Biomedical Photonics at Notre Dame

The biomedical photonics group focuses on how the interaction of photons and tissue can be used to aid diagnosis and fundamental research in biological fields. The group's work thus spans optoelectronic device development (e.g. QCLs) to be used as sources in systems, technique development (e.g. fast full frame FLIM), contrast agent development (e.g. encapsulation of nonlinear optical dyes), and new platform development (e.g. low-cost PCR thermal cyclers coupled with tunable laser spectroscopy for analysis and THz imaging/spectroscopy systems.) The work is highly interdisciplinary. 

Located in the new Stinson-Remick Hall

Current Projects:

3D Chemical Sensing in-vivo

By combining multiphoton microscopy (MPM) and fluorescence lifetime microscopy (FLIM), we are developing new technology for imaging phosphorecence quenching dyes. This technology enables researchers to measure the concentration of chemical species inside living animals with sub-micron resolution.

Mid-IR and THz

Long wave infrared light is usefull for chemcally specefic imaging by measuring the amount of light absorbed by molecules at vibrational resonances. At Notre Dame, we're developing new Mid-IR and THz sources (such as quantum cascade lasers), detectors, and applications. Design and modeling, growth, characterization, and integration work is on going.

BioTech for the Developing World

Advances in technology have simultaneous given us new capabilities and reduce the cost of our capabilities. Current projects look at new methods of providing high quality medical devices at low cost. Examples include solar-powered PCR systems for microfuidic and laser absorption spectroscopy of DNA and low-cost endoscopes.