Overview

EVOGREN stands for "Evolution of Gene Regulatory Networks". It is a project designed to study the intersection between Population Genetics and Gene Regulatory Networks.

Our main goal is to study how a population of gene regulatory networks evolves over time. The related evolutionary forces are random genetic drift and positive selection. We are interested in both the properties of the network, for example the total number of positive regulatory interactions, the size of the network, the distribution of regulatory interactions per gene, and the evolution of the cis-regulatory elements that mediate the interactions between genes.


http://upload.wikimedia.org/wikipedia/commons/b/b4/The_protein_interaction_network_of_Treponema_pallidum.png
The Treponema pallidum protein interactome (source: Wikipedia, http://en.wikipedia.org/wiki/Interactome).The Binary Protein Interactome of Treponema pallidum – the Syphilis Spirochete