Membrane Biosynthesis, Structure & Behavior in Bacterial Pathogenesis


Welcome to the research lab of Jessica C. Seeliger, Assistant Professor in the Department of Pharmacological Sciences in the School of Medicine at Stony Brook University

We are applying biochemical, microbiological and biophysical methods to fundamental questions in bacterial membrane biogenesis as they relate to Mycobacterium tuberculosis, the bacterium that causes tuberculosis. We are also developing genetic and biochemical tools to regulate gene expression and to characterize cell envelope-associated processes in mycobacteria.

  • How is lipid biosynthesis accomplished at the cytosol-membrane interface?
  • What are the molecular mechanisms underlying bacterial membrane assembly?
  • How can we subvert lipid biosynthesis and membrane assembly pathways for antimicrobial therapy?

The JSeeliger Lab welcomes students from the MCP, Chemistry, Microbiology, MCB and BSB graduate programs.

Interested learning more about the lab?  Please contact Prof. Seeliger at or 631-632-1674.

JSeeliger Lab gratefully acknowledges support from

HTML Counter

4.18.2017 Catching up with our amazing undergrads! Congratulations to Amgad on being awarded a URECA Summer Research Fellowship, Rebecca on her Provost Award for Academic Excellence, and Kathryn on her Undergraduate Recognition Award for Academic Excellence. Way to go!

3.13.2017 Congratulations to Adrian Chen from Great Neck South High School on being accepted to the Simons Summer Research Program! Adrian will join the lab in Summer 2017. 

3.9.3017 Congratulations to Meg, Erik, Lulu and Jia on their co-authored paper in ACS Infectious Diseases. Go team!

1.16.2017 A belated welcome to our new research  undergrad, Amgad Ghoprial, a sophomore biology major.

1.13.2017 Congratulations to Dr. Meg on her review on mycobacterial outer membrane lipid transport in BBA Molecular and Cell Biology of Lipids!

1.3.2017 Happy new year and congratulations to Erik on his paper on riboswitches in the Journal of Bacteriology!