Aruncus dioicus / Geitenbaard

De geitenbaard (Aruncus dioicus) is een vaste plant uit de rozenfamilie (Rosaceae). De plant wordt 1,5–2 m hoog. De soort heeft weinig vertakte stengels. De bladeren zijn onevengeveerd.
De plant is tweehuizig: de bloemen zijn geelwit bij vrouwelijke pluimen en helderwit bij mannelijke. De bloei is van juni tot half augustus. De opmerkelijke naam heeft betrekking op de bloeiwijze met sterk vertakte pluimen met crème-witte bloemen, die doet denken aan de sik van een geit.

Aruncus dioicus (Walter) Fern. Familie Rosaceae. 
Bladen dubbel geveerd, tot 1 m lang, zonder steunblaadjes, blaadjes eirond, spits, scherp gezaagd. Bloeiwijze groot, wijd pluimvormig. Bloemen meestal eenslachtig. Kroonbladen (geelachtig) wit, ca. 3 mm lang. Meeldraden veel. Vruchtbeginsels 3, vrij. 

Hoogte bloeiende plant: 1,00-2,00 m.
Bloeitijd: juni.
Levensvorm: Hemikryptofyt.

Gebruik: In Italië worden de jonge geitenbaardscheuten als delicatesse gegeten; ze worden gekookt en samen met eieren en kaas gegeten. In een ander deel van Italië doet men de scheuten door de soep.



J Nat Med. 2012 Oct;66(4):631-6. doi: 10.07/s11418-012-0633-3. Epub 2012 Feb 17.
Potent anti-aging activity of Aruncus dioicus, a native plant of Ulleung-do, South Korea, in CCD-986sk fibroblasts via suppression of matrix metalloproteinases. Kim DH1, Moon YS, An BJ, Son JH.
Aruncus dioicus var. kamtschaticus HARA, also known as goat's beard, is a native plant in Ulleung-do, South Korea. It has been used as a remedy in skin care, detoxification, blood stanching, tonsillitis. High performance liquid chromatography with diode array detection was used for partial validation of bioactive chemicals in A. dioicus ethyl acetate (EtOAc) extract, and EtOAC extract was examined for its effect on ultraviolet (UV)-induced cell aging using CCD-986sk-human skin fibroblast cells. Cells were exposed to UV-B for 1 min before extract treatment. An established viability assay was performed to test cell toxicity of A. dioicus at 5, 10, or 50 μg/ml concentrations, and activities of matrix metalloproteinase (MMP) 1, 2, 3, phosphorylated-p38 (p-p38, an activated form of p38), p38, and c-fos transcription factors were evaluated. A. dioicus extract decreased the amount of mRNA transcripts and total proteins of MMP1, 2, 3 as well as p-p38 and c-fos. The c-fos expression was also confirmed by in vivo fluorescent staining of CCD-986sk cells after UV-B exposure followed by EtOAc extract treatment. The results showed that expression of skin aging related genes encoding MMP1, 2, and 3 was inhibited by reduced transcription factor expression of p-p38 and c-fos by A. dioicus EtOAc extract. The results suggest that A. dioicus extract can be used to reduce UV-B-induced skin aging and is a potential candidate for cosmedical materials.



Effect of Aruncus dioicus var. kamtschaticus Extract on Neurodegeneration Improvement: Ameliorating Role in Cognitive Disorder Caused by High-Fat Diet Induced Obesity
Su Bin Park 1,†, Jin Yong Kang 1,†, Jong Min Kim 1, Seon Kyeong Park 1, Seul Ki Yoo 1, Uk Lee 2, Dae-Ok Kim 3OrcID and Ho Jin Heo 1,*OrcID
Su Bin Park and Jin Yong Kang contributed equally to this work as co-first authors.
Nutrients 2019, 11(6), 1319; https://doi.org/10.3390/nu11061319
Received: 2 May 2019 / Revised: 4 June 2019 / Accepted: 11 June 2019 / Published: 12 June 2019
(This article belongs to the Special Issue Nutrition, Cognition and Brain Integrity)

This study was performed to estimate the possibility of using an ethyl acetate fraction from Aruncus dioicus var. kamtschaticus (EFAD) on metabolic syndrome that is induced by a high-fat diet (HFD). It was demonstrated that EFAD suppresses lipid accumulation and improves insulin resistance (IR) caused by Tumor necrosis factor alpha (TNF-α) in in-vitro experiments using the 3T3-L1 cell. In in-vivo tests, C57BL/6 mice were fed EFAD at 20 and 40 mg/kg body weight (BW) for four weeks after the mice were fed HFD for 15 weeks to induce obesity. EFAD significantly suppressed the elevation of BW and improved impaired glucose tolerance in obese mice. Additionally, this study showed that EFAD has an ameliorating effect on obesity-induced cognitive disorder with behavioral tests. The effect of EFAD on peripheral-IR improvement was confirmed by serum analysis and western blotting in peripheral tissues. Additionally, EFAD showed an ameliorating effect on HFD-induced oxidative stress, impaired cholinergic system and mitochondrial dysfunction, which are interrelated symptoms of neurodegeneration, such as Alzheimer’s disease and central nervous system (CNS)-IR in brain tissue. Furthermore, we confirmed that EFAD improves CNS-IR by confirming the IR-related factors in brain tissue. Consequently, this study suggests the possibility of using EFAD for the prevention of neurodegeneration by improving metabolic syndrome that is caused by HFD. 



Onderzoeken
  • Koreaans onderzoek 2011: http://www.ncbi.nlm.nih.gov/pubmed/2154625
  • Koreaans onderzoek 2012: http://www.ncbi.nlm.nih.gov/pubmed/24471070
  • Koreaans onderzoek 2012: http://www.ncbi.nlm.nih.gov/pubmed/22350144

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