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Publications and patents



     1) Exogenous chondroitin sulfate glycosaminoglycan associate with arginine-rich peptide-DNA complexes to alter their intracellular processing and gene delivery efficiency
          Naik RJ, Sharma R, Nisakar D, Purohit G, Ganguli M.
          Biochim Biophys Acta. 2015 Apr;1848(4):1053-64.
          PubMed ID: 25637297 


     1) Contrasting effects of cysteine modification on the transfection efficiency of amphipathic peptides.
         Sharma R, Nisakar D, Shivpuri S, Ganguli M.
         Biomaterials. 2014 Aug;35(24):6563-75.

         PubMed ID: 24816284

     2) Linear Short Histidine and Cysteine Modified Arginine Peptides Constitute a Potential Class of DNA Delivery Agents.
         Mann A, Shukla V, Khanduri R, Dabral S, Singh H, Ganguli M.
         Mol Pharm. 2014 Jan 29. [Epub ahead of print]

         PubMed ID: 24476132


    1)  Integration host factor of Mycobacterium tuberculosis, mIHF, compacts DNA by a bending mechanism.
         Mishra A, Vij M, Kumar D, Taneja V, Mondal AK, Bothra A, Rao V, Ganguli M, Taneja B.
         PLoS One. 2013 Jul 26;8(7):e69985.

         PubMed ID: 23922883

    2)  Insight into the role of physico-chemical parameters in a novel series of amphipathic peptides for efficient DNA delivery
         Sharma R,  Shivpuri S,  Anand A, Kulshreshtha A,  Ganguli M
Mol Pharm. 2013 Jul 1;10(7):2588-600. doi: 10.1021/mp400032q. Epub 2013 Jun 3.
PubMed ID: 
    3)  Different roles of cell surface and exogenous glycosaminoglycans in controlling gene delivery by arginine-rich peptides with varied distribution of arginines.

         Naik RJ, Chatterjee A, Ganguli M.

         Biochim Biophys Acta. 2013 Jun;1828(6):1484-93.

         PubMed ID: 23454086

    4) Synthesis, characterization of penicillin G capped silver nanoconjugates to combat β-lactamase resistance in infectious microorganism.

        Ahmed V, Kumar J, Kumar M, Chauhan MB, Vij M, Ganguli M, Chauhan NS.

        J Biotechnol. 2013 Feb 20;163(4):419-24

        PubMed ID: 23305990


1) Highly efficient (R-X-R)-type carbamates as molecular transporters for cellular delivery.

    Patil KM, Naik RJ, Rajpal, Fernandes M, Ganguli M, Kumar VA.

    J Am Chem Soc. 2012 May 2;134(17):7196-9.

   PubMed ID:  22509923


2) Structural rearrangements and chemical modifications in known cell penetrating peptide strongly enhance DNA delivery efficiency.

    Rajpal, Mann A, Khanduri R, Naik RJ, Ganguli M.

    J Control Release. 2012 Jan 30;157(2):260-71. 

    PubMed ID: 21996011


1) Differences in DNA condensation and release by lysine and arginine homopeptides govern their DNA delivery efficiencies.

    Mann A, Thakur G, Shukla V, Singh AK, Khanduri R, Naik R, Jiang Y, Kalra N, Dwarakanath BS, Langel U, Ganguli M.

    Mol Pharm. 2011 Oct 3;8(5):1729-41. 

    PubMed ID21780847

 2) Exogenous and cell surface glycosaminoglycans alter DNA delivery efficiency of arginine and lysine homopeptides in distinctly different ways.

    Naik RJ, Chandra P, Mann A, Ganguli M.

    J Biol Chem. 2011 May 27;286(21):18982-93. 

    PubMed ID: 21471199


1) Leishmania actin binds and nicks kDNA as well as inhibits decatenation activity of type II topoisomerase.

    Kapoor P, Kumar A, Naik R, Ganguli M, Siddiqi MI, Sahasrabuddhe AA, Gupta CM.

    Nucleic Acids Res. 2010 Jun;38(10):3308-17. 

    PubMed ID20147461


1) Nanoparticles of cationic chimeric peptide and sodium polyacrylate exhibit striking antinociception activity at lower dose.

   Gupta K, Singh VP, Kurupati RK, Mann A, Ganguli M, Gupta YK, Singh Y, Saleem K, Pasha S, Maiti S.

   J Control Release. 2009 Feb 20;134(1):47-54. 

   PubMed ID: 19014986

2) Gene delivery to the retina: focus on non-viral approaches.

    Naik R, Mukhopadhyay A, Ganguli M.

    Drug Discov Today. 2009 Mar;14(5-6):306-15.

    PubMed ID: 18973824


1) DNA organization by the apicoplast-targeted bacterial histone-like protein of Plasmodium falciparum.

   Ram EV, Naik R, Ganguli M, Habib S.

   Nucleic Acids Res. 2008 Sep;36(15):5061-73.

   PubMed ID: 18663012


2) Peptides in DNA delivery: current insights and future directions.

    Mann A, Thakur G, Shukla V, Ganguli M.

    Drug Discov Today. 2008 Feb;13(3-4):152-60. 

    PubMed ID: 18275913

3) DNA condensation by poly-L-lysine at the single molecule level: role of DNA concentration and polymer length.

   Mann A, Richa R, Ganguli M.

   J Control Release. 2008 Feb 11;125(3):252-62. 

    PubMed ID: 18068848

4) Properties of Bacillus anthracis spores prepared under various environmental conditions.

    Baweja RB, Zaman MS, Mattoo AR, Sharma K, Tripathi V, Aggarwal A, Dubey GP, Kurupati RK, Ganguli M, Chaudhury NK, Sen S, Das TK, Gade WN, Singh Y.

    Arch Microbiol. 2008 Jan;189(1):71-9.

    PubMed ID: 17713759


1) Inhibition of protein aggregation: supramolecular assemblies of arginine hold the key.

   Das U, Hariprasad G, Ethayathulla AS, Manral P, Das TK, Pasha S, Mann A, Ganguli M, Verma AK, Bhat R, Chandrayan SK, Ahmed S, Sharma S, Kaur P, Singh TP, Srinivasan A.

   PLoS One. 2007 Nov 14;2(11):e1176.

   PubMed ID: 18000547

2) Interface peptide of Alzheimer's amyloid beta: application in purification.

    Das U, Hariprasad G, Pasha S, Mann A, Ganguli M, Sharma S, Kaur P, Singh TP, Srinivasan A.

    Biochem Biophys Res Commun. 2007 Oct 19;362(2):538-42. 

    PubMed ID: 1770778


3) Atomic force microscopy reveals the assembly of potential DNA "nanocarriers" by poly-L-ornithine.

    Mann A, Khan MA, Shukla V, Ganguli M.

    Biophys Chem. 2007 Sep;129(2-3):126-36.

    PubMed ID: 17601648


1)  PEI-alginate nanocomposites as efficient in vitro gene transfection agents.

     Patnaik S, Aggarwal A, Nimesh S, Goel A, Ganguli M, Saini N, Singh Y, Gupta KC.

     J Control Release. 2006 Sep 12;114(3):398-409. 

     PubMed ID: 16891026

2) Blood compatibility of novel water soluble hyperbranched polyglycerol-based multivalent cationic polymers and their interaction with DNA.

    Kainthan RK, Gnanamani M, Ganguli M, Ghosh T, Brooks DE, Maiti S, Kizhakkedathu JN.

    Biomaterials. 2006 Nov;27(31):5377-90. 

    PubMed ID: 16854460

3) Water soluble nanoparticles from PEG-based cationic hyperbranched polymer and RNA that protect RNA from enzymatic degradation.

    Khan JA, Kainthan RK, Ganguli M, Kizhakkedathu JN, Singh Y, Maiti S.

    Biomacromolecules. 2006 May;7(5):1386-8.

    PubMed ID: 16677017

4) Nanoparticle formation from poly(acrylic acid) and oppositely charged peptides.

   Gupta K, Ganguli M, Pasha S, Maiti S.

   Biophys Chem. 2006 Feb 1;119(3):303-6. 

   PubMed ID : 16243428

Before 2006

1) Imaging and analysis of Bacillus anthracis spore germination.

   Zaman MS, Goyal A, Dubey GP, Gupta PK, Chandra H, Das TK, Ganguli M, Singh Y.

   Microsc Res Tech. 2005 Apr 15;66(6):307-11.

   PubMed ID : 16003786

2) Complex formation between cationically modified gold nanoparticles and DNA: an atomic force microscopic study.

   Ganguli M, Babu JV, Maiti S.

   Langmuir. 2004 Jun 22;20(13):5165-70.

   PubMed ID : 15986644

3) Complexes of poly(ethylene glycol)-based cationic random copolymer and calf thymus DNA: a complete biophysical characterization.

    Nisha CK, Manorama SV, Ganguli M, Maiti S, Kizhakkedathu JN.

    Langmuir. 2004 Mar 16;20(6):2386-96.

    PubMed ID : 15835700

4) Nanoparticles from cationic copolymer and DNA that are soluble and stable in common organic solvents.

   Ganguli M, Jayachandran KN, Maiti S.

   J Am Chem Soc. 2004 Jan 14;126(1):26-7

   PubMed ID : 14709042


1) Novel Amphipathic Mgpe Peptides for Efficient Transfection of Biomolecules

    Munia Ganguli, Rajpal, Shivangi Shivpuri.0162nf2012, 3436del2012

2) Novel Peptide Carrier For Nucleic Acid Delivery
 Munia Ganguli, Anita Mann, Vasundhara Shukla, Manika Vij. 0163nf2012, 3435del2012