Dr Gautam Panda
Principal Scientist and Group Leader 
Medicinal and Process Chemistry Division
CSIR-CDRI (Central Drug Research Institute )
Sector-10, Jankipuram Extension, Sitapur Road, Lucknow-226031
Phone (Office) : 0522-2772450, 2772550, Ext. 4661, 4662
Phone (Res.) : 0522-2746635
Fax : 0522-2771941
Email : gautam.panda@gmail.com, gautam_panda@cdri.res.in
http://www.cdri.res.in/1547.aspx?id=1547
https://scholar.google.co.in/citations?user=YwJvoiIAAAAJ&hl=en

http://www.ncbi.nlm.nih.gov/pubmed/?term=gautam+panda

Citation indices

All

Since 2012

Citations

1535

963

h-index

23

18

i10-index

48

38

Academic Background :

 Ph.D. University of Hyderabad, with Professor Goverdhan Mehta (1999)
 M. Sc. Indian Institute of Technology (IIT) Kharagpur (1993)
 B. Sc. Ramakrishna Mission Residential College, Narendrapur of Calcutta University 


Current Broad Area of Research

  • Synthetic Organic Chemistry, Bioorganic and Medicinal Chemistry, Chemical Biology, Chemo and Bioinformatics, Advanced Pharmaceutical Ingredients (API), Innovative Process for Blockbuster Drugs

Sub Area of Research

  • Novel Process Research For Blockbuster Drugs

  • Treprostinil {Pulmonary Arterial Hypertension, Prostaglandin I2 receptor agonists}

  • Sorafenib {Multi Targeted Kinase Inhibitor}

  • Empagliflozin {Sodium Glucose Co-transporter 2 Inhibitor for Type 2 Diabetes}

  • Sunitinib {Tyrosine Kinase Inhibitor in Renal Cell carcinoma}  

  • Bedaquiline {Mycobacterium Tuberculosis ATP Synthase Inhibitor}


Postdoctoral Research: I was involved in Solid Phase Synthesis (SPS) of heterogeneous catalysts and their development as new catalytic systems for exhibiting enhanced reactivity. A bio-mimetic approach in designing Rh-based heterogenized catalysts that exhibited prolonged activity during hydroformylation reactions was developed

Doctoral Research: I was involved in multi-step organic transformations for total synthesis of Buckminsterfullerene (C60). Several new and conceptually simple approaches to fullerene fragments (bucky-bowls) that can be applied to fullerenes (bucky-balls) have been conceived and explored


Research Experience :

 Academic Title Institution Year
 Scientist  CDRISince Feb. 2002
JSPS Invitation Fellowship Program National Centre for Molecular Scale Nanoscience, Institute for Molecular Science Myodaiji, Okazaki, Japan ( with Prof. Hidehiro Sakurai) Sept2011-
 July    2012
INSA, India - DFG, Germany     Exchange Fellowship  University of Duesseldorf ( with Prof. Matthias Kassack )2007 (3 Months)
 Visiting FellowNational Chiao Tung Univ., Hsinchu, Taiwan ( with Prof. Tse Lok Ho) ; NSERC Visiting Postdoctoral Fellow, Department of Chemistry, Univ. of Ottawa (with Prof. Howard Alper and National Research Council, Ottawa, Canada (with Prof. Prabhat Arya ) Aug. 1999- 
June 2001

Awards/Fellowships :


JSPS  Invitation Fellowship Program for Research in Japan (2011-2012)
Chemical Research Society of India Bronze medal in Chemistry (2012)
CDRI Incentive Award in Chemical sciences from CDRI, Lucknow (2007, 2008, 2009)
Visited Heinerich Heine University, Duesseldorf, Germany for three months under Indian National Science Academy, India - DFG, Germany Exchange Fellowship Programme.

Teaching and Coordinating Experience :

Teaching for the course work under Chemical Science for the candidates working at CDRI, Lucknow and registered for Ph.D. either in Jawaharlal Nehru University (JNU), New Delhi or Academy of Scientific and Innovative Research (AcSIR), New Delhi as part of the Ph.D. program.

Courses being taught: a) Conformational Analysis b) Reactive Intermediates c) Chemistry and Biology of Heterocycles d) Selected reagents for organic synthesis e) Methods for stereoselective synthesis f) Selected name reactions g) structure based drug design h) Introduction and Advances in Chemical Biology i) Green and Sustainable Chemistry j) Natural products and drug discovery

Taught for the course work on “Logic in Organic Synthesis-I (MC-520, 3 credits) in Semester-I and “Logic in Organic Synthesis-II (MC-620, 3 credits) in Semester-II at NIPER, Raebareli from 2010 to 2014

Course Coordinator from 2002 to 2009 for candidates registered for Ph.D. in JNU

Coordinator of Tuberculosis and Microbial Infection in CDRI from 2009 onwards

Professional Society Involvement: (active membership in bold face)

       2004                            Chemical Research Society of India (CRSI), Life member

2003                            UP Science and Technology, Life member

2014                            Member of National Academy of Sciences, Allahabad

Ongoing/Completed Project Title:

a)         “Diversity Oriented Organic Synthesis of Small but Smart Molecules in Drug Discovery Research” of worth Rs. twenty lakhs, DST, New Delhi (2006-2009).

b)         Project Coordinator from CDRI on “Synthetic Biology (Metabolic Engineering of Vinca Alkaloid Pathway (Rs 81 lakhs) and Metabolic Engineering of Azadirachtin biosynthetic pathway (Rs 35 lakhs)” (2010-2013).

c)       “Design and Synthesis of Novel SERMs (Selective Estrogen Receptor Modulators) for the management of Osteoporosis and other estrogen related disorders” of Rs. seventeen lakhs, ICMR, New Delhi (2003-2006).

d)        “Design and Development of Tissue Selective Antiestrogens” of worth Rs. eleven lakhs, DST, New Delhi (2003- 2006).   

e)        “Amino Acids as chiral Synthons: Development of new synthetic protocols for creating Natural Products and related diversity in quest for anticancer agent” of Rs. 35 lakhs, DST, New Delhi (2010-2013).

f)       “Design, synthesis and evaluation of new chemical entities against atypical mycobacterium, Mycobacterium fortuitumof Rs. 40 lakhs, ICMR, New Delhi (2011-2013).             

g)        “Quest for Corannulene based Polyfunctional Molecules in Nanobiotechnology and Nanomedicine: Transporting and Translocating properties of Corannulene derived carrier systems” of Rs 53 lakhs, DST, New Delhi (2015-todate).

h)    Ligand and structure-based screening of designed and synthesized chemical library around Psammaplin A against DNA methyltransferase 1 (DNMT1) and Diversity oriented synthesis of Halimide & Phenylahistin related analogs as anticancer agents, of Rs 45 lakhs from MoES, New Delhi.

Group News:

Congrats Srinivas, Sudipta and Saroj for OBC paper on alkylideneoxindoles

Congrats for Tiash, Srinivas, Saurav and Bidhu for their paper in RSC Advances

Congrats Priyanka et al for their work on TB in SAR and QSAR in Environmental Research 

Welcome Manoj, Indranil and Deblina and Amit Kumar in the group

MoES project (GAP 0195) on DNMT has been approved

Alumni News:

Dr. Ritesh Singh (Ph.D. 2007-2012) has been awarded prestigious JSPS postdoctoral fellowship to work with Prof Takayoshi Suzuki, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, 606-0823, JAPAN

Dr. Ritesh Singh has been awarded prestigious DST Inspire faculty to work in IICT, Hyderabad

Dr. Sudipta Kumar Manna, (Ph.D. 2009-2014) has been awarded postdoctoral fellowship in Prof. Masato Kitamura’s group, University of Nagoya, Japan

Dr. Priyanka Singh, (Ph.D. 2009-2014) has been awarded postdoctoral fellowship to work with Professor Jean-Francois Hernandez, Institut des Biomolécules Max Mousseron, CNRS UMR5247, Faculté de Pharmacie, 34093 Montpellier cedex 5, France

Dr. Saurav Bera, (Ph.D. 2009-2014) has joined as research scientist in Dr. KPC life Sciences, Kolkata

Dr. Amit Kumar Jana, (Ph.D. 2009-2014) has joined as research chemist in TCG Life Sciences, Kolkata

For position of JRF/Project Assistant/Postdoc etc. contact me at gautam.panda@gmail.com; gautam_panda@cdri.res.in
For Postdoc fellowships one can also go through CSIR (http://www.csirhrdg.res.in/npdf.htm) or http://csirhrdg.res.in/ra.htm
/DBT (http://www.dbtindia.nic.in/funding-mechanism-2/fellowships-for-students), DST (http://www.serb.gov.in/npdf.php), http://www.inspire-dst.gov.in/faculty_scheme.html)
/ICMR (http://icmr.nic.in/jrf.htm) websites 



Comments