Uterine fibroids (singular Uterine Fibroma) are benign tumors which grow from the muscle layers of the uterus. They are the most common benign neoplasm in females. The symptoms depend on the size, location, number, and the pathological findings. Fibroids may be single or multiple. Most fibroids start in an intramural location, that is the layer of the muscle of the uterus. With further growth, some lesions may develop towards the outside of the uterus (subserosal or pedunculated), some towards the cavity (submucosal or intracavitary). Lesions affecting the cavity tend to bleed more and interfere with pregnancy. Secondary changes that may develop within fibroids are hemorrhage, necrosis, calcification, and cystic changes.
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