"Early Caffeine for Neuroprotection

in Preterm Neonates:


Our latest publications related to the Espresso Study:

  • PMID 31812154: Long term effects of caffeine in the preterm rabbit

  • PMID 31767227: Quantification of caffeine in cerebrospinal fluid of preterm infants

The Espresso study...

  1. A validated animal model will be used to study the pharmacokinetics of caffeine and its effects on neurological outcomes such as brain magnetic resonance imaging and behavioral tests.

  2. Subsequently the efficacy and safety of caffeine will be assessed in a clinical trial in very preterm infants.

General informations about Espresso study are presented here:

1. the research team

2. why "espresso study"

3. background

4. pre-clinical study

5. clinical study

6. why this website

7. contact us