The goal of AIMRI lab is to develop noninvasive functional and diffusion MRI methods and imaging markers for early detection of neural plasticity in activity and connectivity to neurocytoarchitecture, and for evaluation of treatment in neurodegenerative diseases. We also use machine learning and deep learning to predict disease status with multiple MRI features. 

(I) We used activity-induced Manganese-dependent contrast to map rat barrel activation following whisker stimulation, and used BOLD functional MRI (fMRI) to map plasticity in the forepaw digit barrel subfield of rat brains.

(II) We evaluated the rabbit brain development and brain injury after cerebral hemisphere radiation exposure using generalized q-sampling imaging (GQI).

(III) We also evaluated the rat and rabbit brain changes after infection of Angiostrongylus Cantonensis using advanced diffusion methods.

(IV) We used manganese-enhanced MRI (MEMRI) to prove Ceftriaxone prevents the neurodegeneration and decreased neurogenesis in a Parkinson’s disease rat model. We also used resting-state fMRI to investigate the effects of taurine in spontaneously hypertensive rats.

(V) we used GQI, resting-state fMRI and graph theoretical analysis to reveal the gender differences in the structural connectome of the teenage brain, and to evaluate the structural and functional connectivity changes in betel-quid chewers.

(VI) We established neuroimaging markers in major depression disorder with suicide attempt or with suicide ideation, breast cancer patient, patient with obesity, and Chinese-speaking children with specific learning disabilities. 

(VII) We also used multiple MRI features and machine-learning to predict chemo-brain in breast cancer survivors.

Recent Announcements

  • 2019/11 恭賀本實驗室一篇國際期刊論文獲得Journal of Clinical Medicine接受
    Posted Nov 13, 2019, 8:04 AM by JC Weng
  • 2019/6 恭賀本實驗室四篇國際研討會論文獲得Society for Neuroscience, Chicago, IL, USA, 2019接受
    Posted Jun 21, 2019, 2:32 AM by JC Weng
  • 2019/6 恭賀莊維、宜芳獲得108學年度科技部補助大專學生研究計畫 
    Posted Jun 18, 2019, 12:40 AM by JC Weng
  • 2019/3 恭賀本實驗室五篇國際研討會論文獲得 25th Annual Meeting of the Organization for Human Brain Mapping, Rome, Italy接受
    Posted Mar 2, 2019, 7:22 PM by JC Weng
  • 2019/2 恭賀本實驗室國際研討會論文獲得27th ISMRM Annual Meeting, Montreal, QC, Canada接受
    Posted Mar 2, 2019, 7:21 PM by JC Weng
  • 2018/11 恭賀本實驗室一篇國際期刊論文獲得BMC Cancer接受
    Posted Nov 20, 2018, 5:25 AM by JC Weng
  • 2018/10 恭賀本實驗室一篇國際期刊論文獲得Magnetic Resonance in Medicine接受
    Posted Oct 23, 2018, 5:57 AM by JC Weng
  • 2018/10 恭賀本實驗室一篇國際期刊論文獲得Scientific Reports接受
    Posted Oct 23, 2018, 5:55 AM by JC Weng
  • 2018/10 恭賀本實驗室一篇國際期刊論文獲得Neuropsychiatric Disease and Treatment接受
    Posted Oct 23, 2018, 5:55 AM by JC Weng
  • 2018/9 恭賀薈茗獲得第十三屆國際醫學影像暨放射科學研討會醫學影像應用組海報第一名
    Posted Sep 30, 2018, 11:50 PM by JC Weng
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