Ph.D Ecology and Evolutionary Biology

My research interests focus on the field of Ecological Immunology and Evolutionary Biology. I am developing research projects on environmental and genetic factors that shape the multiple host and parasite communities interactions and their evolution.


2007/2010    PhD thesis. Ecology and Evolutionary Biology. University of Montpellier II (Languedoc-Roussillon, France). Center for Biology and Management of Populations (CBGP)

2005 / 2007    Master’s degree. Biology and Evolution. University of Dijon (Bourgogne, France).

2002 / 2005  Bachelor’s degree. Biology and Ecology. University of Besançon (Franche-Comté, France).


2016 - present   Postdoctoral position at the institut méditerranéen de biodiversité et d'écologie (IMBE), University AIx Marseille. Insights into the diversity of microbiota in the Chondrostoma complex species. Collaborators: Drs. André Gilles & JF Martin 

2012 / 2015  Postdoctoral position at the laboratory Biogeosciences Joint Research Unit (CNRS, University of Burgundy, France). Evolution of Immune Regulation (ANR EVOREGIM). . Collaborators:  Pr. Bruno Faivre & Dr. Gabriele Sorci .

2007 / 2010  Ph.D position at the Center for Biology and Management of Populations. (Montpellier, France) on the project: Variability of resistance/tolerance to Puumala hantavirus in bank voles and epidemiological consequences. Supervision: Dr. Nathalie Charbonnel

2006 / 2007  Master Research at the laboratory Biogeosciences Joint Research Unit, research group Ecology and Evolution (Dijon, France) on the project: Variability of resistance to Plasmodium in wild populations of house sparrows Passer domesticus. Role of Mhc gene diversity and antioxidant capacity. Supervision: Dr. Gabriele Sorci.


1. Galan M., Guivier E., Caraux G., Charbonnel N. and Cosson JF. 2010. A 454 Multiplex sequencing method for rapid and reliable genotyping of highly polymorphic genes in large scale studies. BMC Genomics. 11, 296

2. Guivier E., Galan M., Malé P.J.G., Kallio E., Voutilainen L., Henttonen H., Olsson G.E., Lundkvist A., Tersago K., Augot D., Cosson J.F. and Charbonnel N. 2010. Associations between Mhc genes and Puumala virus infection in Myodes glareolus are detected in wild populations, but not from experimental infection data. Journal of General Virology. 91, 2507-2512.

3. Guivier E., Galan M., Ribas Salvador A., Chaval Y., Xuéreb A., Olsson G.E., Essbauer S., Henttonen H., Voutilainen L., Cosson J. F. and Charbonnel N. 2010. Tnf-α expression and promoter sequences reflect the balance of tolerance/resistance to Puumala hantavirus infection in European bank vole  populations. Infection Genetics and Evolution. 10(8):1208-17

4. Meglécz E., Piry S., Desmarais E., Galan M., Gilles A., Guivier E., Pech N. and Martin J-F. 2011. SESAME (SEquence Sorter & AMplicon Explorer): Genotyping based on high-throughput multiplex amplicon sequencing. Bioinformatics. 15; 27(2): 277–278

5. Guivier E. *, Ribas Salvador A.*, Xuereb A., Chaval Y., Cadet P., Poulle ML., Sironen T., Voutilainen L., Henttonen H., Cosson J.F. & Charbonnel N. 2011. Concomitant influence of helminth infection and landscape configuration on the distribution of Puumala hantavirus in its reservoir, Myodes glareolus. BMC Microbiology. 11: 3; * : equivalent contributions

6. Guivier E., Galan M, Chaval Y., Xuereb A., Poulle ML, Henttonen H., Voutilainen L., Charbonnel N. & Cosson J.F. 2011. Landscape genetics highlights the role of bank vole metapopulation dynamics in the epidemiology of Puumala hantavirus. Molecular Ecology, 20, 17, 3569-3583

7. Piry S., Guivier E., Realini A. and Martin J-F. 2012. |SE|S|AM|E| Barcode: NGS-oriented software for amplicon characterization – application to species and environmental barcoding. Molecular Ecology Resources. doi: 10.1111/j.1755-0998.2012.03171

8.  Vayssier-Taussat M., Le Rhun D., Buffet J-P, Maaoui N., Guivier E., Galan M., Charbonnel N., Cosson J-F. 2012. Detection of the novel human pathogen “Candidatus Neoehrlichia mikurensis” in wild rodents, France. Emerging Infectious Diseases. 18(12): 2063-2065

9.  Rohtfritsch A., Guivier E., Galan M., Chaval Y., Cosson J-F., Charbonnel N. (2013, n°2). Apport de l'immunogénétique à la compréhension des intéractions entre le campagnol roussâtre Myodes glareolus et l'hantavirus Puumala. Bulletin de l'Académie vétérinaire de France.

10. Guivier E., Galan M., Henttonen H., Cosson J-F, Charbonnel N. 2014. Landscape features and helminth co-infections shape the bank vole immunoheterogeneity with consequences for Puumala epidemiology. Heredity. 112: 274-281. doi:10.1038/hdy.2013.1

11.  Lippens C., Guivier E., Faivre B., Sorci G. 2016. Reaction norms of host immunity, fitness, and parasite performance in a mouse – intestinal nematode interaction. International Journal of Parasitology. 46,2: 133-140

12.  Guivier E., Bellenger J., Sorci G., Faivre B. 2016. Helminthes interactions with the host immune system: Short-term benefits and costs in relation to the infectious environment.The American Naturalist. 188, 2 

13.  Dubois A., Galan M., Cosson J-F., Gauffre B., Henttonen H., Niemimaa J., Razzauti M., Voutilainen L., Vitalis R., Guivier E. & Charbonnel N. 2017. Microevolution of bank Voles (Myodes glareolus) at neutral and immune related  genes during multiannual dynamic cycles: consequences for Puumala hantavirus epidemiology. Infection, Genetics and Evolution  49, 318-329

14   Guivier E., Lippens C., Faivre B., Sorci G. 2017. Plastic and micro-evolutionary responses of a nematode to the host immune environment. Experimental Parasitology. 181, 14-22

15.  Lippens C., Guivier E., Faivre B., Sorci G. (in press). Life-history adjustments to intestinal inflammation in a gut nematode. Journal of Experimental Biology

16.  Guivier E., Martin JF., Pech N., Ungaro A., Chappaz R., Gilles A.(in press) Microbiota diversity within and between the tissues of two wild interbreeding species.Microbial Ecology

17Guivier E., Crisuolo F., Zhan S., Bellenger J., Galan M., Faivre B., Sorci G. Early life infection and host senescence. (under review)


  • Sorci G., Guivier E, Lippens C., Faivre B. Microbes, parasites and immune diseases. 2016.  In: Evolutionary thinking in medicine: from research to policy and practice (Eds. A. Alvergne, C. Faurie, C. Jenkinson), Springer.


  • Guivier E.  2010. Variabilité de la résistance/tolérance du campagnol roussâtre à l'hantavirus Puumala et conséquences épidémiologiques. Thesis. Université Montpellier II, France.

REFEREE for Molecular Ecology, Proceedings of the Royal Society B, Infection Genetics and Evolution, Plos One, Biological Journal of the Linnean Society


Guivier E., Galan M., Cosson J.F. and Charbonnel N. The role of Mhc gene polymorphism in bank vole to the resistance to Puumala hantavirus. International conference of EDEN research program (Emerging Vector-borne Diseases in a Changing European Environment), Brno (Czech republic), January 2008. (oral communication)

Guivier E., Galan M., Cosson J.F. and Charbonnel N. Immunogenetic approaches in wild natural populations: Application to emergent zoonoses.The case of Puumala Hantavirus and its reservoir Myodes glareolus. 12th Congress of European of the European Society of Evolutionary Biology, Turin (Italy), August 2008. (poster)

Guivier E., Galan M., Cosson J.F. and Charbonnel N. Immunogenetic in wild population reservoir: a key for landscape epidemiology. International conference of EDEN research program (Emerging Vector-borne Diseases in a Changing European Environment, Montpellier (France), May 2010. (oral communication)

Guivier E., Galan M., Cosson J.F. and Charbonnel N. Population genetics of Tnf-α gene reveals selection mediating a balance of tolerance/resistance to Puumala virus in bank voles. Annual Meeting of the Society for Molecular Biology and Evolution, Lyon (France), July 2010. (poster)

Guivier E., Galan M., Cosson J.F. and Charbonnel N. Variability of resistance/tolerance to Puumala hantavirus in bank voles and the epidemiological consequences. Invited speaker by Pr Milinski at the Max Planck Institute, Plön (Germany), September 15th 2011.

Guivier E., Bellenger J., Faivre B., Sorci G. Immunopathological cost of chronic inflammation in relation to inflammatory stimulation. Annual RCNE meeting (Research Collaborative Network in Ecoimmunology), Woods Hole (MA, USA) May 2014. (oral communication)

Guivier E., Bellenger J., Faivre B., Sorci G. Immune system interference by parasite: cost and benefit in relation to infectious context. Conférence Jacques Monod Sept 2014


Guivier E., Galan M., Cosson JF and Charbonnel N. Tnf-α gene expression polymorphism in bank vole: consequences for Puumala hantavirus epidemiology at the landscape scale. Ist congress of Ecology, Montpellier (France), September 2010. (oral communication).

Guivier, E., Faivre, B., Sorci, G. Environmental effect on the cost of chronic infection by Heligmosomoides polygyrus in mouse. National Congress REID (Réseau de l'Ecologie des Interactions Durable). Montpellier, February 2014. (oral communication)


2008   PhD student Fellowship “Bourse de mobilité internationale”. University Montpellier II (France). Courses in serological and immunological methods. Detection of viral infection and participation to field collection of virus samples in central Finland. (METLA and Haartman institute).

2009   Laureate of the “Bourse de recherches Jean & Marie-Louise Dufrenoy”. The French society of agriculture. Project: Role of immune gene polymorphism in bank vole on the geographic distribution of Puumala hantavirus in Sweden. (Swedish University of Agricultural Sciences, Umeå)

CNRS/ Marseille


Passer domesticus

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Plasmodium relictum

Myodes glareolus

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Mus musculus


Plasmodium yoelii

Chondrostoma nasus
Chondrostoma nasus

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