The goal of our lab is to develop noninvasive functional and diffusion MRI methods and imaging markers for early detection of neural plasticity in activity and connectivity to neurocytoarchitecture, and for evaluation of treatment in neurodegenerative diseases.

(I) We used activity-induced Manganese-dependent contrast to map rat barrel activation following whisker stimulation, and used BOLD functional MRI to map plasticity in the forepaw digit barrel subfield of rat brains.

(II) We evaluated the rabbit brain development and brain injury after cerebral hemisphere radiation exposure using generalized q-sampling imaging (GQI).

(III) We also evaluated the rat and rabbit brain changes after infection of Angiostrongylus Cantonensis using advanced diffusion methods.

(IV) We used manganese-enhanced MRI (MEMRI) to prove Ceftriaxone prevents the neurodegeneration and decreased neurogenesis in a Parkinson’s disease rat model. We also used resting-state fMRI to investigate the effects of taurine in spontaneously hypertensive rats.

(V) We used GQI and graph theoretical analysis to reveal the gender differences in the structural connectome of the teenage brain, and to evaluate the structural connectivity changes in betel-quid chewers.

(VI) We also established neuroimaging markers in major depression disorder with self-harm or with suicidal ideation, patient with obesity, breast cancer patient, and children with reading difficulties in Chinese.

Recent Announcements

  • 2018/7 恭賀本實驗室一篇國際期刊論文獲得Brain Imaging and Behavior接受
    Posted Jul 16, 2018, 7:26 AM by JC Weng
  • 2018/7 恭賀翁老師獲得107年度科技部研究計畫
    Posted Jul 16, 2018, 7:26 AM by JC Weng
  • 2018/5 恭賀本實驗室一篇國際期刊論文獲得PeerJ接受
    Posted May 30, 2018, 6:23 AM by JC Weng
  • 2018/3 恭賀本實驗室一篇國際期刊論文獲得 Neuropsychiatry (London)接受
    Posted Mar 20, 2018, 4:10 AM by JC Weng
  • 2018/3 恭賀本實驗室一篇國際期刊論文獲得Behavioural Neurology接受
    Posted Mar 14, 2018, 3:33 AM by JC Weng
  • 2018/2 恭賀本實驗室五篇國際研討會論文獲得26th ISMRM Annual Meeting, Paris, France接受
    Posted Feb 2, 2018, 3:54 PM by JC Weng
  • 2018/1 恭賀本實驗室一篇國際期刊論文獲得Psychopharmacology接受
    Posted Jan 17, 2018, 8:13 PM by JC Weng
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