Hao-Han Pang (龎浩翰)

Collaborator

Lab of Recombinant Nano-biomaterials Applications (Lab of R.N.A.)

Official Website：https://sites.google.com/view/labofrna

Research gate: https://www.researchgate.net/profile/Hao_Han_Pang2

Education：

PhD, Biomedical Sciences, NSYSU, Taiwan

Master of science, Medical Science and Technology, NSYSU, Taiwan

Experience：

2025-          Assistant Researcher, CGUST, Taiwan

2023-2025 Postdoctoral Scientist, Nationwide Children's Hospital, USA

2022-2023 Postdoctoral fellow, Department of Biomedical Engineering , NCKU, Taiwan

2021- 2022 Postdoctoral fellow, Institute of Medical Science and Technology, NSYSU, Taiwan

2019-2021 Research assistant, NSYSU, Taiwan

2015-2019 Research assistant, Chang Gung Memorial Hospital, Taiwan

Expertise

Nanotechnology, 

biosensors, 

Virus-like particles application,

Fluorescent RNA / RNAi / drug delivery system

Awards

• Dr. Zhao-ren Li Biomedical Engineering and Development Foundation Young Investigator Award

• Best Yang Scholar Oral Presentation Second Prize in International Conference on Precision Nanomedicine in Theranostics & the 2022 Annual Meeting of Taiwan Nanomedicine Society.

• The Excellent Student oral Presentation Award in 2020 ICSS 

• Young Investigator Award for Pediatric Neuropsychiatric Science, Research of Excellence (2020). 

• The best Student Poster Presentation Award in 2020 BCRS. 

• The Excellent Student Oral Presentation Award in 2019 IADDS-BCRS. 

Publications

2024

10. H.H Pang, N.S Li, Y.P. Hsu, S.P. Ju, G.D. Syu, P.X. Du, C.Y. Huang, K.C. Wei*, H.W. Yang*. AI-Driven Design System for Fabrication of Inhalable Nanocatchers for Virus Capture and Neutralization. Advanced Healthcare Materials, Volume 13, Issue 5, 2302927 (2024). (IF = 10.0)  [Cover]

2023

9. H. H. Pang, C. Y. Huang, P. Y. Chen, N. S. Li, Yi. P. Hsu, J. K. Wu, H. F. Fan, K. C. Wei* and H.W. Yang*. Bioengineered bacteriophage-like nanoparticles as RNAi therapeutics to enhance radiotherapy against glioblastomas. ACS Nano, 2023, 17, 11, 10407–10422 (2023). (IF=18.072) [Cover]

2022

8. Y.J. Chen, Y.P. Hsu, Y.L. Tain, N.S. Li, H.H. Pang, S.W. Kuo*, H.W. Yang*. Microneedle patches integrated with lateral flow cassettes for blood-free chronic kidney disease point-of-care testing during a pandemic. Biosensors and Bioelectronics 208, 114234 (2022). (IF = 10.618)

2021

7. W.H. Chen, K.J. Yu, J.W. Jhou, H.H. Pang, W.H. Weng, W.S. Lin*, and H.W. Yang*. Glucose/glutathione co-triggered tumour hypoxia relief and chemodynamic therapy to enhance photothermal therapy in bladder cancer. ACS Applied Bio Materials (2021).

2020

6. H.H. Pang, Y.C. Ke, N.S. Li, Y.T. Chen, C.Y. Huang, K.C. Wei*, H.W. Yang*. A new lateral flow plasmonic biosensor based on gold-viral biomineralized nanozyme for on-site intracellular glutathione detection to evaluate drug-resistance level. Biosensors and Bioelectronics 165, 112325 (2020). (IF = 10.618)

5. N.S. Li, Y.T. Chen, Y.P. Hsu, H.H. Pang, C.Y. Huang, Y.L. Shiue, K.C. Wei*, H.W. Yang*. Mobile healthcare system based on the combination of lateral flow pad and smartphone for rapid detection of uric acid detection in whole blood. Biosensors and Bioelectronics 164,112309. (2020). (IF = 10.618)

4. Y.P. Hsu, H.W. Yang*, N.S. Li, Y.T. Chen, H.H. Pang, S.T. Pang*. Instrument-Free Detection of FXYD3 Using Vial-Based Immunosensor for Earlier and Faster Urothelial Carcinoma Diagnosis. ACS Sensors 5,928-935 (2020).  (IF = 7.711)

3. Y.P. Hsu, N.S. Li, Y.T. Chen, H.H. Pang, K.C. Wei, H.W. Yang*. A serological point-of-care test for Zika virus detection and infection surveillance using an enzyme-free vial immunosensor with a smartphone. Biosensors and Bioelectronics 151, 111960 (2020). (IF = 10.618)

2019

2. H.H. Pang, C.Y. Huang, Y.W. Chou, C.J. Lin, Z.L. Zhou, Y.L. Shiue, K.C. Wei*, H.W. Yang*. Bioengineering fluorescent virus-like particle/RNAi nanocomplexes act synergistically with temozolomide to eradicate brain tumors. Nanoscale, 11, 8102-8109 (2019). (IF =7.790)

1. H.H. Pang, P.Y. Chen, K.C. Wei, C.W. Huang, Y.L. Shiue, C.Y. Huang*, H.W. Yang*. Convection-enhanced delivery of a virus-like nanotherapeutic agent with dual-modal imaging for besiegement and eradication of brain tumors. Theranostics 9, 1752-1763 (2019). (IF = 11.556) [Inside Front Cover]

PATENTS

•  Fusion Peptide for Forming Virus-Like Particle

[TW202214670A, US20220098236A1, CN114276459A]

Inventors: Hong-Wei Yang, Hao-Han Pang, Ying-Pei Hsu, Nan-Si Li.

•  Method for Manufacturing Biosensor and Biosensor Manufactured by the Same 

 [US20 220099616A1, CN114279980A]

Inventors: Hong-Wei Yang, Hao-Han Pang, Ying-Pei Hsu, Nan-Si Li.

Conferences

7. H. H. Pang, N. S. Li, Y. P. Hsu, H. W. Yang* (2022, Sep). Fighting virus using virus: application of virus-like particle-based SARS-CoV-2 inhibitor for COVID-19 infection reducing and potential in treatment. 2022 Annual Meeting of Biomaterials and Controlled Release Society in Taiwan. 

6. H.H. Pang, C.W. Huang, K.C. Wei, H.W. Yang* (2022, Jul).Real-time traceable three-way junction RNA virus-like particles to enhanceradiotherapy by multi-gene silencing in glioblastoma. International Conferenceon Precision Nanomedicine in Theranostics & the 2022 Annual Meeting of Taiwan Nanomedicine Society, Hsinchu, Taiwan.

5. H.H. Pang, H.W. Yang* (2020, Oct). Rapid detection of intracellular glutathione (GSH) to predict drug-resistance level based on gold-viral biomineralized nanozyme integrated PAD with online auto-analysis system. International Conference on Smart Sensors.

4. H.H. Pang, H.W. Yang* (2020, Aug). Gene Editing Bacterial Phage Based Biological Platforms for Chemo-Gene Therapy in Glioblastoma. 2020 Annual meeting of Biomaterials and Controlled Release Society in Taiwan.

3. N.S. Li, H.H. Pang, Y.P. Hsu, H.W. Yang* (2019, Jun). A Viral-Based Peroxidase-Like Gold Nano-Cluster Complex as Biosensor for Chemoresistance Prediction of Glioma Cells. 2019 International Conference on Smart Sensors. 2019 International Conference on Smart Sensors, Hsinchu, Taiwan.

2. H.H. Pang, C.Y. Huang, Y.L. Shiue, K.C. Wei, H.W. Yang* (2019, Mar). Fluorescent virus-like particle/ RNAi nanocomplexes act synergistically with temozolomide to eradicate brain tumors. 2019 International Advan CED Drug Delivery Symposium & Annual Meeting of Biomaterials and Controlled Releases Society in Taiwan.

1. H.H. Pang, P.Y. Chen, H.W. Yang* (2018, Sep). Epirubicin-loading fluorescent Qβ virus-like particles incorporated with CED for brain tumor therapy. 16th World Medical Nanotechnology Congress, Japan, Radisson Narita. Oral presentation.