Wine Linked to Bone Repair

Wine Linked to Bone Repair “New Study” Sounds Promising


“Coffee is good for me, bad for me, good for me, bad for me”, we have all read the studies going back and forth over the years from the many experts and scientists in their fields. Well, now here comes another one, this one in the wine industry and linking moderate consumption of wine to bone repair.  Here is a copy of the article and a copy of the actual clinical test for your reading perusal. You decide …


A Glass of Wine a Day Keeps Osteoporosis Away For Women: Study


Carmen Chai, Global News : Thursday, July 12, 2012 4:29 PM


TORONTO – Mothers used to coax their kids into drinking a glass of milk to strengthen their bones, and now scientists are suggesting that women indulge in a glass of wine to stave off osteoporosis.

Push aside any feelings of guilt when you indulge in a glass or wine or a pint of beer – American researchers say their research suggests “moderate” amounts of alcohol is linked to decreased bone loss, lowering the risk of developing osteoporosis.  Scientists at Oregon State University say women who sip on one or two libations a day a few times a week had stronger bones compared to when they stopped alcohol intake for two weeks.

The research also showed that just a day after resuming a daily drink, women’s “bone turnover” rates – a measure of density – returned to normal, healthy levels. “Drinking moderately as part of a healthy lifestyle that includes a good diet and exercise may be beneficial for bone health, especially in postmenopausal women,” lead author Urszula Iwaniec said in a statement.

Iwaniec’s complete study was published in Menopause Thursday.
Osteoporosis is a condition that causes bones to become thin and porous, decreasing bone density, leading to an increased risk of breaking a limb.

Women and men alike begin to lose bone density in their mid 30s, and as they approach menopause, women lose bone mass at a greater rate, from two to three per cent per year, according to Osteoporosis Canada. In the study, 40 early post-menopausal women were followed. They had a habit of drinking one or two drinks a day, they weren’t undergoing hormone replacement therapies and they had no history of osteoporosis-related fractures.

While the researchers’ results may be good news for women, they concede that the study sample is small and that further investigation is necessary.
They hope to discover how alcohol is linked to protecting women’s bones. Another study published this week by Swedish scientists found that three glasses of wine a week halves the risk of certain forms of arthritis a women.  While readers may celebrate these findings, both studies note that drinking in moderation is an integral factor.  Canadian guidelines suggest that women should have no more than 10 drinks a week, with no more than two drinks on most days.


© Global News. A division of Shaw Media Inc., 2012.



Moderate Alcohol Intake Lowers Biochemical Markers of Bone Turnover in Postmenopausal Women


Marrone, Jill A. MS; Maddalozzo, Gianni F. PhD; Branscum, Adam J. PhD; Hardin, Karin MS; Cialdella-Kam, Lynn PhD; Philbrick, Kenneth A. MS; Breggia, Anne C. PhD; Rosen, Clifford J. MD; Turner, Russell T. PhD; Iwaniec, Urszula T. PhD




Objective: Epidemiological studies indicate that higher bone mass is associated with moderate alcohol consumption in postmenopausal women. However, the underlying cellular mechanisms responsible for the putative beneficial effects of alcohol on bone are unknown. Excessive bone turnover, combined with an imbalance whereby bone resorption exceeds bone formation, is the principal cause of postmenopausal bone loss. This study investigated the hypothesis that moderate alcohol intake attenuates bone turnover after menopause.


Methods: Bone mineral density was determined by dual-energy x-ray absorptiometry in 40 healthy postmenopausal women (mean +/- SE age, 56.3 +/- 0.5 y) who consumed alcohol at 19 +/- 1 g/day. Serum levels of the bone formation marker osteocalcin and the resorption marker C-terminal telopeptide (CTx) were measured by immunoassay at baseline (day 0) and after alcohol withdrawal for 14 days. Participants then consumed alcohol and were assayed on the following morning.


Results: Bone mineral density at the trochanter and total hip were positively correlated to the level of

alcohol consumption. Serum osteocalcin and CTx increased after abstinence (4.1 +/- 1.6%, P = 0.01 and 5.8 +/- 2.6%, P = 0.02 compared with baseline, respectively). Osteocalcin and CTx decreased after alcohol readministration, compared with the previous day (-3.4 +/- 1.4%, P = 0.01 and -3.5 +/- 2.1%, P = 0.05, respectively), to values that did not differ from baseline (P > 0.05).


Conclusions: Abstinence from alcohol results in increased markers of bone turnover, whereas resumption of alcohol reduces bone turnover markers. These results suggest a cellular mechanism for the increased bone density observed in postmenopausal moderate alcohol consumers. Specifically, the inhibitory effect of alcohol on bone turnover attenuates the detrimental skeletal consequences of excessive bone turnover associated with menopause.