Refereed Journal articles

             *corresponding author

1. S. Kimura, J. Fukuda, A. Tajima, and H. Suzuki, On-chip diagnosis of subclinical mastitis in cows by electrochemical measurement of neutrophil activity in milk, Lab on a Chip, 12 (7), pp.1309-15 (2012) pdf

2. N. Mochizuki, T. Kakegawa, T. Osaki, N. Sadr, NN. Kachouie, H. Suzuki, J. Fukuda*, Tissue Engineering Based on Electrochemical Desorption of an RGD-Containing Oligopeptide, Journal of Tissue Engineering and Regenerative Medicine, in press pdf

3. N. Sadr, M. Zhu, T. Osaki, T. Kakegawa, Y. Yang, M. Moretti, J. Fukuda*, A. Khademhosseini*, SAM-based Cell Transfer to Photopatterned Hydrogels for Microengineering Vascular-Like Structures, Biomaterials, 32(30), pp. 7479-90 (2011) pdf

4. J. Fukuda*, Y. Kameoka, H. Suzuki, Spatio-temporal Detachment of Single Cells Using Microarrayed Transparent Electrodes, Biomaterials, 32(28), pp. 6663-9 (2011) pdf

5. K. Toda, Y. Yawata, E. Setoyama, J. Fukuda, N. Nomura, and H. Suzuki, Continuous monitoring of ammonia removal activity and observation of morphology of microbial complexes in a microdevice, Applied and Environmental Microbiology, 77(12), pp. 4253-5 (2011) pdf

6. C.H. Kwon, I. Wheeldon, N.N. Kachouie, S.H. Lee, H. Bae, S. Sant, J. Fukuda, J.W. Kang, and A. Khademhosseini, Drug-eluting microarrays for cell-based screening of chemical-induced apoptosis, Analytical Chemistry, 83 (11), pp 4118–25 (2011) (ACS, C&EN news) pdf

7. K. Okada, J. Fukuda, H. Suzuki, Rapid Diagnostic Device for Subclinical Mastitis Based on Electrochemical Detection of Superoxide Produced from Neutrophils in Fresh Milk, IEEJ Transactions on Sensors and Micromachines, 131 (6), pp. 218-222 (2011) pdf

8. J. Fukuda*, and K. Nakazawa, Hepatocyte spheroid arrays inside microwells connected with microchannels, Biomicrofluidics, 5, 022205 (2011) pdf

9. S. Numthuam, T. Kakegawa, T. Anada, A. Khademhosseini, H. Suzuki, J. Fukuda*, Synergistic effects of micro/nano modifications on electrodes for microfluidic electrochemical ELISA, Sensors and Actuators B, 156, 637-44 (2011) pdf

10. F. Yanagawa, H. Kaji, Y.H. Jang, H. Bae, D. Yanan, J. Fukuda, H. Qi, A. Khademhosseini, Directed assembly of cell-laden microgels for building porous three-dimensional tissue constructs, Journal of Biomedical Materials Research A, 97A (1), pp. 93-102 (2011) pdf

11. S. Numthuam, T. Ginoza, M. Zhu, H. Suzuki, J. Fukuda*, Gold-black micropillar electrodes for microfluidic ELISA of bone metabolic markers, Analyst, 136 (3), pp. 456-8 (2011) pdf

12. F. Sassa, H. Laghzali, J. Fukuda, H. Suzuki, Coulometric Detection of Components in Liquid Plugs by Microfabricated Flow Channel and Electrode Structures, Analytical chemistry, 82 (20), pp. 8725–32 (2010) pdf

13. N. Kachouie, Y. Du, H. Bae, M. Khabiry, A. F. Ahari, B. Zamanian, J. Fukuda, and A. Khademhosseini, Directed Assembly of Cell-Laden Hydrogels for Engineering Functional Tissues, Organogenesis, 6(4), pp. 234-44 (2010) pdf

14. T. Okuyama, H. Yamazoe, N. Mochizuki, A. Khademhosseini, H. Suzuki and J. Fukuda*, Preparation of arrays of cell spheroids and spheroid-monolayer cocultures within a microfluidic device, Journal of Bioscience and Bioengineering, 110, pp. 572-6 (2010) pdf

15. Y. Yawata, K. Toda, E. Setoyama, J. Fukuda, H. Suzuki, and N. Nomura, Monitoring Biofilm Development in Microfluidic-device by Modified Confocal Reflection Microscopy, Journal of Bioscience and Bioengineering, 110, pp. 377-80 (2010) pdf

16. T. Okuyama, H. Yamazoe, Y. Seto, H. Suzuki and J. Fukuda*, Cell Micropatterning inside a Microchannel and Assays under a Stable Concentration Gradient, Journal of Bioscience and Bioengineering, 110(2), pp. 230–7 (2010) pdf

17. T. Anada, T. Masuda, Y. Honda, J. Fukuda, F. Arai, T. Fukuda, and O. Suzuki, Three-dimensional cell culture device utilizing thin membrane deformation by decompression, Sensors and Actuators B, 147, pp. 376-9 (2010) pdf

18. Y. Yawata, K. Toda, E. Setoyama, J. Fukuda, H. Suzuki, H. Uchiyama and N. Nomura, Bacterial Growth Monitoring in a Microfludic Device by Confocal Reflection Microscopy, Journal of Bioscience and Bioengineering, 110, pp. 130-3 (2010) pdf

19. Y. Seto, R. Inaba, T. Okuyama, F. Sassa, H. Suzuki, J. Fukuda*, Engineering of Capillary-Like Structures in Tissue Constructs by Electrochemical Detachment of Cells, Biomaterials, 31, pp. 2209-15 (2010) pdf

20. N. Ohnishi, W. Satoh, K. Morimoto, J. Fukuda, H. Suzuki, Automatic electrochemical sequential processing in a microsystem for urea detection, Sensors and Actuators B, 144, pp. 146-52 (2010) pdf

21. Y. Sakai, T. Tanaka, J. Fukuda, and K. Nakazawa, Alkoxyresorufin O-dealkylase assay using a rat hepatocyte spheroid microarray, Journal of Bioscience and Bioengineering, 109(4), pp. 395-399 (2010) pdf

22. H. Yamazoe, T. Okuyama, H. Suzuki, J. Fukuda*, Fabrication of Patterned Cell Co-Cultures on Albumin-Based Substrate, Acta Biomaterialia, 6, pp. 526-33 (2010) pdf

23. P. Siribunbandal, S. Yamaguchi, K. Kojima, J. Fukuda, and H. Suzuki, Autonomous microfluidic transport using electrowetting-based valves and integrated cells, Applied Physics Letters, 95, 204105 (2009) pdf

24. S. Takahashi, H. Yamazoe, F. Sassa, H. Suzuki, J. Fukuda*, Preparation of Coculture System with Three Extracellular Matrices Using Capillary Force Lithography and Layer-by-layer Deposition, Journal of Bioscience and Bioengineering, 108(6), pp. 544-50 (2009) pdf

25. R. Inaba, A. Khademhosseini, H. Suzuki, J. Fukuda*, Electrochemical Desorption of Self-Assembled Monolayers for Engineering Cellular Tissues, Biomaterials, 30(21), pp. 3573-9 (2009) pdf

26. S. Yamaguchi, K. Morimoto, J. Fukuda, and H. Suzuki, Electrowetting-based pH- and biomolecule-responsive valves and pH filters, Biosensors and Bioelectronics, 24(7), pp. 2171-6 (2009) pdf

27. W. Satoh, S. Takahashi, F. Sassa, J. Fukuda, and H. Suzuki, On-chip Culturing of Hepatocytes and Monitoring their Ammonia Metabolism, Lab on a Chip, 9(1), pp. 35-7 (2009) pdf

28. S. Numthuam, H. Suzuki, J. Fukuda, S. Phunsiri, S. Rungchang, T. Satake, Rapid measurement and prediction of bacterial contamination in milk using an oxygen electrode, Foodborne Pathogens and Disease, 6(2), pp. 187-92 (2009)

29. Y. Shimizu, A. Takashima, W. Satoh, F. Sassa, J. Fukuda, H. Suzuki, Biochip with Integrated Pumps for Plug-Based Sequential Exchange of Solutions, Sensors and Actuators B, 140(2), pp. 649-55 (2009) pdf

30. K. Morimoto, S. Yamaguchi, J. Fukuda, and H. Suzuki, Towards Microsystems for Automatic Acquisition of in vivo Gastrointestinal Information, Journal of Applied Physics, 105(10), 102013 (2009) pdf

31. H. Yokomaku, W. Satoh, J. Fukuda, H. Suzuki, Electrowetting on Gold Electrodes with Microscopic Three-Dimensional Structures for Microfluidic Devices, Journal of Applied Physics, 104(6), pp. 064910-8 (2008) pdf

32. F. Sassa, J. Fukuda, H. Suzuki, Microprocessing of Liquid Plugs for Bio / chemical Analyses, Analytical Chemistry, 80 (16), pp.6206-13(2008) pdf

33. H. Hosono, W. Satoh, M. Toya, K. Morimoto, J. Fukuda, H. Suzuki, Microanalysis system with automatic valve operation, pH regulation, and detection functions, Sensors and Actuators B, 132(2), pp. 614-22 (2008) pdf

34. K. Morimoto, M. Toya, J. Fukuda, and H. Suzuki, Automatic Electrochemical Micro-pH-Stat for Biomicrosystems, Analytical Chemistry, 80(4), pp. 905-14 (2008) pdf

35. J. Karp, J. Yeh, G. Eng, J. Fukuda, J. Blumling, K.Y. Suh, J. Cheng, A. Mahdavi, J. Borenstein, R. Langer and A. Khademhosseini, Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells, Lab on a Chip, 7, pp. 786–794 (2007) pdf

36. H. Hosono, W. Satoh, J. Fukuda, and H. Suzuki, Micro Analysis System Based on Electrochemiluminescence Detection, Sensors and Materials, 19(4), pp. 191-201 (2007)

37. M. Hashimoto, N. Sakamoto, S. Upadhyay, J. Fukuda, and H. Suzuki, Enzyme Electrode Formed by Evaporative Concentration and its Performance Characterization, Biosensors and Bioelectronics, 22(12), pp. 3154-60 (2007) pdf

38. N. Nashida, W. Satoh, J. Fukuda, and H. Suzuki, Electrochemical immunoassay on a microfluidic device with sequential injection and flushing functions, Biosensors and Bioelectronics, 22(12), pp. 3167-73 (2007) pdf

39. K. Morimoto, S. Upadhyay, T. Higashiyama, N. Ohgami, H. Kusakabe, J. Fukuda, H. Suzuki, Electrochemical microsystem with porous matrix packed beds for enzyme analysis, Sensors and Actuators B, 124(2), pp. 477-485 (2007) pdf

40. H. Hosono, W. Satoh, J. Fukuda, H. Suzuki, On-chip handling of solutions and electrochemiluminescence detection of amino acids, Sensors and Actuators B, 122(2), pp.542-548 (2007) pdf

41. M. Shimada, Y. Yamashita, S. Tanaka, K. Shirabe, K. Nakazawa, H. Ijima, R. Sakiyama, J. Fukuda, K. Funatsu, K. Sugimachi, Characteristic gene expression induced by polyurethane foam/spheroid culture of hepatoma cell line, Hep G2 as a promising cell source for bioartificial liver, Hepato-gastroenterology; 54(75), pp. 814-20 (2007)

42. A. Khademhosseini, G. Eng, J. Yeh, J. Fukuda, J. 3rd Blumling, R. Langer, JA. Burdick, Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment, Journal of Biomedical Materials Research A, 79(3), pp. 522-32 (2006) pdf

43. A. Khademhosseini, L. Ferreira, J. Blumling III, J. Yeh, J. Karp, J. Fukuda, R. Langer, Co-culture of Human Embryonic Stem Cells with Murine Embryonic Fibroblasts on Microwell Patterned Substrates, Biomaterials, 27(36), pp.5968-77 (2006) pdf

44. J. Fukuda, A. Khademhosseini, Y. Yeo, X. Yang, J. Yeh, G. Eng, J. Blumling, CF Wang, D. Kohane, R. Langer, Micromolding of photocrosslinkable chitosan hydrogel for spheroid microarray and co-cultures, Biomaterials, 27(30), pp.5259-67 (2006) pdf

45. K. Nakazawa, Y. Izumi, J. Fukuda and T. Yasuda, Hepatocyte spheroid culture on a polydimethylsiloxane chip having microcavities, Journal of Biomaterials Science-polymer edition, 17(8), pp.859-73 (2006) pdf

46. Khademhosseini, C. Bettinger, J. Karp, J. Yeh, Y. Ling, J. Borenstein, J. Fukuda, R. Langer, Interplay of biomaterials and micro-scale technologies for advancing biomedical applications, Journal of Biomaterials Science: Polymer Edition, 17(11), pp.1221-40 (2006) pdf

47. J. Fukuda, A. Khademhosseini, J. Yeh, G. Eng, J. Cheng, O. Farokhzad, R. Langer, Micropatterned cell co-cultures using layer-by-layer deposition of extracellular matrix components, Biomaterials, 27(8), pp.1479-86 (2006) pdf

48. K. Nakazawa, S-W. Lee, J. Fukuda, D-H. Yang, T. Kunitake, Hepatocyte spheroid formation on a titanium dioxide gel surface and hepatocyte long-term culture, Journal of Materials Science: Materials in Medicine, 17(4), pp359-64 (2006) pdf

49. R. Karinaga, T. Anada, M. Mizu, K. Koumoto, J. Fukuda, K. Nakazawa, T. Hasegawa, M. Mumata, S. Shinkai, K. Sakurai, Galactose-PEG dual conjugation of b-(1→3)-D-glucan schizophyllan for antisense oligonucleotides delivery to enhance the cellular uptake, Biomaterials, 27(8), pp.1626-35 (2006) pdf

50. J. Fukuda, Y. Sakai, K. Nakazawa, Novel hepatocyte culture system by using micro-fabrication and collagen/PEG micro-contact printing, Biomaterials, 27(7), pp.1061-70 (2006) pdf

51. J. Fukuda, K. Okamura, K. Ishihara, H. Mizumoto, K. Nakazawa, H. Ijima, T. Kajiwara, K. Funatsu, Differentiation effects by the combination of spheroid formation and sodium butyrate treatment in human hepatoblastoma cell line (Hep G2): a possible cell source for hybrid artificial liver, Cell Transplantation, 14(10), pp.819-27 (2005) pdf

52. J. Fukuda, K. Nakazawa, Orderly arrangement of hepatocyte spheroids on a microfabricated chip, Tissue Engineering, 11(7-8), pp.1254-62 (2005) pdf

53. Y. Yamashita, M. Shimada, N. Harimoto, S. Tanaka, K. Shirabe, H. Ijima, K. Nakazawa, J. Fukuda, K. Funatsu, Y. Maehara, cDNA microarray analysis in hepatocyte differentiation in Huh 7 cells, Cell Transplantation, 13, pp.793-9 (2004) pdf

54. J. Fukuda, H. Mizumoto, K. Nakazawa, T. Kajiwara, K. Funatsu, Hepatocyte organoid culture in elliptic hollow fibers to develop a hybrid artificial liver, The International Journal of Artificial Organs, 27, pp.1091-9 (2004) pdf

55. Y. Yamashita, M. Shimada, E. Tsujita, K. Shirabe, H. Ijima, K. Nakazawa, R. Sakiyama, J. Fukuda, K. Funatsu, K Sugimachi, Efficacy of a larger version of the hybrid artificial liver support system using a polyurethane foam/spheroid packed-bed module in a warm ischemic liver failure pig model for preclinical experiments, Cell Transplantation, 12, pp.101-7 (2003) pdf

56. J. Fukuda, K. Okamura, K. Nakazawa, H. Ijima, Y. Yamashita, M. Shimada, K. Shirabe, E. Tsujita, K. Sugimachi, K. Funatsu, Efficacy of a polyurethane foam / spheroid artificial liver by using human hepatoblastoma cell line (Hep G2), Cell Transplantation, 12, pp.51-58 (2003) pdf

57. Y. Yamashita, M. Shimada, E. Tsujita, K. Shirabe, H. Ijima, K. Nakazawa, R. Sakiyama, J. Fukuda, K. Funatsu, K. Sugimachi, High metabolic function of primary human and porcine hepatocytes in a polyurethane foam / spheroid culture system in plasma from patients with fulminant hepatic failure, Cell Transplantation, 11, pp.379-84 (2002) pdf

58. K. Nakazawa, H. Ijima, J. Fukuda, R. Sakiyama, Y. Yamashita, M. Shimada, K. Shirabe, E. Tsujita, K. Sugimachi, K. Funatsu, Development of a hybrid artificial liver using polyurethane foam / hepatocyte spheroid culture in a preclinical pig experiment, The International Journal of Artificial Organs, 25, pp.51-60 (2002) pdf

59. J. Fukuda, R. Sakiyama, K. Nakazawa, H. Ijima, Y. Yamashita, M. Shimada, K. Shirabe, E. Tsujita, K. Sugimachi, K. Funatsu, Mass preparation of primary porcine hepatocytes and the design of a hybrid artificial liver module using spheroid culture for a clinical trial, The International Journal of Artificial Organs, 24, pp.799-806 (2001) pdf

60. Y. Yamashita, M. Shimada, E. Tsujita, S. Tanaka, H. Ijima, K. Nakazawa, R. Sakiyama, J. Fukuda, T. Ueda, K. Funatsu, K. Sugimachi, Polyurethane foam / spheroid culture system using human hepatoblastoma cell line (Hep G2) as a possible new hybrid artificial liver, Cell Transplantation, 10, pp.717-22 (2001) pdf

61. Y. Yamashita, M. Shimada, E. Tsujita, T. Rikimaru, H. Ijima, K. Nakazawa, R. Sakiyama, J. Fukuda, K. Funatsu, K. Sugimachi, The efficacy of nafamostat mesilate on the performance of a hybrid artificial liver using a polyurethane foam/porcine hepatocyte spheroid culture system in human plasma, The International Journal of Artificial Organs, 24, pp.34-40 (2001) pdf

62. H. Ijima, K. Nakazawa, M. Kaneko, J. Fukuda, M. Shimada, Y. Yamashita, T. Gion, M. Shirabe, K. Sugimachi, K. Funatsu, Development of a hybrid artificial liver support system and preclinical animal experiments, Journal of Artificial Organs, 3, pp.112-6 (2000) pdf

63. M. Kaneko, J. Fukuda, H. Ijima, K. Nakazawa, T. Gion, M. Shimada, K. Shirabe, K. Takenaka, K. Sugimachi, K. Funatsu, Development of hybrid artificial liver support system using spheroid culture and application to warm ischemic liver failure in dog and pig as a preclinical test, Materials Science and Engineering C6, pp.245-8 (1998) pdf