CONTACT
+34 935813785miriam.perez@uab.cat
Servei de Ressonància Magnètica NuclearEdifici C - Campus UAB08193 - Cerdanyola del VallèsBarcelona, Spain
Dr Míriam Pérez-Trujillo
PhD in Chemistry in the Universitat Autònoma de Barcelona (UAB) (2000-2004). Thesis subject: Synthesis and study of new Chiral Solvating Agents for the differentiation of enantiomers by NMR spectroscopy. Graduate in Chemistry at the UAB (1995-1999)
ORCID / SCOPUS / RESEARCH ID
RESEARCH ACTIVITY
Permanent researcher at the NMR research group of Dr. Teodor Parella at the Servei de RMN of the UAB, SeRMN-UAB (2005 to present)
Visiting researcher at the group of Dr. L. T. Kuhn, European Neuroscience Institute & Max Planck Institute for Biophysical Chemistry, Göttingen (2012)
Visiting researcher at the group of Prof. J. K. Nicholson and Prof. J. C. Lindon, Imperial College London (2010 and 2011)
Visiting PhD student at the group of Prof. A. P. Davis, University of Bristol (2002)
RESEARCH INTERESTS
Chiral recognition; In situ study of small organic molecules (metabolites and others) in complex (bio)mixtures using NMR spectroscopy; Development of enantiospecific methods for the in situ analysis of chiral organic molecules (e.g. drug degradation compounds, endogenous metabolites...) in complex mixtures; Metabolomics and metabolic profiling (Methods and Applications); Chiral metabolomics; Development of advanced NMR methods
LECTURER ACTIVITY
Adjunct lecturer at the Department of Chemistry, UAB (2012 to present)
SELECTED PUBLICATIONS
· Hyperpolarization-Enhanced NMR Spectroscopy of Unaltered Biofluids Using Photo-CIDNP , Kuhn, L. T.,* Weber, S., Bargon, J., Parella, T., Pérez-Trujillo, M.* Anal.Chem., 2023. DOI
· Simultaneous Enantiospecific Detection of Multiple Compounds in Mixtures using NMR Spectroscopy, Kuhn, L. T., Motiram-Corral, K., Athersuch, T. J., Parella, T. and Pérez-Trujillo, M.* Angew. Chem. Int. Ed., 2020, 59, 23615-23619. DOI
· Direct monitoring of exogenous GHB in body fluids by NMR spectroscopy, M. Palomino-Schätzlein, Y. Wang, A. D. Brailsford, T. Parella, D. A. Cowan, C. Legido-Quigley and M. Pérez-Trujillo* Analytical Chemistry, 2017, 89, 8343–8350. DOI
· Molecule confirmation and structure characterization of pentatriacontatrienyl mycolate in Mycobacterium smegmatis, M. Llorens-Fons, E. Julián, M. Luquin and M. Pérez-Trujillo* Chemistry and physics of lipids, , 2018, 212, 138-143 . DOI
· Chiral recognition by dissolution DNP NMR spectroscopy of 13C-labeled DL-methionine, E. Monteagudo, A. Virgili, T. Parella, M. Pérez-Trujillo* Analytical Chemistry, 2017, 89, 4939-4944. DOI
· NMR-aided differentiation of enantiomers: Signal enantioresolution, M. Pérez-Trujillo, T. Parella and L. T. Kuhn* Analytica Chimica Acta, 2015, 876, 63-70. DOI
· Simultaneous 1H and 13C NMR enantiodifferentiation from highly resolved pure shift HSQC spectra, M. Pérez-Trujillo, L. Castañar, E. Monteagudo, P. Nolis, L.T. Kuhn, A. Virgili, R. Thomas Williamson and T. Parella* Chemical Communications, 2014, 50, 10214-10217. DOI
· 13C NMR spectroscopy for the differentiation of enantiomers using chiral solvating agents, M. Pérez-Trujillo*, E. Monteagudo, T. Parella Analytical Chemistry, 2013, 85, 10887–10894. DOI
· Strong relationship between elemental stoichiometry and metabolome in plants, A. Rivas-Ubach*, J. Sardans, M. Pérez-Trujillo, M. Estiarte, J. Peñuelas Proc Natl Acad Sci USA, 2012,109, 4181-4186. DOI
· Ecometabolomics: optimized NMR-based protocol, A. Rivas-Ubach*, M. Pérez-Trujillo*, J. Sardans, A. Gargallo-Garriga, T. Parella, J. Peñuelas Methods in Ecology and Evolution, 2013, 4, 464-473. DOI
· Chiral Metabonomics: 1H NMR-based enantiospecific differentiation of metabolites in human urine via direct cosolvation with b-cyclodextrin, M. Pérez-Trujillo, J. C. Lindon, T. Parella, H. C. Keun, J. K. Nicholson, T. J. Athersuch* Analytical Chemistry, 2012, 84, 2868-2874. DOI
· Metabolic profiling detects early effects of environmental and lifestyle exposure to cadmium in a human population, J. K. Ellis, T. J. Athersuch, L. DK. Thomas, F. Teichert, M. Pérez-Trujillo, C. Svendsen, D. J. Spurgeon, R. Singh, L. Järup, J. G. Bundy, H. C. Keun* BMC Medicine, 2012, 10:61. DOI
· Efficient and rapid determination of the enantiomeric excess of drugs with chiral solvating agents: carvedilol, fluoxetine and a precursor of diarylether lactams, M. Pérez-Trujillo,* A. Virgili Tetrahedron: Asymmetry, 2006, 17, 2842-2846. DOI