Welcome to the Mizutani lab!
We are interested in understanding the developmental mechanisms of evolutionary change in body plan patterns. We use the fruit fly Drosophila melanogaster and its closely related species to study how embryonic germ layers and morphogenetic gradients were modified during evolution. This research is currently funded by the National Science Foundation.
We are also performing genome-wide screenings to identify genes involved in other aspects of phenotypic differentiation in the sibling species D. melanogaster, D. simulans and D. sechellia, in particular: myogenesis, neuromuscular junction formation, locomotion, and germline specification.
Another project in our lab uses high resolution imaging of gene expression patterns and clonal analysis tools to visualize the neural stem cell transcriptome with single cell resolution. This research is currently funded by the National Institutes of Health, under the NIH Common Fund Single Cell Analysis Program. This project is done in collaboration with Dr. Rui Sousa-Neves and Dr. Weihong Guo.
See our Research projects link for more information.
Luke Stevens joins the lab as research assistant in December 2014.
Our dati paper is selected to feature on PLoS Biology journal cover of October/2014 issue.
Dr. Mizutani and Dr. Sousa-Neves receive a new NIH grant to study gene regulation during adult brain aging.
Joe's paper is published in PLoS Biology! Congratulations! To find out more about "datilografo" gene and how female flies say yes to males, see the paper and press release in Science Today, PLoS Biologue and SciGuru.
Priscilla's paper on Dorsal gradient modeling in Drosophila species is published in PLoS Computational Biology! See paper here
Our new PhD student Youngqiang Xue is joining the lab this Fall/2014.