autoHGPEC

Identification of novel disease-gene and disease-disease associations is an important task in biomedical research. Recently, we have developed a Cytoscape app, namely HGPEC, using a state-of-the-art network-based method for such the task. Here, we describe an upgrading version of HGPEC, namely autoHGPEC, with added automation features. By adding these features, autoHGPEC can be used as a component of other complex analysis pipelines as well as make use of other data resources. We demonstrated the use of AutoHGPEC by predicting novel breast cancer-associated genes and diseases. Further investigation by visualizing and collecting evidences for associations between top 20 ranked genes/diseases and breast cancer has shown the ability of autoHGPEC.
Ċ
Hau Le Duc,
Apr 24, 2018, 2:19 AM
ċ
autoHGPEC-v1.1.jar
(4865k)
Hau Le Duc,
Apr 24, 2018, 10:37 AM
ċ
check-cytoscape-connection-autoHGPEC.R
(3k)
Hau Le Duc,
Apr 23, 2018, 7:26 AM
Comments