A1. Thomas Penruddock, of Arkeilby, in co. Cumberland, m. Agnes, daughter of Sir John Lowther, Knight.
  • B1. Robert Penruddock, of Arkeilby, m. Agnes, daughter of Sir William Ley, Knight.
    • C1. Edward Penruddock, of Arkeilby, m. Elizabeth, daughter of Robert Highmore, of Armathwayt, co. Cumberland.
      • D1. Robert Penruddock, of Hale, Wiltshire, m. Joyce, daughter of John Charnells, of Wishaw, co. Warwick; without issue.
      • D2. Anthony Penruddock, of Arkeilby, m. a daughter of William English, of Owterside, co. Cumberland.
        • E1. John Penruddock.
      • D3. George Penruddock, of Hales, Wiltshire, m. 1stly Elizabeth, daughter of William Aprice, of Falston, Wiltshire; m. 2ndly Ann, widow of John Cock.
        • E1. *by 1* Edward Penruddock.
        • E2. *by 1* Robert Penruddock.
      • D4. Elizabeth Penruddock, m. Thomas Bowman.
      • D5. Mary Penruddock, m. 1stly John Ley, Esq.; m. 2ndly to Cuthbert Musgrave.
  • B2. Henry Penruddock.
  • B3. Alexander Penruddock.

Arms: Quarterly, 1st Gules, a bend raguley argent; 2nd Per chevron sable and ermine, in chief two boars' heads couped; 3rd Sable, six annulets, two, two, and two, or; 4th Azure, a fesse between three martlets or.
Crest: A demi-dragon between two eagles' wings displayed or.

Sources: Foster, J. (ed) Pedigrees Recorded at the Heralds' Visitations of the Counties of Cumberland and Westmorland, of 1615 and 1666. London: The Harleian Society.