Welcome to the Mizutani lab!
We are interested in understanding the developmental mechanisms of evolutionary change in body plan patterns. We use the fruit fly Drosophila melanogaster and its closely related species to study how embryonic germ layers and morphogenetic gradients were modified during evolution. This research is currently funded by the National Science Foundation.
We are also performing genome-wide screenings to identify genes involved in other aspects of phenotypic differentiation in the sibling species D. melanogaster, D. simulans and D. sechellia, in particular: myogenesis, neuromuscular junction formation, locomotion, and germline specification.
Another project in our lab uses high resolution imaging of gene expression patterns and clonal analysis tools to visualize changes in the aging adult brain with single cell resolution. This research is currently funded by the National Institutes of Health, under the NIH Common Fund Single Cell Analysis Program. This project is done in collaboration with Dr. Rui Sousa-Neves (Visit Sousa-Neves lab).
See our Research projects link for more information.
Our new students joining the lab in August 2016:
Luke Stevens is our new PhD student.
Robert Allen joins our lab as a MS student .
Aravindan is our new undergraduate student.
Our list of Spring 2016 graduations:
Natalie Worden is attending Vet School at Cornell University.
Erik Hlosek is now a graduate student at CWRU Medical School.
Juliana Ross moved back to New York City and is pursuing graduate school at Columbia University.
Congratulations and best wishes in your future endeavors!
Natalie Worden received 3rd place in the Michelson-Morley research award in May 2016. Her work investigated the evolution of larval locomotion in related fly species.
Shelby Snashall graduated in May 2015 and is now attending PA School at Ohio State University. Shelby did independent research at our lab on two projects and received the Summer P-SURG research award in 2014. She also hired, trained and supervised a number of work-study students at our lab.
Hyun Lee graduated in May 2015, after spending all his undergraduate years doing research with us. He received four awards: Summer P-SURG fellowship, Russel M. Lawall Prize for Excellence in Biology, Case Alumni Scholarship and the John Schoff Millis Award. He is now attending Medical School in St. Louis.
Joe Schinaman successfully defended his PhD thesis in the summer of 2015 and moved to UCLA to do a postdoc at the Walker lab on fly aging.
Sebastian successfully defended his PhD thesis in July 2015 and is now doing a postdoc at the John Carlson lab at Yale University.
Luke Stevens joins the lab as research assistant in December 2014.
Our dati paper in collaboration with Sousa-Neves group is selected to feature on PLoS Biology journal cover of October/2014 issue.
Dr. Mizutani and Dr. Sousa-Neves receive a new NIH grant to study gene regulation during adult brain aging.
Joe's paper is published in PLoS Biology! Congratulations! To find out more about "datilografo" gene and how female flies say yes to males, see the paper and press release in Science Today, PLoS Biologue and SciGuru.
Priscilla's paper on Dorsal gradient modeling in Drosophila species is published in PLoS Computational Biology! See paper here
Our new PhD student Youngqiang Xue is joining the lab this Fall/2014.