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Dr. Jiandi Wan

jdween@rit.edu

Microsystems Engineering, Rochester Institute of Technology, Rochester, NY 14623.

Office: 17-2159; Office phone: 585-475-7726

Education

PhD. Boston University, Boston, MA, USA. 2001-2006.

B.S & M.S. Wuhan University, Wuhan, P.  R. China. 1994-2001.

Research Experience

Research Associate, Princeton University. 2009-2012.

Postdoctoral Fellow, Harvard University. 2006-2009.

Professional services

Member of the Organization Committee for 2012 International Conference & Exhibition on Nanotechnology and Nanomedicine. March 2-14, 2012, Omaha, USA. Editorial board member of the Central European Journal of Engineering and International Journal of Materials and Chemistry.

Reviewer to Nanoscale, Annals of Biomedical Engineering, Journal of Biomedical Optics, Biomedical Optics Express, Chemical Communications, Journal of Materials Chemistry, Small, Advanced Functional Materials, Lab on Chip, Soft Matter, Applied Surface Science, Journal of Visualized Experiments, Physica B, and book proposal of Bioinspiration, Biomimetics, and Bioreplication: Developments in Engineered Biomimicry.

Publications

1.      Chen, H., Li, J., Wan, J., Weitz, D. A., and Stone, H. A. Gas-core triple emulsions for ultrasound controlled release. Small. Submitted.

2.      Tsai, S. S. H., Wexler, J. S., Wan, J, and Stone, H. A. Microfluidic ultralow interfacial tensiometry by magnetic forcing. Lab on chip. Submitted.

3.      Forsyth, A. M., Braunmüller, S., Wan, J., Franke, T., Stone, H. A. (2012) The effects of membrane cholesterol and simvastatin on red blood cell deformability and ATP release. Microvasc Res. Accepted.

4.      Wan, J., and Stone, H. A. (2012) Coated gas bubbles for the continuous synthesis of hollow inorganic particles. Langmuir. 28, 37–41.

5.      Wan, J., Forsyth, A. M., and Stone, H. A. (2011) Red blood cell dynamics: from cell deformation to adenosine-5'-triphosphate release. Integr. Biol. 3, 972-981. Invited Review. 

6.      Tsai, S. S. H., Wexler, J. S., Wan, J, and Stone, H. A. (2011) Conformal coating of particles In microchannels by magnetic forcing. Applied Physics Letter. 99, 153509.

7.      Forsyth A. M., Wan, J., Owrutsky, P.D., Abkarian, M., and Stone, H. A. (2011) A multiscale approach to link red blood cell dynamics, shear viscosity, and ATP release. Proc. Nat. Acad. Sci. USA, 108, 10986-10991.

8.      Chen, H., Zhao, Y., Li, J., Guo, M., Wan, J., Weitz, D. A., Stone, H. A. (2011) Flow-controlled coalescence inside droplets: reactions in double emulsions. Lab on Chip. 11, 2312-2315.

9.      Xia, B., Gerard, B., Solano, D.M., Wan, J., Jones, G., Porco, J. A. (2011) ESIPT-mediated photocycloaddtions of 3-hydroxyquinolinones: development of a fluorescence quenching assay for reaction screening. Org. Lett. 13, 1346–1349.

10.  Subramaniam, A. B., Wan, J., Gopinath, A., and Stone, H. A. (2011) Clay vesicles: Properties and emergent compartmentalization in a self-assembling system. Soft Matter. 7, 2600–2612.

11.  Wan, J., and Stone, H. A. (2010) Microfluidic generation of a high volume fraction of bubbles in droplets. Soft Matter. 6, 4677-4680. Cover Story.

12.  Forsyth, A. M., Wan, J., Ristenpart, W. D., and Stone, H. A. (2010) The dynamic behavior of chemically “stiffened” red blood cells in microchannel flows. Microvasc Res.  80, 37-43.

13.  Wan, J., Thomas, M., and Vullev, V. I. (2009) Surface bound proteins with preserved functionality. Ann. Biomed. Eng. 37, 1190-1205.

14.  Hu, J., Xia, B., Bao, D., Ferreira, A., Wan, J., Jones II, G., and Vullev, V. I. (2009) Long-lived photogenerated states of α-oligothiophene-acridinium dyads have triplet character. J. Phys. Chem. A 113, 3096-3107.

15.  Stone, H.A., Forsyth, A. M., and Wan, J. (2009) Slipping through blood flow. Physics 2, 89.

16.  Wan, J., Ristenpart, W. D., and Stone, H. A. (2008) Dynamics of shear-induced ATP release from red blood cells. Proc. Nat. Acad. Sci. USA. 105, 16432-16437.

17.  Wan, J., Bick, A., Sullivan, M., and Stone, H. A. (2008) Controllable microfluidic production of microbubbles in water-in-oil emulsions and the formation of porous microparticles. Adv. Mater. 20, 3314-3318.

18.  Wan, J., Ferreira, A., Xia, W., Chow, C. H.,  Takechi, K., Kamat, P. V., Jones II, G., and Vullev, V. I. (2008) Solvent dependence of the charge-transfer properties of a quaterthiophene-anthraquinone dyad. J. Photochem. Photobiol. A: Chem. 197, 364-374.

19.  Ristenpart, W. D., Wan, J., and Stone, H. A. (2008) Enzymatic reactions in microfluidic devices. Anal. Chem. 80, 3270-3276.

20.  Ristenpart, W. D., Kim, P. G., Donmingues, C., Wan, J., and Stone, H. A. (2007) Influence of substrate conductivity on circulation reversal in evaporating drops. Phys. Rev. Lett. 99, 234502.

21.  Jones II, G., Yan, D., Hu, J., Wan, J., Xia, B., and Vullev, V. I. (2007) Photoinduced electron transfer in arylacridinium conjugates in a solid glass matrix. J. Phys. Chem. B 111, 6921 – 6929.

22.  Vullev, V. I., Wan, J., Heinrich, V., Landsman, P., Bower, P. E., Xia, B.,  Millare, B., and Jones II, G. (2006) Nonlithographic fabrication of microfluidic devices. J. Am. Chem.  Soc. 128, 16062-16072.

23.  Gartner, C. A., Wen, B., Wan, J., Becker, R. S., Jones II, G., Gygi, S. P., and Nelson, S. D. (2005) Photochromic agents as tools for protein structure study: lapachenole is a photoaffinity ligand of cytochrome P450 3A4. Biochemistry 44, 1846-1855.

24.  Wan, J., Feng, Y., Hu, Y., Da, S., and Wang, Z. (2002) Preparation and evaluation of 2, 4, 6-trinitrophenol-modified zirconia-alumina for high performance liquid chromatography and its application in the separation of fullerenes. Chemical Journal of Chinese Universities-Chinese, 23, 1259-1263.

25.  Hu, Y., Feng, Y., Wan, J., and Da, S. (2002) Comparison of Lewis acid modified mixed-oxide as chromatographic packings in reversed-phase chromatography. J. Liq. Chrom. & Rel. Technol., 25, 83-99.

26.  Hu, Y., Feng, Y., Wan, J., Da, S., and Hu, L. (2001) Native and stearic acid modified ceria-zirconia supports in normal and reversed-phase HPLC. Talanta, 54, 79-88.

27.  Wan, J., Feng, Y., Hu, Y., Da, S., and Wang, Z. (2001) Preparation and evaluation of zirconia-alumina composites for high performance liquid chromatography. Chin. J. Anal. Chem.-Chinese 29, 802-805.

28.  Wan, J., Feng, Y., Hu, Yu., Da, S., and Wang, Z. (2001) Preparation and evaluation of acid-corroded zirconia-alumina composites as HPLC support. Journal of Analytical Science-Chinese. 17, 371-374.

29.  Wan, J., Feng, Y., Hu, Y., Da, S., and Wang, Z. (2001) Preparation of mesopore zirconia-alumina composite and its application to normal HPLC support. Chemical Journal of Chinese Universities-Chinese, 22, 1661-1663.

Conference Proceedings and Presentations

1.      “Solvent dependence of the charge-transfer properties of a quaterthiophene-anthraquinone dyad” Gordon Research Conference, Electron donor-acceptor interactions. Newport, Rhode Island, August 3, 2010.

2.      “Surface-bound proteins with preserved functionality” NSF/ACS Fellowship for Faraday Discussion 146.  Richmond, Virginia, April 9, 2010.

3.       “Probing the cellular dynamics: a microfluidic study of ATP release from red blood cells” Squishy Physics, Harvard University. September 9, 2009.

4.      “Controllable microfluidic production of microbubbles in water-in-oil emulsions and the formation of porous microparticles” Partnerships for Research and Education in Materials (PREM) Workshop, School of Engineering and Applied Sciences, Harvard University.  June 24, 2009; AIChE Annual Meeting, Philadelphia, PA, November 18, 2008.

5.      Wan, J., Sullivan, M., and Stone, H. A. (2007) Controllable production of gas/water/oil double emulsions in microfluidic devices. Proceedings of the First Shenyang International Colloquium on Microfluidics. 213-214.

6.      Thomas, M., Wan, J., and Vullev, V. I. (2007) Biofunctionalization of silica-based substrates.  Lamego, 21-23.

7.      “Generation of Mono-dispersed oil/water/gas Emulsions in Microfluidic System” Shenyang International Colloquium on Microfluidics, Shenyang, China, October 23, 2007.

8.      “A Microfluidic Approach for Studying Shear-induced ATP Release Kinetics from Red Blood Cells” APS-DFD Meeting, Salt Lake City, November 19, 2007; AIChE Annual Meeting, Salt Lake City, November 8, 2007.

9.      Wan, J., Landsman, P., Xia, B., Bower, P., Heinrich, V., Jones II, G., and Vullev, V. I. (2006) Continuous-flow microfluidic devices for detection of bacterial endospores.  Proc. NanoBio, 5, 1.

10.  “Novel, simple and efficient procedure for immobilization of proteins on glass-type surfaces” Feldman Fund Graduate Travel Award for 230th ACS national meeting, Washington DC, August 31, 2005.

Patents

1.      Tsai, S., Wexler, J. S., Wan, J., Stone, H. A. (2011) Microparticle conformal coating technology an a chip. US Patent. in application

2.      Forsyth, A., Wan, J., Kim, S., Tariq, A., Boehlert, J., Tsai, S., Persaud, N., Stone, H. A. (2011) Lab safety and information technology. US Patent. in application

3.      Wan, J., Stone, H. A. (2011). Microbubble-Templated Synthesis of Hollow Inorganic Particles.  US Patent. in application.

4.      Prud'homme, R., Sinko, P. J., Stone, H. A., Pinkerton, N. M.., Shi, L., Wan, J., Ibrahim, S. and Gao, D. (2010) Lung Targeting Dual Drug Delivery System. US Patent. in application.

5.      Stone, H. A., Wan, J. and Sullivan, M. (2008). Formation of particles for ultrasound applications, drug release, and other uses, and microfluidic methods of preparation. US Patent, in application.

6.      Stone, H. A., Ristenpart, W. D. and Wan, J. (2008). Reaction within microfluidic channels. US Patent. In application.

7.      Feng, Y., Da, S.,  Hu, Y. and Wan, J. (2002). Phenol-modified inorganic oxide composite as stationary phase of liquid Chromatography: its preparation and application Faming Zhuanli Shenqing Gongkai Shuomingshu   Patent  written in Chinese. Application: CN 2002-115835 20020514.

In the News

1.      Clay-armored bubbles may have formed first protocells. Harvard SEAS news: http://www.seas.harvard.edu/news-events/press-releases/clay-armored-bubbles. Harvard University Gazette news: http://news.harvard.edu/gazette/story/2011/02/clues-in-clay/?sms_ss=email&at_xt=4d5a9a86207f9172%2C0. MIT Technology Review, Harvard Gazette, Harvard Crimson, Pour la Science (French Scientific American), Physorg.com.

2.      Controllable microfluidic production of microbubbles in water-in-oil emulsions and the formation of porous microparticles. Harvard Magazine: The Harvard Center for Gastrophysics. March - April 2009,13-14.

3.       Study Shines Light on How Red Blood Cells Control Blood Pressure. UC Davis news and information: http://www.news.ucdavis.edu/search/news_detail.lasso?id=8836

4.      Print-and-Peel Method Creates Microfluidic Devices. Nanotech News from National Cancer Institute: http://nano.cancer.gov/news_center/nanotech_news_2006-12-04d.asp

5.      Developing Biofunctional Glass Coatings. BMES Bulletin, Biomedical Engineering Society Newspaper: 2007, 31, 16-17.