This page is intended as the home page for men proven or predicted to have the L645 mutation.
L645's discovery was in 2011 at the labs of Family Tree DNA.
The above diagram shows L645's position in the G tree. It is the youngest of a
series of mutations, each one covering fewer persons as the tree branched.
All L645 men have all the mutations shown above it in the tree.
A separate page exists for each of these mutations and the persons covered by them.
See tabs on left. The G-M406, G-P287 and G-M201 pages have significant additional
L645 has three sister subgroups, L14, M3302, PF3296. Men can belong to one of them,
but not to the other because each has some different ancestors. Perhaps a third of
M406 men belong to L645.
Almost all L645 men have the value of 9 at marker DYS578. This is not true with
the sister group of L14, but this 9 value is seen in other subgroups with M406
Age of L645
Comparing the 67 markers of L645 men, it seems the common male ancestor is
likely over 4,000 yrs old. Whole Y-DNA sequencing of L645 men will provide a much better
estimate of time events
Geographical Distribution of L645
The available L645 samples cover a wide geographical region, including Europe, the Middle
East, Turkey, and the countries south of the Caucasus Mountains. This pattern is not much
different from other men within M406. Possibly of significance, no samples within M406,
including L645, have surfaced from southern and central Asia and western China
where other G subgroups are found.
Berger et al. in 2013 in a large sampling of the Austrian population found no L645 samples.
Origins of L645
Little is known of the origins of L645. This question is even more difficult in the context of
similar geographical distributions of the other major M406 subgroups. Whole Y-DNA
sequencing should provide usual information to unravel the information about origins.
On the Project Roster, subgroups have their own maps. The L645 subgroup is listed at:
Look at top left of map and choose the L645 subgroup.
Sources of information
Berger and others in 2013 found no L645 in a large sampling of the Austrian
The following L645 men or predicted L645 men have the following results
for newer, poorly defined SNP mutations: [results may be from varied labs]
+ means positive, - means negative
L90- Arslan, Melik, Melik-Yolchyan
[several years after there discovery L373-L377 were never made available for testing]
more info about these SNPs can be found at:
type L1325, for example, in the Landmark box. After searching, look
for the small L1325 in the colored area and click on it.