Our lab works on the entry and exit pathways of enveloped (membrane-coated) viruses in their host cells. All enveloped viruses use membrane fusion to infect a cell, and membrane budding to produce new viruses. Studying these entry and exit processes helps us to understand the mechanisms of virus infection and to develop new antiviral therapies, and also provides a key model for cellular membrane fusion and budding reactions. Our research focuses primarily on alphaviruses and flaviviruses, virus groups that include important human pathogens such as dengue, West Nile, and yellow fever viruses. 

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to learn more about our research, papers, and training in the Kielian lab.

Recent News:

* Welcome our new Ph.D. student, Criselda Dillague, and our new Postdoctoral IRACDA/BETTR Scholar, Dr. Elisa Frankel!

* Congratulations to Dr. Rebecca Brown, who has been awarded the Charles H. Revson Senior Fellowship in Biomedical Sciences (2018-2020)!

* We published a new review: Brown, R. S., Wan, J. J., and Kielian, M. (2018) "The alphavirus exit pathway: What we know and what we wish we knew." Viruses 10(2), 89: doi:10.3390 / v10020089.