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Arguably, drug research has contributed more to the progress of medicine during the past decades than any other scientific factor. One of the main areas of drug research is related to the analysis of proteins.
The world of pharmacology is becoming increasingly dependent on the advances in the fields of genomics and proteomics, which brings about the challenge of finding robust methods to analyze the complex data they generate. 
Such challenge takes us towards approaches under the conceptual umbrella of artificial intelligenceincluding machine learning, statistical pattern recognition and soft computing. Statistical machine learning methods for the analysis of protein sequences are at the core of the current project.
More than 50% of drugs target only four key protein families, from which almost a 30% correspond to the G-Protein Coupled Receptors (GPCR) superfamily. This superfamily regulates the function of most cells in living organisms and is the goal of the current project. 
The automatic grouping and classification of GPCRs into families and these into subtypes based on sequence analysis may significantly contribute to ascertain the pharmaceutically relevant properties of GPCRs.
For further information, visit the Project Definition page.

Messages

  • Doctors to be The two PhD projects associated to KAPPA-AIM, carried out by our students Martha Ivón Cárdenas and Caroline König, are advancing at full speed and we expect completion of both ...
    Posted Sep 17, 2015, 5:03 AM by Alfredo Vellido
  • Into the future ... Despite the scant funding allocated to KAPPA-AIM, we have managed to pull ourselves through and achieve significant results and a solid corpus of publications.These results have ...
    Posted Sep 17, 2015, 4:57 AM by Alfredo Vellido
  • Beta disclaimer As you can see, this is still a beta version of the KAPPA-AIM web ... bear with us until we get it properly up-and-running ...
    Posted Sep 23, 2013, 7:17 AM by Alfredo Vellido
  • Welcome to our brand new web... Long time due (about 9 months now), but better late than never, this is the 'official' website of our KAPPA-AIM project (Knowledge acquisition in PharmacoProteomics using Artificial Intelligence Methods ...
    Posted Sep 23, 2013, 7:14 AM by Alfredo Vellido
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