Mesci P, Macia A, LaRock CN, Tejwani L, Fernandes IR, Suarez NA, Zanotto PM, Beltrão-Braga PC, Nizet V, Muotri AR. Modeling neuro-immune interactions during Zika virus infection. Human Molecular Genetics


Valderrama J, Riestra A, Gao N, LaRock C, Ali S, Gupta N, Hoffman H, Ghosh P, Nizet V. Group A streptococcal M protein activates the NLRP3 inflammasome. Nature Microbiology

Döhrmann S, LaRock C, Anderson E, Cole J, Ryali B, Stewart C, Nonejuie P, Pogliano J, Corriden R, Ghosh P, Nizet V. Group A streptococcal M1 protein provides resistance against the antimicrobial activity of histones. Scientific Reports


LaRock C, Todd J, LaRock D, Olson J, O’Donoghue A, Robertson A, Cooper M, Hoffman H, Nizet VIL-1β is an innate immune sensor of microbial proteolysis. Science Immunology

▪︎  Science Immunology "A one-protein signaling pathway in the innate immune system" by M Orzalli & J Kagan 

▪︎  Nature Reviews Immunology “IL-1beta activation under scrutiny” 

▪︎  Science “A new trick for IL-1beta” 

▪︎  UCSD press “Flesh-eating infections in arthritis patients spur discovery” 

▪︎  San Diego Union-Tribune “How flesh-eating bacteria evade immune response”


LaRock C, Nizet V. Inflammasome/IL-1beta responses to streptococcal pathogens. Frontiers Immunology

LaRock C, Döhrmann S, Todd J, Corriden R, Johannssen T, Lepenies B, Gallo R, Ghosh P, Nizet V. Group A streptococcal M1 protein sequesters cathelicidin to evade innate immune killing. Cell Host & Microbe

▪︎  Cell Host & Microbe preview "Streptococcal M1 Strikes by Neutralizing Cathelicidins" by B Henriques-Normark & S Normark 

▪︎  UCSD press "Deadly bacteria stiff-arm the immune system"

LaRock C, Nizet V. Cationic antimicrobial peptide resistance mechanisms of streptococcal pathogens. BBA Biomembranes


Barnett T, Liebl D, Seymour L, Gillen C, Lim J, LaRock C, Davies M, Schulz B, Nizet V, Teasdale R, Walker M. The globally disseminated M1T1 clone of group A Streptococcus evades autophagy for intracellular replication. Cell Host & Microbe

▪︎  Cover feature

▪︎  Cell Host & Microbe preview "S. pyogenes Escapes Autophagy" by I Nakagawa

LaRock C, Cookson B. Burning down the house: cell actions during pyroptosis. PLoS Pathogens

LaRock C, Yu J, Horswill A, Parsek M, Minion F. Transcriptome analysis of acyl-homoserine lactone based quorum sensing regulation in Yersinia pestis. PLoS One

2012 & Earlier

LaRock C, Cookson B. The Yersinia virulence effector YopM binds caspase-1 to arrest inflammasome assembly and processing. Cell Host & Microbe 2012

▪︎  Cover feature

▪︎  Cell Host & Microbe preview "YopM Puts Caspase-1 on Ice" by I Jørgensen & E Miao 

▪︎  UW press "Dark Ages scourge enlightens modern struggle between man & microbe" 

▪︎  Faculty of 1000: 3

Livny J, LaRock C, Friedman D. Identification and isolation of lysogens with induced prophage. Methods in Molecular Biology. 2009

Tchesnokova V, Aprikian P, Yakovenko O, LaRock C, Kidd B, Vogel V, Thomas W, Sokurenko E. Integrin-like allosteric properties of the catch bond-forming FimH adhesin of Escherichia coli. The Journal of Biological Chemistry. 2008

Held K, LaRock C, D'Argenio D, Berg C, Collins C. A metalloprotease secreted by the insect pathogen Photorhabdus luminescens induces melanization. Applied & Environmental Microbiology. 2007