THC / Cannabis as cancer
Study Indicates THC May Eradicate Brain Tumors
Seth Group: Nontoxic Dose of Delta9-THC Kills Human Brain Tumor
Antineoplastic activity of cannabinoids
Cannabinoids in pancreatic cancer: Correlation with survival and
Dr. Robert J. Melamede Ph.D. Chairman of the Biology Department of
the University of Colorado: Conducting Scientific research on
Cannabinoids protect against sunburn and skin cancer because of
the CB1 receptors in our skin.
Unlocking a Cure for Cancer – With Pot
THC to cure skin cancer?
Well, not just skin cancer. It has
been documented, even videotaped (www.sethgroup.org)
that THC from the cannabis plant attacks cancerous and mutated cells
while leaving healthy cells unharmed
One fascinating aspect of Dr. Manuel Guzman’s work is that, as
the tumors being treated are in brain (nerve) tissue, the
neuroprotective properties of THC become extremely important. Whereas
most cancer treatments cause damage to surrounding tissue (especially
crucial in the brain), THC treatments actually protect adjacent
non-cancerous nerve tissue.
Anti-Cancer Properties of THC - Research in Print:
Parolaro and Massi. 2008. Cannabinoids as a potential new drug
therapy for the treatment of gliomas. Expert Reviews of
Neurotherapeutics 8: 37-49
 Guzman et al. 2006. A pilot
clinical study of delta-9-tetrahydrocannabinol in patients with
recurrent glioblastoma multiforme. British Journal of Cancer.
Galanti et al. 2007. Delta9-Tetrahydrocannabinol inhibits cell cycle
progression in human glioblastoma multiforme cells. Acta Oncologica
 Calatozzolo et al. 2007. Expression of cannabinoid
receptors and neurotrophins in human gliomas. Neurological Sciences
 Cannabinoids selectively inhibit proliferation
and induce death of cultured human glioblastoma multiforme cells.
Journal of Neurooncology. 2005
 Cannabinoids and cancer. Mini-Reviews in Medicinal Chemistry.
 The endogenous cannabinoid, anandamide, induces cell death in
colorectal carcinoma cells. Gut. 2005
 Cannabinoid receptor as a novel target for the treatment of
prostate cancer. Cancer Research. 2005
 Antitumor effects of cannabidiol, a nonpsychoactive
cannabinoid, on human glioma cell lines. Journal of Pharmacology And
Experimental Therapeutics. 2004
 Cannabinoids inhibit the vascular endothelial growth factor
pathway in gliomas. Cancer Research. 2004
 Delta-9 tetrahydrocannabinol (THC) inhibits lytic
replication of gamma oncogenic herpesviruses in vitro. BMJ Medicine.
 Cannabinoids: potential anticancer agents. Nature Reviews
 Inhibition of tumor angiogenesis by cannabinoids. The FASEB
 Inhibition of skin tumor growth and angiogenesis in vivo by
activation of cannabinoid receptors. Journal of Clinical
 Anti-tumoral action of cannabinoids: involvement of
sustained ceramide accumulation and extracellular signal-regulated
kinase activation. Nature Medicine. 2000
 Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma
cells. FEBS Letters. 1998
 The endogenous cannabinoid anandamide inhibits human breast
cancer cell proliferation. Proceedings of the National Academy of
Sciences of the USA. 1998
 Toxicology and Carcinogenesis
Studies of 1 trans-delta-9-tetrahydrocannabinol in F344N/N Rats and
BC63F1 Mice. National Institutes of Health National Toxicology
Program, NIH Publication No. 97-3362. 1996.
activity of cannabinoids. Journal of the National Cancer Institute.
Recent Research on Medical Marijuana
Delta9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T
Cells Is Regulated by Translocation of Bad to Mitochondria
Anti-tumoral action of cannabinoids: Involvement of sustained
ceramide accumulation and extracellular signal-regulated kinase
See also ASA Forum Cannabis and Cancer