MutExSL

NEW BOOK!! (2017) Computational prediction of protein complexes from protein interaction networks, published by ACM Books and Morgan & Claypool.


Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer


Sriganesh Srihari1, Jitin Singla2, Limsoon Wongand Mark A. Ragan1

1 Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4067, Australia

2 Department of Computer Science and Engineering, Indian Institute of Technology Roorkee, Uttarakhand 247667, India

3 Department of Computer Science, National University of Singapore, Singapore 117417, Singapore


Contact: sriganesh [dot] m [dot] s [at] gmail [dot] com


Citation: Srihari S, Singla J, Wong L, Ragan MA (2015) Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer. Biology Direct 10:57 [PDF] [Article in Biotechin.asia]

S Srihari, J Singla, L Wong, PT Simpson, KK Khanna and MA Ragan (2016) Abstract PD6-05: Identifying genetic vulnerabilities in cancers driven by defects in DNA-damage response. Cancer Research 0.1158/1538-7445.SABCS15-PD6-05. [PDF] (Presented at the San Antonio Breast Cancer Symposium, San Antonio, Texas (USA), Dec 2015) -- AACR-Susan G. Komen award.




Supplementary materials

Download here [Excel] -- list of SL partners of six DDR genes
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