Academic Affiliation

Nicolas A. Karakatsanis, PhD
Electrical and Computer Engineer
Research Scientist in Molecular Imaging

Cardiovascular Imaging Laboratory
Translational & Molecular Imaging Institute
Department of Radiology
Icahn School of Medicine at Mt Sinai Health System
New York, NY, USA

Previous Academic Affiliations

PET Instrumentation and Neuroimaging (PIN) Laboratory
Division of Nuclear Medicine at Geneva University Hospital
Faculty of Medicine, University of Geneva, Geneva, Switzerland


Tomographic Image Reconstruction and Analysis (TIRA) Lab

Division of Nuclear Medicine, Department of Radiology,

Johns Hopkins University, Baltimore, MD, USA

Primary Correspondence Address

Nicolas A. Karakatsanis, PhD
Cardiovascular Imaging Laboratory (Fayad lab)
Translational & Molecular Imaging Institute
Icahn School of Medicine at Mt Sinai Health System
1470 Madison Ave, TMII, 1st Floor
New York, NY, 10029, USA

Previous Correspondence Addresses

Nicolas A. Karakatsanis, PhD

c/o Habib Zaidi

PET Instrumentation and Neuroimaging Laboratory

Division of Nuclear Medicine, Geneva University Hospital

Site Cluse-Roseraie, Rue Gabrielle-Perret-Gentil 4

CH-1211, Geneva 14, Switzerland


Nicolas A. Karakatsanis, PhD

c/o Arman Rahmim, 
Division of Nuclear Medicine, 

Department of Radiology, 

Johns Hopkins Outpatient Center, Room 3263

Baltimore, MD, USA, 21287

Contact Details

Office Phone: +1 (410) 614 1738
Academic Web Site:
PINlab Web Site:
TIRAlab Web Site:

Dr. Nicolas A. Karakatsanis is Research Scientist at the Translational and Molecular Imaging Institute (TMII) at the Icahn School of Medicine at Mt Sinai Health System, located at New York, NY, USA. Since July 2015, he is a member of the Cardiovascular Imaging Lab led by the Director of the TMII, Prof. Zahi Fayad.

Nicolas is aiming to enhance the diagnostic, prognostic and theranostic value of pre-clinical and clinical Positron Emission Tomography (PET) images as well as the cancer treatment response monitoring capabilities of clinical PET systems, by developing clinically feasible and truly quantitative PET/CT and PET/MR imaging methodologies, using:
  • PET/CT as well as simultaneous PET/MR state-of-the-art clinical tomographic scanners and software
  • novel and clinically adoptable whole-body dynamic PET acquisition protocols
  • quantitative and multi-parametric simultaneous dynamic PET/MR cardiovascular imaging methods
  • efficient whole-body PET tracers kinetic modeling analysis coupled with robust kinetic parameter estimation techniques to enhance PET signal quantification at the voxel level
  • advanced 4D parametric PET/MR image reconstruction algorithms
  • innovative respiratory and cardiac non-rigid motion estimation and correction techniques within and after image reconstruction
  • synergistic PET/MR image reconstruction for efficient partial volume error (PVE) correction
  • utilization of Time-of-Flight (TOF), Continuous Bed Motion (CBM) Resolution Modeling (PSF) technologies for the benefit of static and dynamic whole-body and cardiovascular PET/CT and PET/MR imaging,
  • application of quantitative PET image reconstruction in oncology, cardiovascular and neuro PET/CT and PET/MR imaging and
  • NECR-based PET dosage optimization tailored for clinical PET/CT and PET/MR imaging applications
Previously, Dr Karakatsanis was appointed as a Postdoctoral Research Associate at Geneva University Hospital (Hôpitaux Universitaires de Genève, HUG) for the period between January 2014 and July 2015. There he had joined the PET Instrumentation and Neuroimaging laboratory (PINlab) led by Dr. Habib Zaidi, honorary professor also at the University Medical Center of Groningen (UMCG) in Netherlands.

He also maintains an active and close collaboration with the Tomographic Image Reconstruction and Analysis (TIRA) lab led by Dr Arman Rahmim, Assistant Professor of Radiology and Electrical and Computer Engineer at Johns Hopkins University. He had been appointed at Johns Hopkins University Hospital as a Postdoctoral Research Fellow from February 2011 to December 2013.

Furthermore, he is working closely with the Nuclear Imaging Medical lab (NIMlab) led by Dr George Loudos, Assistant Professor at the Biomedical Engineering Department of the Technical Educational Institute of Athens, Greece.