Breast-Fibrocystic Change-Risk Factors for Cancer
 
  
Table 1. Relative Risk for Invasive Breast Carcinoma Based on Pathologic Examination of Benign Breast Tissue
Patrick L. Fitzgibbons, MD; Donald F. Henson, MD; Robert V P Hutter, MD; for the Cancer Committee of the College of American Pathologists.  Benign Breast Changes and the Risk for Subsequent Breast Cancer An Update of the 1985 Consensus Statement. Arch Pathol Lab Med. 1998;122:1053—1055
No Increased Risk
Women with the following lesions are at no greater risk for invasive breast carcinoma than women who have not had a breast biopsy:
·        Adenosis other than sclerosing adenosis
·        Duct ectasia
·        Fibroadenoma without complex features see note A’
·        Fibrosis
·        Mast it is
·        Mild hyperplasia without atypia (see note B)
·        Ordinary cysts gross or microscopic:
·        Simple apocrine metaplasia (no associated hyperplasia or adenosis
·        Squamous metaplasia
Slightly Increased Risk (1.5—2.0 Times)
Women with the following lesions have a slightly increased risk for invasive breast carcinoma compared with women who have not had a breast biopsy:
·        Fibroadenoma with complex features see note M
·        Moderate or florid hyperplasia without atypia
·        Sclerosing adenosis see note C
·        Solitary papilloma without coexistent atypical hyperplasia (See note D)
Moderately Increased Risk (4.0—5.0 Times)
Women with the following lesions have a moderately in­creased risk for invasive breast carcinoma compared with wom­en who have not had a breast biopsy:
·        Atypical ductal hyperplasia [see notes B and F~
·        Atypical lobular hyperplasia
Markedly Increased Risk (8.0—10.0 Times)
Women with the following lesions have a high risk tor invasive breast carcinoma compared with women who have not had a breast biopsy:
·        Ductal carcinoma in situ (note F)
·        Lobular carcinoma in situ
Updated / Reviewed 2001-08-13