Drugan R C; Stafford N P; Warner T A
Preclinical evidence for the benzodiazepine receptor involvement in the pathophysiology of PTSD, comorbid substances abuse, and alcoholism. 
                                           Post-traumatic stress disorder: From neurobiology to treatment (Book Chapter) in press

Stafford N P; Jones A M; Drugan R C
Ultrasonic vocalizations during intermittent swim stress forecasts resilience in a subsequent juvenile social exploration test of anxiety.
Behavioural brain research 2015;287:196-199.

Benassi V A; Drugan R C; Fuld K; Gibson B K; Leichtman M D
Preparing future psychology faculty at the University of New Hampshire. 
                                           Preparing the new psychology professorate: Helping graduate students                                       become competent teachers (Book Chapter) 2014;70-75.

Christianson J P; Flyer-Adams J G; Drugan R C; Amat J; Daut R A; Foilb A R; Watkins L R; Maier S F
Learned stressor resistance requires extracellular signal-regulated kinase in the prefrontal cortex.
Frontiers in behavioral neuroscience 2014;8(348):1-11.

Drugan R C; Warner T A; Papallo T A; Castracane L L; Stafford N P
Ultrasonic vocalizations during intermittent swim stress forecasts resilience in subsequent forced swim and spatial learning tests.
Behavioural brain research 2014;259:41-44.

Christianson J P; Drugan R C; Flyer J G; Watkins L R; Maier S F
Anxiogenic effects of brief swim stress are sensitive to stress history.
Progress in neuro-psychopharmacology and biological psychiatry 2013;44:17-22. 

Drugan R C; Christianson J P; Warner T A; Kent S
Resilience in shock and swim stress models of depression.
Frontiers in behavioral neuroscience 2013;7(14):1-8.

Drugan R C; Hibl P T; Kelly K J; Dady K F; Hale M W; Lowry C A
Prior cold water swim stress alters immobility in the forced swim test and associated activation of serotonergic neurons in the rat dorsal raphe nucleus.
Neuroscience 2013;253:221-234.

Warner T A; Libman M K; Wooten K L; Drugan R C
Sex differences associated with intermittent swim stress.
Stress 2013;16(6):655-663.

Warner T A; Stafford N P; Rompala G R; Van Hoogenstyn A J; Elgert E; Drugan R C
Intermittent swim stress causes Morris water maze performance deficits in a massed-learning trial procedure that are exacerbated by reboxetine.
Pharmacology, biochemistry, and behavior 2013;113:12-19.

Eren S; Drugan R C; Hazi A; Flannery G; Kent S
Coping in an intermittent swim stress paradigm compromises natural killer cell activity in rats.
Behavioural brain research 2012;227(1):291-294.

Warner T A; Drugan R C
Morris water maze performance deficit produced by intermittent swim stress is partially mediated by norepinephrine.
Pharmacology, biochemistry, and behavior 2012;101(1):24-34.

Stiller A L; Drugan R C; Hazi A; Kent S P
Stress resilience and vulnerability: the association with rearing conditions,endocrine function, immunology,and anxious behavior.
Psychoneuroendocrinology 2011;36(9):

Drugan R C; Macomber H; Warner T A
Intermittent and continuous swim stress-induced behavioral depression: sensitivity to norepinephrine- and serotonin-selective antidepressants.
Psychopharmacology 2010;212(1):85-91.

Drugan R C; Christianson J P; Stine W W; Soucy D P
Swim stress-induced ultrasonic vocalizations forecast resilience in rats.
Behavioural brain research 2009;202(1):142-145.

Christianson J P; Rabbett S; Lyckland J; Drugan R C
The immobility produced by intermittent swim stress is not mediated by serotonin.
Pharmacology, biochemistry, and behavior 2008;89(3):412-423.

Drugan R C; Wiedholz L M; Holt A; Kent S; Christianson J P
Environmental and immune stressors enhance alcohol-induced motor ataxia in rat.
Pharmacology, biochemistry, and behavior 2007;86(1):125-131.

Levay E A; Govic A; Hazi A; Flannery G; Christianson J; Drugan R C; Kent S
Endocrine and immunological correlates of behaviorally identified swim stress resilient and vulnerable rats.
Brain, behavior, and immunity 2006;20(5):488-497.

Christianson J P; Drugan R C
Intermittent cold water swim stress increases immobility and interferes with escape performance in rat.
Behavioural brain research 2005;165(1):58-62.

Drugan R C; Eren S; Hazi A; Silva J; Christianson J P; Kent S
Impact of water temperature and stressor controllability on swim stress-induced changes in body temperature, serum corticosterone, and immobility in rats.
Pharmacology, biochemistry, and behavior 2005;82(2):397-403.

Tayyabkhan Tara R; Mammola Bianca N; Drugan Robert C
A comparison of female and male rats' ETOH-induced ataxia and exploration following restraint or swim stress.
Pharmacology, biochemistry, and behavior 2002;72(1-2):335-342.

Brown P L; Hurley C; Repucci N; Drugan R C
Behavioral analysis of stress controllability effects in a new swim stress paradigm.
Pharmacology, biochemistry, and behavior 2001;68(2):263-272.

Drugan R C
Rodent models of depression: Learned helplessness using a triadic design in rats.
Current protocols in neuroscience 2001;Supplement 14:8.10B.1-8.10B.12.

Drugan R C
The neurochemistry of stress resilience and coping: A quest for nature's own antidote to illness.
The science of optimism and hope (Book Chapter) 2000;57-71.

Austin M; Myles V; Brown P L; Mammola B; Drugan R C
FG 7142- and restraint-induced alterations in the ataxic effects of alcohol and midazolam in rats are time dependent.
Pharmacology, biochemistry, and behavior 1999;62(1):45-51.

Burk J A; Glode B M; Drugan R C; Mair R G
Effects of chlordiazepoxide and FG 7142 on a rat model of diencephalic amnesia as measured by delayed-matching-to-sample performance.
Psychopharmacology 1999;142(4):413-420.

Drugan R C
Coping with traumatic stress interferes with memory of the event: A new conceptual mechanism for the protective effect of stress control
Trauma and Memory (Book Chapter) 1999; 245-256.

Drugan R C; Basile A S; Ha J H; Healy D; Ferland R J
Analysis of the importance of controllable versus uncontrollable stress on subsequent behavioral and physiological functioning.
Brain research. Brain research protocols 1997;2(1):69-74.

Drugan R C
Peripheral benzodiazepine receptors: molecular pharmacology to possible physiological significance in stress-induced hypertension.
Clinical neuropharmacology 1996;19(6):475-496.

Drugan R C; Coyle T S; Healy D J; Chen S
Stress controllability influences the ataxic properties of both ethanol and midazolam in the rat.
Behavioral neuroscience 1996;110(2):360-367.

Ha J H; Pannell L; Drugan R C; Ferland R; Basile A S
Extraction of benzodiazepine receptor ligands from mammalian tissues.
Neuroscience protocols 1996;60(2):1-12.

Healy D J; Drugan R C
Escapable stress modulates retention of spatial learning in rats: preliminary evidence for involvement of neurosteroids.
Psychobiology 1996;24(2):110-117.

Drugan R C; Holmes P V; Scher D M; Luczak S; Oh H; Ferland R J
Environmentally induced changes in peripheral benzodiazepine receptors are stressor and tissue specific.
Pharmacology, biochemistry, and behavior 1995;50(4):551-562.

Drugan R C
Are the nonmitochondrial peripheral benzodiazepine receptors on leukocytes a novel intermediary of brain, behavior, and immunity?
Laboratory investigation 1994;70(1):1-5.

Drugan R C; Basile A S; Ha J H; Ferland R J
The protective effects of stress control may be mediated by increased brain levels of benzodiazepine receptor agonists.
Brain research 1994;661(1-2):127-136.

Holmes P V; Drugan R C
Stress-induced regulation of the renal peripheral benzodiazepine receptor: possible role of the renin-angiotensin system.
Psychoneuroendocrinology 1994;19(1):43-54.

Drugan R C; Park R; Kaufman L; Holmes P V
Etiology of the sexual dimorphism in renal peripheral benzodiazepine receptor response to stress in rats.
Hormones and behavior 1993;27(3):348-365.

Drugan R C; Paul S M; Crawley J N
Decreased forebrain [35S]TBPS binding and increased [3H]muscimol binding in rats that do not develop stress-induced behavioral depression.
Brain research 1993;631(2):270-276.

Holmes P V; Drugan R C
Amygdaloid central nucleus lesions and cholinergic blockade attenuate the response of the renal peripheral benzodiazepine receptor to stress.
Brain research 1993;621(1):1-9.

Meng I D; Drugan R C
Sex differences in open-field behavior in response to the beta-carboline FG 7142 in rats.
Physiology & behavior 1993;54(4):701-705.

Drugan R C; Scher D M; Sarabanchong V; Guglielmi A; Meng I; Chang J; Bloom K; Sylvia S; Holmes P
Controllability and duration of stress alter central nervous system depressant-induced sleep time in rats.
Behavioral neuroscience 1992;106(4):682-689.

Holmes P V; Drugan R C
Angiotensin II rapidly modulates the renal peripheral benzodiazepine receptor.
European journal of pharmacology 1992;226(2):189-190.

Holmes P V; Stringer A P; Drugan R C
Impact of psychological dynamics of stress on the peripheral benzodiazepine receptor.
Pharmacology, biochemistry, and behavior 1992;42(3):437-444.

Drugan R C; Holmes P V
Central and peripheral benzodiazepine receptors: involvement in an organism's response to physical and psychological stress.
Neuroscience and biobehavioral reviews 1991;15(2):277-298.

Drugan R C; Holmes P V; Stringer A P
Sexual dimorphism of stress-induced changes in renal peripheral benzodiazepine receptors in rat.
Neuropharmacology 1991;30(4):413-416.

Holmes P V; Drugan R C
Differential effects of anxiogenic central and peripheral benzodiazepine receptor ligands in tests of learning and memory.
Psychopharmacology 1991;104(2):249-254.

Drugan R C; Holmes P V; Stringer A P
Pentobarbital blocks the stress-induced decrease in [3H]Ro 5-4864 binding in rat kidney.
Brain research 1990;535(1):151-154.

Drugan R C; Deutsch S I; Weizman A; Weizman R; Vocci F J; Crawley J N; Skolnick P; Paul S M
Molecular mechanisms of stress and anxiety: alterations in the benzodiazepine/GABA receptor complex.
Frontiers of stress research (Book Chapter) 1989;148–159.

Drugan R C; Morrow A L; Weizman R; Weizman A; Deutsch S I; Crawley J N; Paul S M
Stress-induced behavioral depression in the rat is associated with a decrease in GABA receptor-mediated chloride ion flux and brain benzodiazepine receptor occupancy.
Brain research 1989;487(1):45-51.

 Drugan R C; Skolnick P; Paul S M; Crawley J N
A pretest procedure reliably predicts performance in two animal models of inescapable stress.
Pharmacology biochemistry and behavior 1989;33(3):649-654.

Deutsch S I; Drugan R C; Vocci F J; Weizman A; Weizman R; Crawley J N; Skolnick P; Paul S M
The benzodiazepine-GABA receptor complex in experimental stress, anxiety, and depression.
New concepts in depression (Book Chapter) 1988;351-362.

Drugan R C; Basile A S; Crawley J N; Paul S M; Skolnick P
Characterization of stress-induced alterations in [3H] Ro5-4864 binding to peripheral benzodiazepine receptors in rat heart and kidney.
Pharmacology biochemistry and behavior 1988;30(4):1015-1020.

Drugan R C; Basile A S; Crawley J N; Paul S M; Skolnick P
“Peripheral” benzodiazepine binding sites in the maudsley reactive rat: selective decrease confined to peripheral tissues.
Brain research bulletin 1987;18(1):143-145.

Drugan R C; Crawley J N; Paul S M; Skolnick P
Buspirone attenuates learned helplessness behavior in rats.
Drug development research 1987;10:63-68.

Drugan R C; Basile A S; Crawley J N; Steven M. Paul; Phil Skolnick
Inescapable shock reduces [3H]Ro 5-4864 binding to 'peripheral-type' benzodiazepine receptors in the rat.
Pharmacology biochemistry and behavior 1986;24(6):1673-1677.

Drugan R C; Maier S F
Control versus lack of control over aversive stimuli: Nonopioid-opioid analgesic consequences.
National institute on drug abuse research monograph series 1986;74:71-89.

Drugan R C; Skolnick P; Paul S M; Crawley J N
Low doses of muscimol produce anticonflict actions in the lateral septum of the rat.
Neuropharmacology 1986;25(2):203-205.

Drugan R C; Ader D N; Maier S F
Shock controllability and the nature of stress-induced analgesia
Behavioral neuroscience 1985;99(5):791-801.

Drugan R C; Maier SF; Skolnick P; Paul S M; Crawley JN
An anxiogenic benzodiazepine receptor ligand induces learned helplessness.
European journal of pharmacology 1985;113(3):453-457.

Drugan R C; McIntyre T D; Alpern H P; Maier S F
Coping and seizure susceptibility: control over shock protects against bicuculline-induced seizures.
Brain research 1985;342(1):9-17.

Drugan R C; Ryan S M; Minor T R; Maier S F
Librium prevents the analgesia and shuttlebox escape deficit typically observed following inescapable shock.
Pharmacology biochemistry and behavior 1984;21(5):749-754.

Watkins L R; Drugan R C; Hyson R L; Moye T B; Ryan S M; Mayer D J; Maier S F
  Opiate and non-opiate analgesia induced by inescapable tail-shock: Effects of dorsolateral funiculus lesions and decerebration.
Brain research 1984;291):325-336.

Williams J L; Drugan R C; Maier S F
Exposure to uncontrollable stress alters withdrawal from morphine.
Behavioral neuroscience 1984;98(5):836-846.

Drugan R C; Maier S F
Analgesic and opioid involvement in the shock-elicited activity and escape deficits produced by inescapable shock.
Learning and motivation 1983;14(1):30-47.

Laudenslager M L; Ryan S M; Drugan R C; Hyson R L; Maier S F
Coping and immunosuppression: Inescapable but not escapable shock suppresses lymphocyte proliferation.
Science 1983;221:568-570.

MacLennan A J; Drugan R C; Maier S F
Long-term stress-induced analgesia blocked by scopolamine.
Psychopharmacology 1983;80(3):267-268.

Maier S F; Drugan R C; Grau J W; Hyson R L; MacLennan A J; Moye T B; Madden J; Barchas J D
Learned helplessness, pain and the endogenous opiates.
Advances in the analysis of behavior (Book Chapter) 1983; 275-332.

Drugan R C; Maier S F
The nature of the activity deficit produced by inescapable shock.
Animal learning & behavior 1982;10(3):401-406.

Drugan R C; Moye T B; Maier S F
Opioid and nonopioid forms of stress-induced analgesia: some environmental determinants and characteristics.
Behavioral and neural biology 1982;35(3):251-264.

Hyson R L; Ashcraft L J; Drugan R C; Grau J W; Maier S F
Extent and control of shock affects naltrexone sensitivity of stress-induced analgesia and reactivity to morphine.
Pharmacology biochemistry and behavior 1982;17(5):1019-1025.

MacLennan A J; Drugan R C; Hyson R L; Maier SF; Madden J; Barchas J D
Corticosterone: a critical factor in an opioid form of stress-induced analgesia.
Science 1982;215:1530-1532.

MacLennan A J; Drugan R C; Hyson R L; Maier SF; Madden J; Barchas J D
Dissociation of long-term analgesia and the shuttlebox escape deficit caused by inescapable shock.
Journal of comparative and physiological psychology 1982;96(6):904-912.

Maier S F; Drugan R C; Grau J W
Controllability, coping behavior, and stress-induced analgesia in the rat.
Pain 1982;12(1):47-56. 

Drugan R C; Grau J W; Maier S F; Madden J; Barchas J D
Cross tolerance between morphine and the long-term analgesic reaction to inescapable shock.
Pharmacology biochemistry and behavior 1981;14(5):677-682.

Maier S F, Drugan R C; Hyson R L; MacLennan A J; Madden J; Barchas J D
Opioid and nonopioid mechanisms of stress-induced analgesia.
Advances in endogenous and exogenous opioids (Book Chapter) 1981;270-272.

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University of New Hampshire
Robert Drugan's Lab