SCIENTIFIC PROGRAM




10th International Meeting
STEROIDS and NERVOUS SYSTEM



FEBRUARY 16   9-17 Satellite Symposium



FEBRUARY 16 - Meeting

14-17 Registration (Anatomy, Torino)


17.30 - Opening Ceremony



18.00   OPENING LECTURE

Ball G.F. (USA)

Pleiotropic effects of testosterone: lessons from studies of the avian song system

19.00 Welcome cocktail


FEBRUARY 17


SYMPOSIUM - Aromatase in the female brain - Why produce locally when available globally?


9.00 Cornil C.A. (Belgium): Neuroestrogens and female sexual behavior 

9.30 de Bournonville C., McGrath A., Mendoza K.R., Remage-Healey L. (USA) Steroid synthesis in the auditory forebrain of female zebra finches in response to song

10.00 Frick K.M. (USA): The role of hippocampal estradiol synthesis in regulating memory formation

10.30 Blaustein J.D. (USA): Aromatase inhibitors in postmenopausal women with breast cancer: what about the brain?

11.00-11.30 – Coffee break

11.30 Gintzler A.R., Storman E.M., Liu N.-J., Wessendorf M.W. (USA) Membrane estrogen receptor alpha and aromatase form signaling complexes in the CNS: implications for region-specific estrogenic signaling

11.45 Rehbein E., Hornung J., Morawetz C., Bayer J., Krylova M., Sundström Poromaa I., Derntl B. (Germany) Does estradiol influence behavioral and neural emotion regulation performance?


12.15-13.00 PLENARY LECTURE

Torres Aleman I. (Spain)

The blood-brain-barrier and the cross-talk of estradiol and IGF-1 in mood regulation


13.00-14.00 Lunch and Poster exhibition



SYMPOSIUM - Sex differences in fear and stress responses: relevance to disease vulnerability and treatment for psychopathology


14.00 Bangasser D. (USA): Sex differences in stress regulation and cognition

14.30 Dalla C., Kokras N. (Greece): Sex differences in psychopharmacology: from estrogens to neuroestrogens in models of depression

15.00 Milad M. (USA): Fear extinction: her and his brains

15.30 – 16.00 Coffee Break


SYMPOSIUM Prevention of behavioral disorders caused by stress-induced disruption of steroid pathways in pregnancy and in the early postnatal period.


16.00 Sze Y., Fernandes J., Gill A.C., Brunton P.(UK): Effects of prenatal stress on neurosteroid pathways in the offsprings

16.30 Matthews S. (Canada): Glucocorticoid Programming of the Fetal Brain: Intergenerational Consequences

17.00 Hirst J. (Australia): Loss of neurosteroid support contributes to adverse long term behavioural outcomes following preterm birth



17.30-18.30 Round table The problem with sex differences

Galea L. (Canada): Mandating the study of sex differences will NOT improve women’s health

Sohrabji F. (USA): Sex differences in therapeutics: is it time to consider a blue pill/pink pill?

Choleris E. (Canada): Underpowered research on sex differences and sex-specific analyses

McCarthy M.M. (USA) How the complexity of sex differences leads to misinterpretation and misunderstanding by researches and reviewers alike

 


FEBRUARY 18


SYMPOSIUM - Molecular mechanisms of glucocorticoid effects


9.00 De Franco D.B., Franks A.L., Berry K.J., Jaumotte J.D., Bargerstock Murillo E., Rudine A.R., Monaghan-Nichols A.P. (USA) Regulation of glucocorticoid responses in the developing rodent brain

9.30 Garabedian M.J., Chao M.V., Jeanneteau F. (USA): Regulation of glucocorticoid receptor phosphorylation and genomic action by brain-derived neurotrophic factor in cortical neurons

10.00 Krugers H. (The Netherlands): Glucocorticoid effects on memory formation: role of synapses and early life experiences

10.30 Hunter R. (USA): Glucocorticoid receptor interactions with the deep genome

 

 

11.00-11.30 – Coffee break


11.30- Crombie G.K., Palliser H.K., Shaw J.C., Hodgson D.M., Walker D.W., Hirst J.J. (Australia) Placental role in neuroprotective responses to prenatal stress in the guinea pig

11.45 Sivukhina E.V., Jirikowski G.F. (Germany) Corticosteroid-binding globulin expression is upregulated upon increased magnocellular neuronal activity in rats




12.15-13.00 PLENARY LECTURE

Pariante C. (UK)

Glucocorticoids, inflammation and psychiatric illness



13.00-14.00 Lunch and Poster exhibition

 


SYMPOSIUM Countering neuroactive steroids: a novel therapeutic avenue in neuropsychiatry?


14.00 Di Paolo T., Litim N., Poirier A-A., Jarras H., Côté M., Al Sweidi S., Morissette M., Caruso D., Melcangi R., Soulet D. (Canada) Effects of 5alpha-reductase inhibitors in the brain and gut of MPTP mouse model of Parkinson’s disease

 

14.30 Frau R., Traccis F., Fanni S., Giua G., Saba P., Caruso D., Scheggi S., Soggiu A., Roncada P., Devoto P., Bortolato M. (Italy) Blocking neurosteroidogenesis as a novel tool for the cognitive complications of sleep disorders

 

15.00 Bortolato M. (USA) Inhibition of neurosteroidogenesis as a therapy for impulse-control problems and substance use disorders

15.30-16.00 Coffee break


SYMPOSIUM Toward a sex dimorphic neurology


16.00 Rocca W.A. (USA): Sex, gender and Parkinson’s disease

16.20 Mielke M.M. (USA): Sex, gender and dementia

16.40 Vemuri P. (USA): Sex differences in imaging biomarkers in aging and cognitive resilience

17.00 Miller V.M., Jayachandran M., Barnes J.N., Mielke M.M., Kantarci K., Rocca W.A. (USA) Sex, hormones and neurovascular aging



FEBRUARY 19

SYMPOSIUM - Sex differences and effects of neuroactive steroids on brain mitochondrial function and metabolism


8.30 Acaz-Fonseca E., Ortiz-Rodriguez A., Lopez-Rodriguez A.B., Garcia-Segura L.M., Heyde I., Oster H., Astiz M. (Germany) Developmental effects of neuroactive steroids in mouse brain mitochondria

 

9.00 Frago L.M., Guerra-Cantera S., Freire-Regatillo A., Barrios V., Argente J., Chowen J.A. (Spain) Sex differences in the neuroendocrine control of metabolism and the implication of astrocytes

 

9.30 Barreto  G.E. (Colombia) Tibolone reduces oxidative damage and inflammation in microglia stimulated with palmitic acid through mechanisms involving estrogen receptor beta

 

10.00-10.30 Coffee break

10.30 Eckert A. (Switzerland) Effects of sex hormones on mitochondrial activity and bioenergetics – implications for Alzheimer’s disease

 

11.00 Kammel L.G., Van Veen J.E., Bunda P.C., Shum M., Zhang Z., Massa M.G., Reid M.S., Hrncir H., Arnold A.P., Liesa M., Yang X., Correa S.M. (USA) Sex differences in the transcriptional architecture of the VMH reveal two estrogen-sensitive neuron clusters that coordinately regulate energy expenditure in females

 

11.15 Raval P., Mukherjee J., Sellers K.J., Creeney H., Durate R.R.R., Moss S.J., Brandon N.J., Srivastava D.P. (UK) Estradiol regulates the synaptic proteome through a local translation mechanism in a sexually dimorphic manner.



11.30-12.15 SPECIAL LECTURE

Shah N.M. (USA)

Molecular and neural control of sexually dimorphic social behaviors



 

12.15-14.00 Lunch and POSTER DISCUSSION



SYMPOSIUM Multi-faceted functions of estrogens in the ventromedial hypothalamic nucleus


14.00 Xu Y. (USA): An estrogen-responsive neural network: start from the ventromedial hypothalamic nucleus

14.30 López M. (Spain): Complex lipid metabolism within the VMH mediates the central actions of estradiol on energy balance

15.00 Routh V. (USA): Estrogen regulation of ventromedial hypothalamus glucose-inhibited neurons may play a role in glucose homeostasis

15.30 Lin D. (USA) The VMHvl and female aggression

16-19 Organized tours of City Museums

https://www.museireali.beniculturali.it/en/plan-your-visit/

see also this page


20.30 SOCIAL DINNER

(Restaurant Il Bric, Colle della Maddalena, Torino)

Restaurant Il bric

A view of Torino from the Colle della Maddalena
Colle della Maddalena




FEBRUARY 20


SYMPOSIUM - Molecular tools unleashed for the study of neuroactive steroid synthesis and action


9.00 Remage-Healey L. (USA): Viral targeting of neuronal subtypes to dissect rapid neurosteroid regulation of sensory cortex

9.30 Moenter S. (USA): Estradiol feedback on the reproductive neuroendocrine system

10.00 Ábrahám I.M., Barabás K., Kovács T., Kovács G., Ernszt D., Jánosi T.Z., Godó S. (Hungary) Super-resolution imaging of rapid estradiol effects on surface movement of glutamate receptors in live neurons

10.30 Stincic T. (USA): Optogenetics and calcium imaging reveal novel actions of estrogenic signaling on hypothalamic circuits that regulate energy balance

 


11.00 Routh V. (USA): Estrogen regulation of ventromedial hypothalamus glucose-inhibited neurons may play a role in glucose homeostasis

11.30 Lin D. (USA) The VMHvl and female aggression


12.00-13.00 PLENARY LECTURE

Prevot V. (France)

Hypothalamic neuronal circuits controlling reproduction and steroid hormones: a role for nitric oxide?


13.00-13.45 Lunch


13.45 Winners of Young Investigators' Prizes



14.00-15.00 YOUNG INVESTIGATORS Symposium

14.00 Marrocco J., Einhorn N.R., Li H., Schmidt P.J., Lee F.S., McEwen B.S. (USA) Cross-species epigenetic signature induced by ovarian hormones.

14.10 De Wit A.E., Booij S.H., Giltay E.J., Joffe H., Schoevers R.A., Oldehinkel A.J. (the Netherlands) Associations of oral contraceptive use and depressive symptoms in adolescents and young women

14.20 Duarte-Guterman P., Lieblich S.E., Mahmoud R., Ibrahim M., Skandalis D.A., Galea L.A.M. (Canada) The short and long term impact of motherhood on hippocampal neurogenesis, inflammation, and gene expression

14.30 Mariani N., Cattaneo A., Calpighi C., McLaughlin A.P., Nikkheslat N., Hastings C., Nettis M.A., Zajowska Z., Cowen P., Cavanagh J., Harrison N., Bullmore E., The Wellcome Trust NeuroImmunology of Mood disorders and Alzheimer’s disease (NIMA) consortium, Mondelli V., Pariante C.M. (UK) Modulation of glucocorticoid receptors in the blood mRNA of patients with depression: a study in treatment resistant, treatment responsive, or untreated patients

14.40 Turano, A., Haas, N.A. M.S., Schwarz, J.M. PhD (USA) Examining the impact of neuroimmune dysregulation on social behavior in male and female juvenile rats

14.50 Viho E.M.G., Buurstede J.C., Koorneef L.L., Mahfouz A., Houtman R., Hunt H., Kroon J., Meijer O.C. (the Netherlands) Putative coregulator interactions underlying differential glucocorticoid receptor modulation effects in memory consolidation


SYMPOSIUM - Vitamin D and brain


15.00 Norlin M. (Sweeden): Vitamin D and the brain  - potential effects on steroidogenesis in the nervous system and possible role in the treatment of brain cancer

15.30 Jirikowski G.F. (Germany): Vitamin D binding proteins and their localization in the nervous system

16.00 Cui X. (Australia): Vitamin D modulates dopamine development via its genetic and epigenetic actions

16.30-17.00 Coffee break


SYMPOSIUM - The impact of endocrine disrupting chemicals (EDCs) interfering with steroid signaling on neurodevelopment


17.00 Patisaul H. (USA) The CLARITY-BPA Project: Reproductive evidence of low dose effects on the developing brain

17.30 Lichtensteiger W., Bassetti-Gaille C., Rehrauer H., Kühn Georgijevic J., Tresguerres J.A.F., Schlumpf M. (Switzerland) Sex-dependent effects of behaviorally active chemicals on genes regulating interneuron development in hippocampus: possible role of microRNA

18.00 Parent A.S., López-Rodríguez D., Franssen D., Lomniczi, A., Bourguignon J.P. (Belgium) Neuroendocrine disruption of puberty and reproduction

 

CLOSURE OF THE MEETING


Subpages (1): Visit to Royal Museums
Ċ
Giancarlo Panzica,
Feb 13, 2019, 1:58 AM
Ċ
Giancarlo Panzica,
Feb 13, 2019, 1:58 AM