Membrane Biosynthesis, Structure & Behavior in Bacterial Pathogenesis


Welcome to the research lab of Jessica C. Seeliger, Assistant Professor in the Department of Pharmacological Sciences in the School of Medicine at Stony Brook University

We are applying biochemical, microbiological and biophysical methods to fundamental questions in bacterial membrane biogenesis as they relate to Mycobacterium tuberculosis, the bacterium that causes tuberculosis. We are also developing genetic and biochemical tools to regulate gene expression and to characterize cell envelope-associated processes in mycobacteria.

  • How is lipid biosynthesis accomplished at the cytosol-membrane interface?
  • What are the molecular mechanisms underlying bacterial membrane assembly?
  • How can we subvert lipid biosynthesis and membrane assembly pathways for antimicrobial therapy?

The JSeeliger Lab welcomes students from the MCP, Chemistry, Microbiology, MCB and BSB graduate programs.

Interested learning more about the lab?  Please contact Prof. Seeliger at or 631-632-1674.

JSeeliger Lab gratefully acknowledges support from

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1.13.2017 Congratulations to Dr. Meg on her accepted review on mycobacterial outer membrane lipid transport in BBA Molecular and Cell Biology of Lipids!

1.3.2017 Happy new year and congratulations to Erik on his paper on riboswitches in press in the Journal of Bacteriology!

11.1.2016 Welcome to Jia Kim, an MS student in the Molecular and Cellular Pharmacology program.

10.25.2016 Congratulations, Uday, on garnering an Outstanding Presentation Prize at the NYAS Emerging Paradigms in Chemical Biology and Drug Discovery meeting. See the prizewinner here.

6.1.2016 Good luck, Dr. Patel and Dr. Touchette! As our first PhD graduates move on, we wish them the best in the clinic and in their future research endeavors!

5.30.2016 Welcome to Michael Li, an MSTP student who is starting his PhD in Molecular and Cellular Pharmacology.

5.18.2016 Hiren has defended his thesis and been hooded! Congratulations, Dr. Patel!!! Photos of both defense and graduation celebrations here.