Publications

        72. Seong Mi Choi, Kyoung-Mi Lee, Hyun Jung Kim, Ik Kyu Park, Hwi Ju Kang, Hang-Cheol Shin, Dawoon Baek, Yoorim Choi, Kwang Hwan Park, Jin Woo Lee (2018)
        "Effects of structurally stabilized EGF and bFGF on wound healing in type I and type II diabetic mice" Acta Biomaterialia, 66, 325-334 

        71. Byung In Ro, Suk Young Lee, Jong Baik Kim, and Hang Cheol Shin (2017) “Therapeutic effects of growth factor cocktail including fibroblast growth factor 9 in patients
        with pattern hair loss” Korean Journal of Dermatology, 55(8), 504-510

        70. Seungryong Heo, Juyong Lee, Keehyoung Joo, Hang-Cheol Shin and Jooyoung Lee (2017) “Protein loop structure prediction using conformational space annealing” 
        Journal of Chemical Information and Modeling 57 (5), 1068–1078

        69. Byung In Ro, Sin Wook Chun, Suk Young Lee and Hang Cheol Shin (2016) "Therapeutic effects of growth factor cocktail including fibroblast growth factor-9 in
        patients with androgenetic alopecia - a split study" Global Dermatology, 3(6), 404-408


68. Seong Mi Choi,  Hyun Aae Ryu, Kyoung-Mi Lee, Hyun Jung Kim, Ik Kyu Park, Wan Jin Jo, Hang-Cheol Shin, Woo Jin Choi and Jin Woo Lee (2016) "Development of stabilized growth factor-loaded hyaluronate-collagen dressing (HCD) matrix for impaired wound healing" Biomaterials Research 20:9, 1-7


67. Byung In Ro, Hyun Ok Son, Sin Wook Chun and Hang-Cheol Shin (2016) "Therapeutic effects of growth factor cocktail treatment in patients with androgenetic alopecia according to the depth of microneedle" Korean Journal of Dermatology, 54(3), 184-189


66. Dongho Shin, Keehyoung Joo, Jooyoung Lee and Hang-Cheol Shin (2015) “Single-chain insulin analogs as an insulin agonist and their implications for receptor binding” Biodesign, 3(4), 168-174


65. Kwang-Su Ock, Uuriintuya Dembereldorj, Jin Park, Erdene-Ochir Ganbold, Semi Kim, Hang-Cheol Shin, Sang-Woo Joo (2013) “Temperature-dependent structural change of D-penicillamine-capped chiral gold nanoparticles investigated by infrared spectroscopy” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 102, 419-424

 

64.  Haarin Chun, Keehyoung Joo, Jooyoung Lee & Hang-Cheol Shin (2011) “Design and efficient production of bovine enterokinase light chain with higher specificityBiotechnology Letters 33, 1227-1232

 

63.  Hyosun Oh, Sunggeon Ko, Sunjin Moon, Hang-Cheol Shin & Weontae Lee (2009) “Purification and NMR studies on phosphatase domain of UBLCP1” Journal of the Korean Magnetic Resonance Society 13, 126-134

 

62.  Seung-Hwan Jang, Hyang-Do Song, Dong-Ku Kang, Soo-Ik Chang, Min Kyung Kim, Kwang-Hwi Cho, Harold A. Scheraga & Hang-Cheol Shin (2009) “Role of the surface loop on the structure and biological activity of angiogenin” BMB Reports 42, 829-833

 

61.  Min Kyung Kim, Young-Joo Seol, Hyun Seok Park, Seung-Hwan Jang, Hang-Cheol Shin & Kwang-Hwi Cho (2009) “A new approach to find orthologous proteins using sequence and protein-protein interaction similarity” Genomics and Informatics 7, 141-147

 

60.  Seung-Hwan Jang, Hyojin Kim, Kwang-Hwi Cho & Hang-Cheol Shin (2009) “Development of human tumor necrosis factor-a muteins with improved therapeutic potential” BMB Reports 42, 260-264

 

59.  Woonghee Kim, Sun-Hee Back, Dong-Il Kang, Hang-Cheol Shin & Yangmee Kim (2008) “NMR Assignment of des [40-93] Mutant of Bovine Angiogenin” Bulletin of the Korean Chemical Society, 29, 2259-2263

 

58.  Seong Il Choi, Kyoung Sim Han, Chul Woo Kim, Ki-Sun Ryu, Byung Hee Kim, Kyun-Hwan Kim, Seo-Il Kim, Tae Hyun Kang, Hang-Cheol Shin, Keo-Heun Lim, Hyo Kyung Kim, Jeong-Min Hyun & Baik L. Seong (2008) “Protein solubility and folding enhancement by interaction with RNA” PLoS ONE 3(7), e2677

 

57.  Ervin Welker, Laura Hathaway, Guoqiang Xu, Mahesh Narayan, Lovy Pradeep, Hang-Cheol Shin & Harold A. Scheraga (2007) “Oxidative folding and N-terminal cyclization of onconase” Biochemistry 46, 5485-5493

 

56.  Sun-Hee Baek, Dong-Il Kang, Jee-Young Lee, Hang-Cheol Shin & Yang-Mee Kim (2006) “Chmical Shift Variation of Bovine Angiogenin Upon Binding with Phosphate ions” Journal of the Korean Magnetic Resonance Society 10(2) 155-162.

 

55.  Lovy Pradeep, Hang-Cheol Shin & Harold A. Scheraga (2006) “Correlation of folding kinetics with the number and isomerization states of prolines in three homologous proteins of the RNase family” FEBS Letters, 580, 5029-5032

 

54.  Jin-Kyu Rhee, Do-Yun Kim, Dae-Gyun Ahn, Jung-Hyuk Yun, Seung-Hwan Jang, Hang-Cheol Shin, Hyun-Soo Cho, Jae-Gu Pan & Jong-Won Oh (2006) “Analysis of the thermostability determinants of hyperthermophilic esterase EstE1 based on its predicted three-dimensional structure” Applied and Environmental Microbiology, 72, 3021-3025

 

53.  Seung Do Hong, Hang-Cheol Shin & Kwang-Hwi Cho (2005) “Direct and highly efficient estimation of the entropy through the canonical ensemble average of acceptance ratios” Bulletin of the Korean Chemical Society, 26, 1673-1674

 

52.  Hang-Cheol Shin & Kwang-Hwi Cho (2005) “Mutational analysis of human tumor necrosis factor-alpha” Biotechnology Letters, 27, 107-112

 

51.  Won-Seok Choi, Weon-Kyoo You, You-Seok Koh, Hang-Cheol Shin, Young-Doug Sohn, Yangsoo Jang & Kwang-Hoe Chung (2004) “Activity and safety of recombinant batroxobin, a thrombin-like enzyme”, Korean Journal of Thrombosis and Hemostasis, 11(1), 19-27

 

50.  Seung-Hwan Jang, Dong-Ku Kang, Soo-Ik Chang, Harold A. Scheraga & Hang-Cheol Shin (2004) “High level production of bovine angiogenin in E. coli by an efficient refolding procedure” Biotechnology Letters, 26, 1501-1504

 

49.  Weon-Kyoo You, Won-Seok Choi, You-Seok Koh, Hang-Cheol Shin, Yangsoo Jang & Kwang-Hoe Chung (2004) “Functional characterization of recombinant batroxobin, a snake venom thrombin-like enzyme, expressed from Pichia pastoris” FEBS Letters, 571, 67-73

 

48.  Woojin Jeong & Hang-Cheol Shin (2004) “Formation of an alpha-helix in human tumor necrosis factor-alpha by guanidine hydrochloride-induced unfolding” Molecules and Cells, 17, 62-66

 

47.  Seung-Gu Chang, Ki-Doo Choi, Seung-Hwan Jang & Hang-Cheol Shin (2003) “Role of disulfide bonds in the structure and activity of human insulin” Molecules and Cells, 16, 323-330

 

46.  Hang-Cheol Shin, Mahesh Narayan, Myeong-Cheol Song & Harold A. Scheraga (2003) “Role of the [65-72] disulfide bond in oxidative folding of bovine pancreatic ribonuclease A”, Biochemistry, 42, 11514-11519

 

45.  Seung-Gu Chang, Ki-Doo Choi, Dae-Young Kim, Hee-Taik Kang, Myeong-Cheol Song & Hang-Cheol Shin (2002) “The role of β-turn in the folding of mini-proinsulins”, Bulletin of the Korean Chemical Society, 23, 1369-1370

 

44.  Hang-Cheol Shin, Myeong-Cheol Song & Harold A. Schearga (2002) “Effect of protein disulfide isomerase on the rate-determining steps of the folding of bovine pancreatic ribonuclease A”, FEBS Letters, 521, 77-80

 

43.  Lawrence K. Low, Hang-Cheol Shin & Harold, A. Scheraga (2002) “Oxidative folding of bovine pancreatic ribonuclease A: Insight into the overall catalysis of the refolding pathway by phosphate”, Journal of Protein Chemistry, 21, 19-27

 

42. Hang-Cheol Shin (2001) "Protein Folding" Korean Biophysical Society Newsletter, 7(1), 6-10

 

41.  Chul Soo Shin, Min Seon Hong, Hang-Cheol Shin & Jeewon Lee (2001) “High-level production of recombinant human IFN-α2a with co-expression of tRNAArg(AGG/AGA) in high-cell-density cultures of Escherichia coli”, Biotechnology and Bioprocess Engineering, 6, 301-305

 

40.  Hang-Cheol Shin (2001) “Protein folding, misfolding and refolding of therapeutic proteins”, Biotechnology and Bioprocess Engineering, 6, 237-243

 

39.  Hyun Chul Lee, Su-Jin Kim, Kyung-Sup Kim, Hang-Cheol Shin & Ji-Won Yoon (2000) “Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue”, Nature, 408, 483-488; [News & View] 420-421

 

38.  Hang-Cheol Shin & Harold A. Scheraga (2000) “Catalysis of the oxidative folding of bovine pancreatic ribonuclease A by protein disulfide isomerase”, Journal of Molecular Biology, 300, 995-1003

 

37.  Yoon-Sang Cho, Seung-Gu Chang, Ki-Doo Choi, Hang-Cheol Shin, Byung-Yoon Ahn & Key-Sun Kim (2000) “Solution structure of an active mini-proinsulin, M2PI: Inter-chain flexibility is crucial for insulin activity”, Journal of Biochemistry and Molecular Biology, 33, 120-125


36. Su-Jin Kim, Kyung-Sup Kim, Hang-Cheol Shin & Hyun-Chul Lee (2000) “Cure for diabetes: mutant proinsulin expression driven by L-pyruvate kinase (LPK) promoter normalizes blood glucose levels in streptozotocin-induced diabetic ratsDiabetes, 49(5), A53


35.  Lawrence K. Low, Hang-Cheol Shin, Mahesh Narayan, William J. Wedemeyer & Harold, A. Scheraga (2000) “Acceleration of oxidative folding of bovine pancreatic ribonuclease A by anion-induced stabilization and formation of structured native-like intermediates”, FEBS Letters, 472, 67-72

 

34.  Sun-Shin Cha, Min-Sung Kim, Yo Han Choi, Byung-Je Sung, Nam Kyu Shin, Hang-Cheol Shin, Young Chul Sung & Byung-Ha Oh (1999) “2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity”, Immunity, 11, 253-261

 

33.  Hang-Cheol Shin & Harold A. Scheraga (1999) “The effect of protein disulfide isomerase on the regeneration of bovine pancreatic ribonuclease with dithiothreitol”, FEBS Letters, 456, 143-145

 

32.  Sun-Shin Cha, Hang-Cheol Shin, Kwan Yong Choi & Byung-Ha Oh (1999) “Expression, purification, and crystallization of recombinant human TRAIL”, Acta Crystallographica, D55, 1101-1104

 

31.  Yeoun Jin Kim, Sun-Shin Cha, Jeong-Sun Kim, Nam-Kyu Shin, Woojin Jeong, Hang-Cheol Shin, Byung-Ha Oh & Jong Hoon Hahn (1999) “Determination of the limited trypsinolysis pathways of tumor necrosis factor-alpha and its mutant by electrospray ionization mass spectrometry”, Analytical Biochemistry, 267, 279-286

 

30. Yong-Rok Kim, Joong-Sik Hahn, Heedeok Hong, Woojin Jeong, Nam Woong Song, Hang-Cheol Shin & Dongho Kim (1999) “Dynamic equilibrium unfolding pathway of human tumor necrosis factor-α induced by guanidine hydrochloride”, Biochimica et Biophysica Acta, 1429, 486-495

 

29.  Woojin Jeong, Hang-Cheol Shin & Yong-Rok Kim (1998) “Resonance energy transfer in the equilibrated unfolding states of human tumor necrosis factor-α”, Bulletin of the Korean Chemical Society, 19, 608-611

 

28.  Nam-Kyu Shin, Dae-Young Kim, Cheol-Soo Shin, Min-Sun Hong, Jeewon Lee & Hang-Cheol Shin (1998) “High level production of recombinant human growth hormone in Escherichia coli by a simple recombinant process”, Journal of Biotechnology, 62, 143-151

 

27.  Nam-Kyu Shin, Inkyung Lee, Seung-Gu Chang & Hang-Cheol Shin (1998) "A novel tumor necrosis factor-alpha mutant with enhanced cytotoxicity and receptor binding affinity", Biochemistry and Molecular Biology International, 44, 1075-1082

 

26.  Cheol-Soo Shin, Min-Sun Hong, Jeewon Lee, Dae-Young Kim, Nam-Kyu Shin & Hang-Cheol Shin (1998) “Growth-associated synthesis of recombinant human glucagon and human growth hormone in high cell density cultures of Escherichia coli”, Applied Microbiology and Biotechnology, 49, 364-370

 

25.  Hang-Cheol Shin (1998) “Effect of lipids on the conformation of an antigenic determinant for experimental autoimmune neuritis”, Biochemistry and Molecular Biology International, 44, 771-776

 

24.  Woojin Jeong & Hang-Cheol Shin (1998) “Supply of argU gene product allows high-level expression of recombinant human interferon-α2a in Escherichia coli”, Biotechnology Letters, 20, 19-22

 

23.  Sun-Shin Cha, Jeong-Sun Kim, Hyun-Soo Cho, Nam-Kyu Shin, Woojin Jeong, Hang-Cheol Shin, Yeoun Jin Kim, Jong Hoon Hahn & Byung-Ha Oh (1998) “High resolution crystal structure of a human TNF-α mutant with low systemic toxicity”, Journal of Biological Chemistry, 273, 2153-2160

 

22.  Seung-Gu Chang, Dae-Young Kim, Ki-Doo Choi & Hang-Cheol Shin (1998) “Human insulin production from a novel mini-proinsulin which has a high receptor binding affinity”, Biochemical Journal, 329, 631-635

 

21.  Jinsil Seong, Hang-Cheol Shin, Gwi-Eon Kim & Chang-Ok Suh (1998) “Potentiation of antitumor effect by recombinant tumor necrosis factor-a”, Journal of the Korean Society for Therapeutic Radiology and Oncology, 16(3), 225-231

 

20.  Cheon-Soon Bae, Min-Sun Hong, Seung-Gu Chang, Dae-Young Kim & Hang-Cheol Shin (1997) “Optimization of fusion proinsulin production by high cell-density fermentation of recombinant E. coli”, Biotechnology and Bioprocess Engineering, 2, 27-32

 

19.  Ki-Doo Choi, Seung-Gu Chang & Hang-Cheol Shin (1997) “The role of highly conserved tetrapeptide sequence of C-peptide in the folding of proinsulin”, Bulletin of the Korean Chemical Society, 18, 798-800

 

18.  Hang-Cheol Shin (1997) “Interaction of myelin basic P2 protein and its peptide fragments with anionic detergent micelles”, Bulletin of the Korean Chemical Society, 18, 687-689

 

17.  Woojin Jeong, Nam-Kyu Shin & Hang-Cheol Shin (1997) “Bacterial chaperones increase the production of soluble human TNF-alpha in Escherichia coli”, Biotechnology Letters, 19, 579-582

 

16.   Hyung-Mee Han, Kyung-Hee Sohn, Hyun-Jeong Oh, Kyung-Baek Choi, Seung-Tae Chung, Yearn Sunwoo, Nam-Kyu Shin & Hang-Cheol Shin (1997) “Antigenicity studies of M3S tumor necrosis factor-a (M3S TNF) mutein”, Korean Journal of Toxicology, 13(3), 203-208

 

15.  Jinsil Seong, Christopher G. Maross, Nancy R. Hunter, Hang-Cheol Shin & Luka Milas (1997) “Potentiation of antitumor efficacy of paclitaxel by recombinant tumor necrosis factor-alpha”, Anti-cancer Drugs, 8, 80-87

 

14.  Dae-Young Kim, Nam-Kyu Shin, Seung-Gu Chang & Hang-Cheol Shin (1996) “Production of recombinant human glucagon in E. coli by a novel fusion protein approach”, Biotechnology Techniques, 10, 669-672

 

13.  Hang-Cheol Shin, Barbara Stuart & Ernest F. McFarlane (1996) “Conformation of an antigenic determinant for experimental autoimmune neuritis”, Biochemical and Biophysical Research Communications, 224, 5-9

 

12.  Won-Seok Oh, Hang-Cheol Shin, Nak-Cheol Jeong & Jae-Min Shin (1996) “Modeling of pharmacophore of angitensin-II by study of its nonpeptidic antagonists”, Bulletin of the Korean Chemical Society, 17, 182-188

 

11.  Hang-Cheol Shin & Ernest F. McFarlane (1995) “Conformation studies by circular dichroism and fluorescence spectroscopy of myelin P2 protein and two of its peptides”, Journal of Biochemistry and Molecular Biology, 28, 546-551

 

10.  Nam-Kyu Shin, Inkyung Lee, Seung-Koo Jang & Hang-Cheol Shin (1995) “Development of novel human tumor necrosis factor-alpha muteins” CRC Recent Advances in Cancer Research 1995, pp. 175-182

 

9.  Hang-Cheol Shin (1995) “Protein Engineering of TNF”, Bioforum, 3, 100-105

 

8.  Nam-Kyu Shin, Inkyung Lee, Seung-Koo Jang, Hang-Cheol Shin (1994) Development of novel human tumor necrosis factor-alpha muteins. Proc. BPERC Int. Symp. 43-50

 

7.  Jong-Nam Kim, Sung-Min Chung, Mi-Hyang Park, Hang-Cheol Shin & Inkyung Lee (1994) “The effect of tumor necrosis factor and anticancer chemotherapeutic agents on head and neck squamous cell carcinoma cell lines”, Korean Journal of Otolaryngology, 37, 1048-1058

 

6.  Hang-Cheol Shin, Gene Merutka, Jonathan P. Waltho, Linda L. Tennant, H. Jane Dyson & Peter E. Wright (1993) “Peptide models of protein folding initiation sites: 3. The G-H helical hairpin of myoglobin”, Biochemistry, 32, 6356-6364

 

5.  Hang-Cheol Shin, Gene Merutka, Jonathan P. Waltho, Peter E. Wright & H. Jane Dyson (1993) “Peptide models of protein folding initiation sites: 2. The G-H turn region of myoglobin acts as a helix stop signal”, Biochemistry, 32, 6348-6355

 

4.  Hang-Cheol Shin & Ernest F. McFarlane (1993) “Effect of phospholipids on the conformation of myelin P2 protein and its peptides”, Korean Biochemical Journal, 26, 163-167

 

3.   H. Jane Dyson, James R. Sayre, Gene Merutka, Hang-Cheol Shin, Richard A. Lerner & Peter E. Wright (1992) “Folding of peptide fragments comprising the complete sequence of proteins. Models for initiation of protein folding. II. Plastocyanin”, Journal of Molecular Biology, 226, 819-835

 

2.  Hang-Cheol Shin, Ernest F. McFarlane, John D. Pollard & Eilean G.S. Watson (1989) “Induction of experimental allergic neuritis with synthetic peptides from myelin P2 protein”, Neuroscience Letters, 102, 309-312

 

1.  Hang-Cheol Shin & Ernest F. McFarlane (1987) “The secondary structure of myelin P2 protein derived by secondary structure prediction methods, circular dichroism, and 400-MHz 1H-NMR spectroscopy: implications for tertiary structure”, Biochimica et Biophysica Acta, 913, 155-162

  

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