The Journal for Urology

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The Journal for Urology, ISJN: 8429-5346, Impact Index: 4.38, Imprint: Photon, Category: Peer Reviewed Indexed International Journal


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Prevalence of Clinico-histologically diagnosed Prostatic Diseases: Experience from a budding Tertiary Centre 


Adegun Patrick Temia, Omonisi Abidemi Emmanuelb*, Atiba Adeniran Samuelc, Areo Peter Olufemia, Ajayi Oladimeji Akanded, Taiwo Olufemi Joshuab, Esho Julius Olusanmia, Odesanmi William Olufemib  


a Department of Surgery, College of Medicine, Ekiti State University, Ado-Ekiti, Ekiti State, Nigeria  

b Department of Anatomic Pathology, College of Medicine, Ekiti State University, Ado-Ekiti, Ekiti State, 

   Nigeria 

c Department of Chemical Pathology, College of Medicine, Ekiti State University, Ado-Ekiti, Ekiti State, 

   Nigeria 

d Department of Medicine, College of Medicine, Ekiti State University, Ado-Ekiti, Ekiti State, Nigeria    


Adegun Patrick Temi, Omonisi Abidemi Emmanuel, Atiba Adeniran Samuel, Areo Peter Olufemi, Ajayi Oladimeji Akande, Taiwo Olufemi Joshua, Esho Julius Olusanmi and Odesanmi William Olufemi are conferred with Max Planck Research Award-2015 in Urology 


Photon Ignitor: ISJN84295346D738907042015 


Citation: Temi A.P., Emmanuel O.A., Samuel A.A., Olufemi A.P., Akande A.O., Joshua T.O., Olusanmi E.J., Olufemi O.W., 2015. Prevalence of Clinico-histologically diagnosed Prostatic Diseases: Experience from a budding Tertiary Centre. The Journal for Urology. Photon 112, 130-138. 


Abstract 

Introduction: Prostatic diseases have emerged as significant health challenges in most elderly man aged 50 and above. There is no existing literature on the prevalence of prostatic diseases in this environment. Recently, there has been renewed interest in understanding the wide range of diseases affecting the prostate glands. This retrospective study was to describe the prevalence, clinical features, histology and pathological characteristics of prostatic diseases in Ado-Ekiti, Nigeria. Materials and Methods: The results of all prostatic tissue specimens received in the Anatomic Pathology at Ekiti State University Teaching Hospital, Ado-Ekiti from January 2008 to December 2013 were analyzed in addition to the patients’ clinical details. A total of 141 specimens were studied. Gleason’s microscopic and the TNM classifications were used to grade all the malignant lesions.PSA was correlated with the malignant cases. Results: The minimum age of diagnosis was 45 years while the maximum age at diagnosis was 95 years. The mean age for BPH was 72.6 years; mean age for adenocarcinoma was 74.4 years. History of poor urinary stream in was the commonest symptoms. There were strong associations between adenocarcinoma of the prostate with weight loss and back pain [p<0.05]. Significant numbers of the prostatic adenocarcinoma showed abysmal elevation in the levels of PSA with a mean value of 66.2 ng/ml. Conclusions: This study has shown that prostatic diseases have emerged as a major health problem in Nigerian young adult males aged 45 and above and no longer the disease of the elderly only. The level of serum PSA for subjecting patient to prostatic biopsy must be decided alongside the clinical details and not just based on the recommended cut-off points in the literature because of the abysmally high levels recorded for BPH in this environment.



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