Distribution and survival of Borrelia miyamotoi in human blood components
Aaron M. Thorpe and Laura TonnettiArticle first published online: 21 DEC 2015
*Address reprint requests to: Laura Tonnetti, PhD, Scientific Affairs, American Red Cross Holland Laboratory, 15601 Crabbs Branch Way, Rockville, MD 20855; e-mail: Laura.Tonnetti@redcross.org.
Borrelia miyamotoi, the agent of relapsing fever, is a tick-borne spirochete first isolated in Japan in 1994. Since then, the spirochete has been detected in ticks globally, generally in the same vectors as the Lyme disease agent. Human infection has been reported in Russia, Europe, Japan, and the United States, as influenza-like febrile illness. In addition, two cases of meningoencephalitis caused by B. miyamotoi have also been reported in immunocompromised patients. Here we evaluate the ability of the spirochete to survive in human blood components stored under standard blood bank conditions.