Gammanol Forte

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*Please note that Biotics Research Corporation sells only to licensed health care professionals (M.D., D.O., D.C., N.D., etc.). To place an order please contact your local distributor, or contact a customer representative at (800) 231-5777.

Product Information:

Gammanol Forte™ supplies gamma oryzanol with FRAC® (registered trademark of Biotics Research Corporation), providing free ferulic acid with a complex mixture of polyphenolics, including free sterols and triterpenoids. It supports healthy growth hormone production and offers significant free-radical scavenging properties similar to that of sylimarin, as measured by its ability to quench the organic DPPH (1, 1 diphenyl 2 - picrylhydrazyl) free radical.


Each tablet supplies:

FRAC® (from rice) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 mg

Gamma Oryzanol (from rice) . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 mg

FRAC® is a mixture of water soluble, free transferulic acid and free sterols prepared from natural plant sources by an exclusive fractionation process developed by Biotics Research Corporation.

RECOMMENDATION: One (1) tablet three (3) times each day as a dietary supplement or as otherwise directed by a healthcare professional.

FRAC® is a registered trademark of Biotics Research Corporation.

Contains: 90 Tablets; 180 Tablets
Product #: 6710; 6711
NDC: 55146-06710; 55126-06711



Supplementation of Gammanol Forte has been shown to increase human growth hormone (HGH) production. Original research by David Brownstein, M.D. shows positive increases in serum insulin growth factor - 1 (lGF -1) in 8 out of 10 subjects, following supplementation with Gammanol Forte™. Levels of plasma IGF-1 correlate directly with changes in growth hormone production. Ten subjects, ages 29 - 77, participated in the study. Blood was drawn from each participant and IGF - 1 measured prior to beginning supplementation with Gammanol Forte™. Each participant took 2 Gammanol Forte™ tablets twice daily for 5 weeks. Blood was again drawn and IGF - 1 again measured at the same time of day and with no change to diet. A significant increase in serum IGF - 1 was seen in 9 out of 10 subjects following supplementation, with an average increase of 45%. Results suggest that supplementation with Gammanol Forte™ increases growth hormone production by 45%. More information can be found in one of Dr. Brownstein’s books: The Miracle of Natural Hormones.

Growth hormone promotes skeletal muscle development and hypertrophy by increasing protein uptake and storage as skeletal muscle tissue. It causes cells to switch from relying on carbohydrates for energy to burning fat by stimulating lipolysis (breakdown of stored fat). Growth hormone levels decline with age and this contributes to muscular atrophy by reducing protein storage, reduced bone mass resulting from decreasing stimulation of osteoblasts while leaving osteoclast activity uninhibited leading to osteoporosis, reduced cartilage maintenance and repair due to decreased stimulation of chondrocyte (cartilage cell) proliferation, and shorter cell life span and replication rate as a result of decreased cellular signaling to repair and build.

Gammanol Forte with FRAC has received much attention from the bodybuilding community as well as the elderly. This product has traditionally been used by bodybuilders because of its ability to increase lean muscle mass by increasing the natural release of Human Growth Hormone (HGH). However, often HGH is illegally purchased and subcutaneous injections are administered to bodybuilders and power lifters. This exogenous supplementation leads to a decrease in GH receptor sites and down regulation of somatotropin-releasing hormone production, which leads to a reduction in somatotropin (growth hormone), which in turn leads to a reduction in somatomedin A, B, and C, better known as IGF-2, vitronectin derivative, and IGF-1. High levels of IGF-1 also stimulate release of somatostatin, which directly inhibits GH production and release from the pituitary gland. In most cases involving subjects who supplement GH for more than six months, somatotropin production ceases completely and it very rarely returns to adequate levels even after several months without exposure to supplemental GH.   


Human growth hormone is directed toward increasing protein uptake and retention through synthesis of new muscle fibers and repairing damaged muscle cells. Studies, supported by clinical results, indicate that Gammanol Forte with FRAC is often useful with primary thyroid hypofunction and in cases of low GH production and hormone imbalance. Both the studies and the clinical results indicate the reason for these beneficial changes is the ability of Gamma Oryzanol and free transferulic acid (Gammanol Forte with FRAC) to help normalize pituitary function. There are several products in the marketplace that contain Gamma Oryzanol, however, only Biotics Research has the exclusive fractionation process that allows them to obtain the free sterols and free transferulic acid from plant sources. Use for muscular development and hypertrophy, osteoporosis, arthritis, menopausal symptoms, athletic training, athletic amenorrhea, muscular atrophy, wasting syndrome, severe burns, exposure to free radical generator such as chemicals and x-rays, elevated blood lipids, controlling blood pressure, hypoadrenia, gastritis, gastric ulcers, and severe nervous tension.


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