucoma Society. February 2012. Manhattan, New York.
                                                                                                                                                                                              36. Trabeculoplasty as First Line of Treatment for Open Angle Glaucoma. American Academy of Ophthalmology. October 2011. Orlando, Florida.
                                                                                                                                                                                              37. Trabectome as a Primary Surgery. American Academy of Ophthalmology. October 2011. Orlando, Florida.
                                                                                                                                                                                              38. Integration of Visual Field and Optic Nerve Examination Data with Electronic Medical Record Systems. American Academy of Ophthalmology. October 2011. Orlando, Florida.
                                                                                                                                                                                              39. Managing the Loose Lens. World Glaucoma Congress June 2011. Paris, France.
                                                                                                                                                                                              40. Trabeculectomy: How I Do It. World Glaucoma Congress June 2011. Paris, France.
                                                                                                                                                                                              41. Annual Harvard School of Medicine Intensive Cataract Surgery Training Course. May 7-8, 2011. Boston, MA
                                                                                                                                                                                              42. The Role of Ocular Blood Flow. American Society of Cataract and Refractive Surgery 2011.
                                                                                                                                                                                              43. New Glaucoma Surgeries. American Society of Cataract and Refractive Surgery 2011.
                                                                                                                                                                                              44. Approach to Cataract Surgery in Hypotony. American Glaucoma Society 2011.
                                                                                                                                                                                              45. Glaucoma Surgery Related Emergencies. New York, NY. Yale Ophthalmic Emergencies Symposium 2010.
                                                                                                                                                                                              46. 24-Hour IOP Variations and Refractive Error. International Society for Eye Research. Montreal, Canada, Biennial Meeting 2010.
                                                                                                                                                                                              47. Intracameral and Intravitreal Agents. American Society of Cataract and Refractive Surgery. Boston, MA, Annual Meeting 2010.
                                                                                                                                                                                              48. Glaucoma Surgery, Postoperative Care and Emergencies. Joint Commission on Allied Health Personnel in Ophthalmology, American Society of Cataract and Refractive Surgery. Boston, MA, Annual Meeting 2010.
                                                                                                                                                                                              49. Small Pupil Surgery. American Glaucoma Association. Naples, FL, Annual Meeting 2010.

                                                                                                                                                                                                                                                                                                                Abstracts

                                                                                                                                                                                                                                                                                                                1. Hardik Parikh,BS, Igor I. Bussel,MD, Joel S. Schuman,MD, Nils A. Loewen, MD, PhD. Matched Comparison of Phaco-Trabectome to Trabectome in Phakic Patients. American Glaucoma Society Meeting 2015.
                                                                                                                                                                                                                                                                                                                2. Ralitsa Loewen, Pritha Roy, Hardik Parikh, Yalong Dang, Joel Schuman, Nils Loewen. Impact of Relative Glaucoma Severity on Results of Trabectome Surgery.  American Glaucoma Society Meeting 2015.
                                                                                                                                                                                                                                                                                                                3. Pritha Roy, MD, Ralitsa Loewen, MD, Hardik Parikh, BS, Yalong Dang, MD, Joel Schuman, MD, Nils Loewen, MD, PhD. Stratification of Results of Trabectome with Phacoemulsification by Glaucoma Severity: Larger IOP Reduction in More Advanced Glaucoma. American Glaucoma Society Meeting 2015.
                                                                                                                                                                                                                                                                                                                4. Neiweem, A.,1* Bussel, I.I.,2* Schuman, J.S.,2 Brown, E.N.,2, 3 Loewen, N.A.2✝. Trabectome Surgery Calculator: Additive Effect from Combining Phacoemulsification with Trabectome in a Matched Comparison to Sequential Trabectome in Pseudophakic Eyes. American Glaucoma Society Meeting 2015.
                                                                                                                                                                                                                                                                                                                5. Yalong Dang, Hardik Parikh, Pritha Roy, Igor Bussel, Ralitsa Loewen, Nils Loewen. Trabectome-Mediated Ab Interno Trabeculectomy for Steroid-Induced Glaucoma. American Glaucoma Society Meeting 2015.
                                                                                                                                                                                                                                                                                                                6. Loewen N. Outflow Modification. Nantucket Glaucoma Meeting 2015.
                                                                                                                                                                                                                                                                                                                7. Loewen R., Brown E., Sengupta P., Kola S., Schuman J.S., Loewen N.A. Semi-Quantitative Measurements and Live Outflow Imaging In Porcine Eyes. Vision Restoration Conference. University of Pittsburgh 2015.
                                                                                                                                                                                                                                                                                                                8. Loewen R., Sengupta P., Cohen-Karni D., Kola S., Ladley R., Dhaliwal A., Mandell J., Espandar L., Schuman J.S., Loewen N.A. Trabecular Meshwork Engineering and Live Tracking in Perfused Porcine Anterior Segments. Association for Research in Vision and Ophthalmology 2015.
                                                                                                                                                                                                                                                                                                                9. Loewen R., Sengupta P., Kola S., Schuman J.S., Loewen N.A. Live Outflow Imaging In Porcine Eyes. Association for Research in Vision and Ophthalmology 2015.
                                                                                                                                                                                                                                                                                                                10. Loewen R., Sengupta P., Cohen-Karni D., Kola S., Ladley R., Dhaliwal A., Mandell J., Espandar L., Schuman J.S., Loewen N.A. Trabecular Meshwork Engineering and Live Tracking in Perfused Porcine Anterior Segments. Association for Research in Vision and Ophthalmology 2015.
                                                                                                                                                                                                                                                                                                                11. Steven Wang, Eric Brown, Kevin Kaplowitz, Sushma Kola, Julia Polat, Joel S. Schuman, Nils A. Loewen. Comparison of Trabectome Ab Interno Trabeculectomy to Baerveldt Glaucoma Implants using Propensity Score Matching.  Association for Research in Vision and Ophthalmology 2015.
                                                                                                                                                                                                                                                                                                                12. Sushma Kola, Eric Brown, Kevin Kaplowitz, Steven Wang, Julia Polat, Joel S. Schuman, Nils A. Loewen, Case-Matched Intraocular Pressure Results of Trabectome Ab Interno Trabeculectomy versus Ahmed Glaucoma Implant. Association for Research in Vision and Ophthalmology 2015.
                                                                                                                                                                                                                                                                                                                13. Loewen N.A., Bussel I, Kaplowitz K. Meta-Analysis of Trabeculectomy Ab-Interno Outcomes. American Glaucoma Society Meeting 2015.
                                                                                                                                                                                                                                                                                                                14. Xinbo Zhang , Nils A Loewen, Ou Tan PHD, Brian A Francis MD, Rohit Varma MD MPH, David S Greenfield MD, Joel S Schuman MD. Predicting Glaucomatous Visual Field Damage With Fourier Domain OCT in the Advanced Imaging for Glaucoma Study. American Academy of Ophthalmology 2014. Chicago.
                                                                                                                                                                                                                                                                                                                15. John E. Legarreta, Ian P. Conner, Nils A. Loewen, Kimberly V. Miller, Jeremy Wingard. The Utility of iPhone-based Imaging for Tele-ophthalmology in a Triage Capacity for Emergency Room Consultations. Association for Research in Vision and Ophthalmology 2014. Poster.
                                                                                                                                                                                                                                                                                                                16. Sushma K., Lagouros, E, Kaplowitz, K, Davis R., Schuman J.S., Loewen N.A. Comparison of Trabectome Ab Interno Trabeculectomy to Baerveldt and Ahmed Glaucoma Implants. Association for Research in Vision and Ophthalmology 2014. Poster.
                                                                                                                                                                                                                                                                                                                17. Dhaliwal A., Kola S., Kim J, Zhang Z, Tseng H, Schuman J.S., Weinreb R.N., Loewen N.A. A Conditionally Cytotoxic Viral Vector for Trabecular Meshwork Ablation. Association for Research in Vision and Ophthalmology 2014. Presentation.
                                                                                                                                                                                                                                                                                                                18. Loewen R., Lagouros E., Loewen N.A. Trabectome Ab Interno Trabeculectomy in Highly Complex Glaucomas. Association for Research in Vision and Ophthalmology 2014. Poster.
                                                                                                                                                                                                                                                                                                                19. Kaplowitz K., Bussel I., Loewen N.A. Degree of Angle Opening not Related to Outcome in Phaco-Trabectome or Trabectome Surgery. American Glaucoma Society Meeting, Washington D.C, 2014. Poster.
                                                                                                                                                                                                                                                                                                                20. Constance Okeke, Eydie Miller-Ellis, Nils Loewen. Factors Associated with Successful Outcomes in Trabectome Only Surgery. American Glaucoma Society Meeting, Washington D.C, 2014. Poster.
                                                                                                                                                                                                                                                                                                                21. Kim J, Dhaliwal A, Zhang Z, Tseng H, Weinreb R.N., Loewen N.A. Lack of Inflammation in Outflow Tract Ablation using a Conditionally Cytotoxic Feline Immunodeficiency Viral Vector. 2013 Research Retreat Ophthalmology. University of Pittsburgh, PA. Poster
                                                                                                                                                                                                                                                                                                                22. Zhang X, Loewen N.A.,  Francis B, Huang D, Chopra V, Greenfield D, Parrish R, Varma R, Schuman JS. Regression Analysis of OCT Disc Variables for Glaucoma Diagnosis. American Academy of Ophthalmology. New Orleans, 2013. Talk.
                                                                                                                                                                                                                                                                                                                23. Bussel I., Loewen N.A. Update on Trabectome Outcomes in POAG and PXG. Deutsche Ophthalmologische Gesellschaft Meeting 2013. Berlin, Germany. Talk.
                                                                                                                                                                                                                                                                                                                24. Bussel I., Loewen N.A. Subgroup Analysis of Trabectome after Failed Trabeculectomy. Deutsche Ophthalmologische Gesellschaft Meeting 2013. Berlin, Germany. Poster.
                                                                                                                                                                                                                                                                                                                25. Zhang Z, Tseng H., Weinreb R.N., Loewen N.A. Vector-Mediated Trabecular Meshwork Ablation In Vivo. Deutsche Ophthalmologische Gesellschaft Meeting 2013. Berlin, Germany. Talk.
                                                                                                                                                                                                                                                                                                                26. Kaplowitz K., Bussel I., Loewen N.A. Trabectome Study Group. 1-Year Outcomes for Trabectome after Failed Trabeculectomy. World Glaucoma Congress 2013. Vancouver, Canada. Talk.
                                                                                                                                                                                                                                                                                                                27. Dhaliwal, A, Kim J, Zhang Z, Tseng H, Weinreb R.N., Loewen N.A. Outflow Tract Ablation using a Conditionally Cytotoxic Feline Immunodeficiency Viral Vector. 2013 Vision Restoration: Regenerative Medicine in Ophthalmology. University of Pittsburgh, PA. Poster.
                                                                                                                                                                                                                                                                                                                28. Kaplowitz K., Chen X., Loewen N.A. Two Year Results of 180° Trabectome Ablation. American Glaucoma Society 2013. San Francisco, CA. Poster.
                                                                                                                                                                                                                                                                                                                29. Oatts J., Kaplowitz K., Loewen N.A. Post-Procedure Intraocular Pressure of Titanium-Sapphire Laser Compared to Standard Selective Trabeculoplasty. American Glaucoma Society 2013. San Francisco, CA. Poster.
                                                                                                                                                                                                                                                                                                                30. Tseng H., Zhang Z., Oatts J., Loewen N.A. In Vitro Biocompatibility Assay of Suprachoroidal Glaucoma Shunts Indicates Vulnerability to Fibrosis In Vivo. Albany Medical College Medical Student Investigation Event. Albany Medical College 2012. Albany, NY. Poster.
                                                                                                                                                                                                                                                                                                                31. Oatts J., Kaplowitz K., Patel N., Loewen N.A. Postoperative Intraocular Pressure After Selective Laser Trabeculoplasty Not Affected by Alpha-2-Agonist Premedication. American Glaucoma Society 2012. New York, NY. Poster.
                                                                                                                                                                                                                                                                                                                32. Kaplowitz K., Wang D.E., Tsai T.C., Loewen N.A. Use of Intraoperative MMC and Postoperative 5FU with Glaucoma Drainage Devices. American Glaucoma Society 2012. New York, NY. Poster.
                                                                                                                                                                                                                                                                                                                33. Chen X., Kaplowitz K., Loewen N.A. Trabectome Results in Eyes with Low Preoperative IOP. Association for Research in Vision in Ophthalmology 2012. Fort Lauderdale, Florida, USA. Poster.
                                                                                                                                                                                                                                                                                                                34. Marcus I., Tsai J.C., Salchow D.J., Loewen N.A. Academic Associate Program Impact on Clinical Study Enrollment in an Academic Ophthalmology Practice. Association for Research in Vision and Ophthalmology 2012. Fort Lauderdale, Florida, USA. Poster.
                                                                                                                                                                                                                                                                                                                35. Oatts J.T., Sinard J.H., Loewen. N.A. Fibrosis and IOP Differences of Two Suprachoroidal Shunts. Association for Research in Vision in Ophthalmology 2012. Fort Lauderdale, Florida, USA. Poster.
                                                                                                                                                                                                                                                                                                                36. Zhang Z., Tseng H., Weinreb R.N., Loewen N.A. Ablation Of Trabecular Meshwork Cells with a Conditionally Cytotoxic FIV Vector. Association for Research in Vision in Ophthalmology 2012. Fort Lauderdale, Florida, USA. Poster.
                                                                                                                                                                                                                                                                                                                37. Nwogu E., Thomas S., Hamill C., Marcus I., Loewen N.A. Visual Field Asymmetry and Sleep Position in Primary Open Angle Glaucoma. Association for Research in Vision in Ophthalmology 2012. Fort Lauderdale, Florida, USA. Poster.
                                                                                                                                                                                                                                                                                                                38. Thomas S; Hamill CE; Blizzard DJ; Marcus IZ; Loewen N.A. Open Angle Glaucoma Asymmetric Visual Field Loss and Sleep Position. Connecticut Society of Eye Physicians Annual Scientific Education Program. June 10, 2011. Plantsville, CT. Poster.
                                                                                                                                                                                                                                                                                                                39. Thomas S., Hamill C.E., Marcus I.Z., Ahrlich K.G., Loewen N.A. Visual Field Asymmetry And Sleep Position In Low Pressure Glaucoma. Association for Research in Vision in Ophthalmology 2011. Fort Lauderdale, Florida, USA. Poster.
                                                                                                                                                                                                                                                                                                                40. Thomas S., Hamill C.E., Marcus I.Z., Loewen N.A. Primary Open Angle Glaucoma Asymmetry and Sleep Position. American Academy of Ophthalmology 2011. Orlando, Florida. Poster.
                                                                                                                                                                                                                                                                                                                41. Tsai JC, Loewen NA. Isolated Check Visual Evoked Potential (icVEP) for Visual Function Assessment in Glaucoma. American Academy of Ophthalmology 2011. Orlando, Florida. Talk.
                                                                                                                                                                                                                                                                                                                42. Ni N., Tsai J.C., Shields M.B., Loewen N.A. Transient Elevations of Intraocular Pressure in Glaucoma Patients after Automated Visual Field Testing. American Academy of Ophthalmology 2010. San Francisco, California. Poster.
                                                                                                                                                                                                                                                                                                                43. Loewen N., Weinreb R.N., Liu, J.H.K. High Body Mass Index Associated with Increased Goldmann IOP but Normal Pneumatonometry IOP. Association for Research in Vision in Ophthalmology 2009. Fort Lauderdale, Florida, USA. Poster.
                                                                                                                                                                                                                                                                                                                44. Feng L., Li W., Loewen N., Pinto H.L., Hernandez M.R. Laser Induced Ocular Hypertension in Mice. Mouse Genetics Group Annual Meeting April 2008. Chicago, Illinois, USA. Poster.
                                                                                                                                                                                                                                                                                                                45. Loewen N., Chen J., Dudley V.J., Sarthy V.J., Mathura J.R. Jr. Angiogenic Network in Hypoxic Müller Cells Involves the Very Low Density Lipoprotein Receptor. Association for Research in Vision in Ophthalmology 2007. Fort Lauderdale, Florida, USA. Poster.
                                                                                                                                                                                                                                                                                                                46. Loewen N., Mehta M.P., Dudley V.J., Mathura J.R. Jr. VLDLR and TRIB3 is Expressed in Rat Müller Cells and Upregulated in Hypoxia. Association for Research in Vision in Ophthalmology 2006. Fort Lauderdale, Florida, USA. Poster.
                                                                                                                                                                                                                                                                                                                47. Khare P.D., Loewen N., Barraza R., Fautsch M., Johnson D.H., Poeschla E.M. A Glaucoma Gene Therapy Model: Eighteen Cat Study Revealing Long-Term Targeted Genetic Modification of the Anterior Chamber by Lentiviral Vectors. American Society for Gene Therapy 2006, Baltimore, MD, USA. Talk.
                                                                                                                                                                                                                                                                                                                48. Khare P.D., Loewen N., Poeschla E.M. Suppression of Human Pancreatic Cancer Growth by Lentiviral Vector-Mediated Gene Transfer of Pigment Epithelium Derived Factor (PEDF). American Society for Gene Therapy 2006, Baltimore, MD, USA.
                                                                                                                                                                                                                                                                                                                49. Poeschla E.M., Loewen N., Rasmussen C., Teo W., Khare P., Kaufman P.L. Transduction of Nonhuman Primate Trabecular Meshwork With Lentiviral Vectors. Association for Research in Vision in Ophthalmology 2006. Fort Lauderdale, Florida, USA. Talk.
                                                                                                                                                                                                                                                                                                                50. Khare P, Teo W, Loewen N., Barraza R., Fautsch MP, Johnson D.H., Poeschla E.M. Long-Term Genetic Modification of Trabecular Meshwork by Lentiviral Vectors: An 18 Cat Study. Association for Research in Vision in Ophthalmology 2006. Fort Lauderdale, Florida, USA. Talk.
                                                                                                                                                                                                                                                                                                                51. Fautsch M.P., Bahler C.K., Vrabel A.M., Howell K.G., Loewen N., Poeschla E.M., Johnson D.H. Recombinant Myocilin Purified From Human Trabecular Meshwork Cells Increases Outflow Resistance in Human Anterior Segments but Only in the Presence of Aqueous Humor. Association for Research in Vision in Ophthalmology 2005. Fort Lauderdale, Florida, USA. Talk.
                                                                                                                                                                                                                                                                                                                52. Loewen N., Fautsch M.P., Teo W., Bahler C.K., Johnson D.H., Poeschla E.M. Long-Term. Genetic Modification of the Ocular Outflow Tract Coupled with Non-Invasive Real-Time Imaging of Gene Expression. American Society of Gene Therapy 2004, Minneapolis, Minnesota. Talk.
                                                                                                                                                                                                                                                                                                                53. Saenz D., Loewen N., Leske D., Good M., Howell K., Holmes J.M., Poeschla E.M. Cell Cycle-Dependent Transcription from Unintegrated Lentiviral Vector DNA Internal Promoters: Analyses with Class I Integrase Mutants. American Society of Gene Therapy 2004, Minneapolis, Minnesota. Talk.
                                                                                                                                                                                                                                                                                                                54. Saenz D., Loewen N., Leske D., Good M., Holmes J.M., Poeschla E.M. Class I lentiviral integrase mutants reveal cell-cycle dependent expression from persistent unintegrated proviral DNA: implications for HIV-1. International Workshop on HIV Persistence during Therapy 2004. Saint Martin, French West Indies. Talk.
                                                                                                                                                                                                                                                                                                                55. Poeschla E.M., Fautsch M.P., Loewen N., Teo W., Johnson D.H. Wild-type and mutant myocilin co-expression causes heterodimer formation and intracellular retention of wild-type protein without impairing proteasome function. Association for Research in Vision in Ophthalmology 2003. Fort Lauderdale, Florida, USA. Poster.
                                                                                                                                                                                                                                                                                                                56. Loewen N., Teo W., Fautsch M.P., Bahler C.K., Johnson D.H., Poeschla E.M. Dose-dependent, transgene specific in vivo toxicity in FIV transduced feline TM. Association for Research in Vision in Ophthalmology 2003. Fort Lauderdale, Florida, USA. Poster.
                                                                                                                                                                                                                                                                                                                57. Saenz D., Loewen N., Barraza R., Teo W., Whitwam T., Peretz M., Poeschla E. Markedly cell cycle-dependent expression phenotypes of class-I-integrase mutants of 2 lentiviruses (FIV, HIV): wild-type level expression from unintegrated lentiviral DNA. 10th Conference on Retroviruses and Opportunistic Infections 2002, Boston, USA. Poster.
                                                                                                                                                                                                                                                                                                                58. Loewen N., Bahler CK., Teo W., Whitwam T., Barraza R., Fautsch MF., Peretz M., Johnson DH., Poeschla EM. Second-Generation FIV vectors: Expression of eGFP in TM of Domestic Cats and Effects on Aqueous Outflow Facility in Human Anterior Segments. International Congress of Eye Research 2002, Geneva, Switzerland. Talk.
                                                                                                                                                                                                                                                                                                                59. Holmes JM., Loewen N., Leske DA., Teo W., Saenz T., Peretz M., Chen Y., Poeschla EM. Genomic integration and sustained transgene expression using an FIV-based lentiviral vector in retinal gene therapy. International Congress of Eye Research 2002, Geneva, Switzerland. Poster.
                                                                                                                                                                                                                                                                                                                60. Loewen N., Chen Y., Leske DA., Poeschla EM., Holmes JM. Increase of Neovascularization by Subretinal Injection in a Rat Model for Gene Therapy of Retinal Neovascularization (NV). American Society of Gene Therapy 2002, Boston, Massachusetts. Poster.
                                                                                                                                                                                                                                                                                                                61. Saenz D., Loewen N., Poeschla E. An auto-regulated, doxycycline-inducible FIV-based lentiviral vector. American Society of Gene Therapy 2002, Boston, Massachusetts. Poster.
                                                                                                                                                                                                                                                                                                                62. Loewen N., Leske DA., Chen Y., Saenz DT., Teo W., Fautsch MP., Holmes JM., Poeschla EM. Retinal gene expression after transduction with FIV and control FIV (class I integrase mutant) vectors: comparison to adenovirus vectors and validation of an important control for FIV vectors. American Society of Gene Therapy 2002, Boston, Massachusetts. Poster.
                                                                                                                                                                                                                                                                                                                63. Saenz D., Loewen N., Poeschla E. A class I FIV integrase mutant reveals short-term gene expression from unintegrated lentiviral vector DNA in non-dividing cells. American Society of Gene Therapy 2002, Boston, Massachusetts. Talk.
                                                                                                                                                                                                                                                                                                                64. Loewen N., Bahler CK., Teo W., Whitwam T., Barraza R., Fautsch MF., Peretz M., Johnson DH., Poeschla EM. Transduction of Human and Feline Eye Trabecular Meshwork with a Second Generation FIV Vector System: Effects on Aqueous Outflow and Monitoring of Expression in Live Animals. American Society of Gene Therapy 2002, Boston, Massachusetts. Poster.
                                                                                                                                                                                                                                                                                                                65. Holmes JM., Chen Y., Loewen N., Leske DA., Poeschla EM. Subretinal Injection Increases Neovascularization in Oxygen-Induced Retinopathy in the Neonatal Rat. Association for Research in Vision in Ophthalmology 2002. Fort Lauderdale, Florida, USA. Poster.
                                                                                                                                                                                                                                                                                                                66. Leske DA., Loewen N., Chen Y., Fautsch MP., Poeschla EM., Holmes JM.. Comparison of FIV and Adenovirus Mediated Long Term Transgene Expression in the Neonatal Rat Retina. Association for Research in Vision in Ophthalmology 2002. Fort Lauderdale, Florida, USA. Poster.
                                                                                                                                                                                                                                                                                                                67. Loewen N., Fautsch MP., Bahler CK., Johnson DH., Poeschla EM. Effects of FIV-Based Lentiviral Vector Transduction of Trabecular Meshwork on Aqueous Outflow Facility and In Vivo Monitoring of Expression in Cats. Association for Research in Vision in Ophthalmology 2002. Fort Lauderdale, Florida, USA. Talk.
                                                                                                                                                                                                                                                                                                                68. Loewen N., Saenz DT., Poeschla EM. A tetracycline inducible FIV-based lentiviral vector with full autoregulation of all components. Building Bridges Research Forum 2001, Mayo Foundation, Rochester, Minnesota. Poster.
                                                                                                                                                                                                                                                                                                                69. Whitwam T.A, Peretz M., Loewen N., Poeschla EM. Identification and Characterization of a Central DNA Flap in Feline Immunodeficiency Virus. Keystone Meeting 2001, Colorado. Poster.
                                                                                                                                                                                                                                                                                                                70. Whitwam T.A, Peretz M., Loewen N., Poeschla EM. Identification and Characterization of a Central DNA Flap in Feline Immunodeficiency Virus. American Society of Gene Therapy 2001, Seattle, Washington. Talk.
                                                                                                                                                                                                                                                                                                                71. Loewen N., Fautsch M., Xu R., Johnson DH., Poeschla EM. Transduction of Human Trabecular Meshwork with Lentiviral Vectors. American Society of Gene Therapy 2001, Seattle, Washington. Talk.
                                                                                                                                                                                                                                                                                                                72. Loewen N., Good M.S., Krebsbach V., Poeschla E.M., Johnson D.H. Transduction of retinal ganglion cells in culture using feline immunodeficiency virus. American Society of Gene Therapy 2001, Seattle, Washington. Talk.
                                                                                                                                                                                                                                                                                                                73. Loewen N., Leske D.A., Chen Y., Poeschla E.M., Holmes J.M. Gene transfer into neonatal rat retina using a lentiviral FIV vector. American Society of Gene Therapy 2001, Seattle, Washington. Poster.
                                                                                                                                                                                                                                                                                                                74. Leske D.A., Loewen N., Chen Y., Poeschla E.M., Holmes J.M. Gene transfer into neonatal rat retina using a lentiviral FIV vector. Association for Research in Vision in Ophthalmology 2001. Fort Lauderdale, Florida, USA. Talk.
                                                                                                                                                                                                                                                                                                                75. Good M.S., Krebsbach V., Loewen N., Poeschla E.M., Johnson D.H. Transduction of retinal ganglion cells in culture using feline immunodeficiency virus. American Glaucoma Association, California, USA, 2001. Talk.
                                                                                                                                                                                                                                                                                                                76. Loewen N., Fautsch M., Xu R., Johnson DH., Poeschla EM. Comparison of lentiviral, type C retroviral, and adenoviral vectors for transduction of human trabecular meshwork. Association for Research in Vision in Ophthalmology 2001. Fort Lauderdale, Florida, USA. Talk.
                                                                                                                                                                                                                                                                                                                77. Loewen N., Cameron JD., Fautsch M., Johnson DH., Poeschla EM. Highly Efficient Transduction of the Human Trabecular Meshwork with a New Minimal Lentiviral FIV Vector: Preclinical Investigations of Gene Therapy for Glaucoma and Rating of Different Vectors in a Human Eye Explant Model. From Molecule to Mankind 2000. Rochester, Minnesota, USA. Poster.
                                                                                                                                                                                                                                                                                                                78. Loewen N., Cameron JD., Fautsch M., Johnson DH., Poeschla EM. Minimal FIV Vector for the Transduction of the Trabecular Meshwork in a Human Eye Explant Model: Preclinical Investigations of Gene Therapy for Glaucoma. Stockholm, Sweden. 8th Meeting of the European Society of Gene Therapy, J Gene Med. 2000;2(5 Suppl):39. Poster.
                                                                                                                                                                                                                                                                                                                79. Loewen N., Fauser S. Ocular Gene Therapy with FIV. Bonn, Conference of the Federal Department of Research and Education, 1999. Poster.
                                                                                                                                                                                                                                                                                                                80. Loewen N., Dietrich TJ., Seelig B., Schiefer U. Fundus-oriented perimetry (FOP) for early detection of visual field defects in glaucoma. Berlin, Germany. 97th Conference of the German Society of Ophthalmology, 1999. Talk.
                                                                                                                                                                                                                                                                                                                81. Loewen N., Barry JC. The use of cycloplegic agents. Results Of a 1999 survey of German-speaking centers for pediatric ophthalmology and strabology. Cologne, Germany. 7th Conference of the Bielschowsky-Society, 1999. Talk.
                                                                                                                                                                                                                                                                                                                82. Loewen N., Weirich J. Heterogeneity of the electric activity within the ventricular wall: regionally different proarrhythmic effects of a potassium channel blockage of the fast component of the delayed rectifier. Vienna, Austria. 21st Conference of the Austrian Society of Cardiology, 1997. Poster.
                                                                                                                                                                                                                                                                                                                83. Loewen N., Weirich J. Electrophysiological properties of slices from the deep myocardium of the ventricular wall: regionally different effects of potassium channel blockage with the class-III antiarrhythmic MK499. Mannheim, Germany. 63rd Conference of the German Society of Cardiology, 1995. Talk.