Structural Glycobiology

Structural Biology Unit - CIC bioGUNE 
Technological Park of Bizkaia 
The Basque Country – Spain

We investigate the structural determinants and the modulation of substrate specificity of proteins involved in the biosynthesis and modification of glycans. We use a multidisciplinary approach including X-ray Crystallography, X-ray Free Electron Laser (XFEL), Cryo Electron Microscopy (Cryo-EM), Small Angle X-ray Scattering, Protein Biophysics, Protein Biochemistry and Molecular Biology, to elucidate mechanistic aspects of these processes at the molecular level.