Structure Gallery

Crystal Structure of the SMK box (SAM-III) Riboswitch

EM structure of the Yeast exosome-Rrp44

Cystal structure of the archaeal exosome

PDB ID: 3E5C (Complex with SAM), 3E5E (SAH), 3E5F (Se-SAM)

Lu C, Smith AM, Fuchs RT, Ding F, Rajashankar K, Henkin TM, Ke A.

Nature Structural & Molecular Biology. 2008 May;15:1076-1083.

Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing.

Wang HW, Wang J, Ding F, Callahan K, Bratkowski MA, Butler JS, Nogales E, Ke A.

Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16844-9.

Crystal Structure of the yitJ S Box/SAM-I Riboswitch

Related article:

Crystal Structure of the tetrameric pRNA ring

Lu C, Ding F, Ke A.

PLOS One. 2010 Jan 15;5(1):e8739.

PDB ID: 3L7Z

PDB ID: 3NPB

Lu C, Ding F, Chowdhury A, Pradhan V, Tomsic J, Holmes WM, Henkin TM, Ke A.

J Mol Biol. 2010 Dec 17;404(5):803-18.

Crystal Structure of CRISPR-associated Csn2

Crystal Structure of CRISPR-associated Cas5d

PDB ID: 3R4F

Ding F, Lu C, Zhao W, Rajashankar KR, Anderson DL, Jardine PJ, Grimes S, Ke A.

Proc Natl Acad Sci U S A. 2011 May 3;108(18):7357-62.

Crystal structure of clustered regularly interspaced short palindromic repeats (CRISPR)-associated Csn2 protein revealed Ca2+-dependent double-stranded DNA binding activity.

Nam KH, Kurinov I, Ke A.

J Biol Chem. 2011 Sep 2;286(35):30759-68.

PDB ID: 3S5U

Related article:

Crystal Structure of CRISPR-associated Cas2

PDB ID: 4F3M

Nam KH, Haitjema C, Liu X, Ding F, Wang H, Delisa MP, Ke A.

Structure. 2012 Jul 24.

Crystal Structure of CRISPR-associated CasB

Double-stranded Endonuclease Activity in B. halodurans Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Cas2 Protein.

Nam KH, Ding F, Haitjema C, Huang Q, Delisa MP, Ke A.

J Biol Chem. 2012 Aug 31.

PDB ID: 4ES1, 4ES2, 4ES3

Related article:

Crystal Structure of CRISPR-associated CasB

PDB ID: 4H79

Related article:

Nucleic Acid Binding Surface and Dimer Interface Revealed by CRISPR-associated CasB Protein Structures.

Nam KH, Huang Q, Ke A*.

FEBS Letters. 2012.

PDB ID: 4H7A

Related article:

Nucleic Acid Binding Surface and Dimer Interface Revealed by CRISPR-associated CasB Protein Structures.

Nam KH, Huang Q, Ke A*.

FEBS Letters. 2012.