Membrane Biosynthesis, Structure & Behavior in Bacterial Pathogenesis


Welcome to the research lab of Jessica C. Seeliger, Assistant Professor in the Department of Pharmacological Sciences in the School of Medicine at Stony Brook University

We are applying biochemical, microbiological and biophysical methods to fundamental questions in bacterial membrane biogenesis as they relate to Mycobacterium tuberculosis, the bacterium that causes tuberculosis. We are also developing genetic and biochemical tools to regulate gene expression and to characterize cell envelope-associated processes in mycobacteria.

  • How is lipid biosynthesis accomplished at the cytosol-membrane interface?
  • What are the molecular mechanisms underlying bacterial membrane assembly?
  • How can we subvert lipid biosynthesis and membrane assembly pathways for antimicrobial therapy?

The JSeeliger Lab welcomes students from the MCP, Chemistry, Microbiology, MCB and BSB graduate programs.

Interested learning more about the lab?  Please contact Prof. Seeliger at or 631-632-1674.

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5.18.2016 Hiren has defended his thesis and been hooded! Congratulations, Dr. Patel!!! Photos of both defense and graduation celebrations here. 

4.25.2016 Congratulations to Rebecca on winning a scholarship Brookhaven National Lab that recognizes "the academic achievements of WISE students for their excellence in research."

4.14.2016 Congratulations to Kathryn on winning a URECA Summer Research fellowship to support her work in the lab this summer.

3.15.2016 Congratulations to Melody on her acceptance the Simons Summer Research Program for high school students, through which she will do research in our lab again this summer.

1.25.2016 Welcome to our new undergraduate researcher and biochemistry major Kathryn Eckartt.

1.12.2016 Happy new year and congratulations to Lulu on her co-authored paper in PLoS Pathogens!

8.13.2015 Congratulations to Meg on her paper in Biochemistry!

7.27.2015 Meg has defended her thesis. Congratulations, Dr. Touchette!!! Photos of the celebration here.