Membrane Biosynthesis, Structure & Behavior in Bacterial Pathogenesis


Welcome to the research lab of Jessica C. Seeliger, Assistant Professor in the Department of Pharmacological Sciences in the School of Medicine at Stony Brook University

We are applying biochemical, microbiological and biophysical methods to fundamental questions in bacterial membrane biogenesis as they relate to Mycobacterium tuberculosis, the bacterium that causes tuberculosis. We are also developing genetic and biochemical tools to regulate gene expression and to characterize cell envelope-associated processes in mycobacteria.

  • How is lipid biosynthesis accomplished at the cytosol-membrane interface?
  • What are the molecular mechanisms underlying bacterial membrane assembly?
  • How can we subvert lipid biosynthesis and membrane assembly pathways for antimicrobial therapy?

The JSeeliger Lab welcomes students from the MCP, Chemistry, Microbiology, MCB and BSB graduate programs.

Interested learning more about the lab?  Please contact Prof. Seeliger at or 631-632-1674.

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1.12.2016 Happy new year and congratulations to Lulu on her co-authored paper in PLoS Pathogens!

8.13.2015 Congratulations to Meg on her paper in Biochemistry!

7.27.2015 Meg has defended her thesis. Congratulations, Dr. Touchette!!! Photos of the celebration here. 

7.6.2015 Welcome to high school student Melody Yang, who comes to us from Great Neck South High School.

6.1.2015 Welcome to postdoctoral fellow Uday Ganapathy. Uday comes to us from Weill Cornell, where he did his thesis work in the Ehrt lab.

5.21.2015 Many congratulations to our graduates Peter, Julia and Meg! Much fun was had by lab, family and friends at the doctoral hooding, departmental ceremony and lab party.