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References

Acid


[a-i] “I have observed that when the use of fat or oily food has been persevered in for some time, there is generally the presence of bile in the gastric fluids.” Experiments and Observations on the Gastric Juice, and the Physiology of Digestion by William Beaumont, 1833

Experiments and Observations on the Gastric Juice, and the Physiology of ... - William Beaumont, Alexis St. Martin - Google Books

https://books.google.co.uk/books?id=LOwqAAAAYAAJ&source=gbs_book_other_versions

[a-ii] Dramatic diurnal variation in the concentration of the human trefoil peptide TFF2 in gastric juice -- Semple et al. 48 (5): 648 -- Gut

http://gut.bmj.com/content/48/5/648.short

[a-iii] Host-Bacterial Interactions in Helicobacter pylori Infection - Gastroenterology

http://www.gastrojournal.org/article/S0016-5085(07)02016-1/abstract?

[a-iv] Results - Drug Class Review: Proton Pump Inhibitors - NCBI Bookshelf

http://www.ncbi.nlm.nih.gov/books/NBK47258/

[a-v] Systematic review of PPI and H2A in Reflux oesophagitis

http://www.medicine.ox.ac.uk/bandolier/bandopubs/gordf/gord.html

[a-vi] Esomeprazole provides improved acid control vs. omeprazole In patients with symptoms of gastro-oesophageal reflux disease. - PubMed - NCBI

http://www.ncbi.nlm.nih.gov/pubmed/10886041

[a-vii] Management of reflux esophagitis: does the choice of proton pump inhibitor matter? - PubMed - NCBI

http://www.ncbi.nlm.nih.gov/pubmed/25721889

[a-viii] BMC Gastroenterology | Full text | Gaviscon(R) vs. Omeprazole in symptomatic treatment of moderate gastroesophageal reflux. A direct comparative randomised tria...

http://www.biomedcentral.com/1471-230X/12/18

[a-ix] Proton pump inhibitor use may not prevent high-grade dysplasia and oesophageal adenocarcinoma in Barrett's oesophagus: a nationwide study of 9883 patients - PubMed ...

http://www.ncbi.nlm.nih.gov/pubmed/24617286

[a-x] Acid-suppressive medications and risk of oesophageal adenocarcinoma in patients with Barrett's oesophagus: a systematic review and meta-analysis -- Singh et al....

http://gut.bmj.com/content/early/2013/11/12/gutjnl-2013-305997

[a-xi] PPIs Protective for Esophageal Cancer

http://www.gastroendonews.com/ViewArticle.aspx?d=In+the+News&d_id=187&i=April+2014&i_id=1048&a_id=26309

[a-xii] Dyspepsia and gastro‑oesophageal reflux disease | 1-recommendations | Guidance and guidelines | NICE

http://www.nice.org.uk/guidance/cg184/chapter/1-recommendations#interventions-for-gastro-oesophageal-reflux-disease-gord-2

Bile


[b-i] Chronic diarrhea caused by idiopathic bile acid malabsorption: an explanation at last, Expert Review of Gastroenterology & Hepatology, Informa Healthcare

http://informahealthcare.com/doi/abs/10.1586/egh.09.49 

[b-ii] Acute Cholecystitis associated with pancreatic reflux

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1390992/

[b-iii] American Journal of Gastroenterology - Abstract of article: No association between gallstones and gastroesophageal reflux disease

http://www.nature.com/ajg/journal/v96/n10/abs/ajg2001715a.html


Reflux

[f-i]  Heller Myotomy Versus Heller Myotomy With Dor Fundoplication for Achalasia

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448931/

[f-ii]  Laparoscopic Nissen fundoplication in the treatment of Barrett's esophagus - 10 years of experience.

http://www.ncbi.nlm.nih.gov/pubmed/23837098

[f-iii]  20 years later: laparoscopic fundoplication durability.

http://www.ncbi.nlm.nih.gov/pubmed/25487547

[f-iv] Laparoscopic Nissen-Rossetti fundoplication is effective to control gastro-oesophageal and pharyngeal reflux 

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639973/

[f-v]  Laparoscopic Toupet versus Nissen fundoplication for the treatment of gastroesophageal reflux disease.

http://www.ncbi.nlm.nih.gov/pubmed/14717528

[f-vi]  Laparoscopic Nissen Fundoplication

http://emedicine.medscape.com/article/1892517-overview

[r-i] LPR - Aspiration of Upper Oesophageal Reflux (August 2014) 

https://sites.google.com/site/robichris/barretts/lpr

[r-ii] Heartburn Hell on the NBC Today Show: omitting things consumers might want to know about a $14K device - HealthNewsReview.org

http://www.healthnewsreview.org/2015/03/heartburn-hell-on-the-nbc-today-show-omitting-things-consumers-might-want-to-know-about-a-14k-device/

[r-iii] One Hundred Consecutive Patients Treated with Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease: 6 Years of Clinical Experience from a Single ...

http://www.journalacs.org/article/S1072-7515(13)00356-6/abstract

[r-iv] Device for acid reflux approved by FDA, but not by insurers - StarTribune.com

http://www.startribune.com/device-for-acid-reflux-approved-by-fda-but-not-by-insurers/303946711/

[r-v] LINX Procedure for GERD: Risks and Benefits

http://www.surgery.usc.edu/uppergi-general/gastroesophagealrefluxdisease-linx-risksbenefits.html

[r-vi] Laparoscopic insertion of a magnetic bead band for gastro-oesophageal reflux disease | Guidance and guidelines | NICE

http://www.nice.org.uk/guidance/ipg431

[r-vii] Long-term maintenance effect of radiofrequency energy delivery for refractory GERD: a decade later - Springer

http://link.springer.com/article/10.1007%2Fs00464-014-3461-6

[r-viii] Endoluminal Treatments for Gastroesophageal Reflux Disease (GERD) - A SAGES Guideline

http://www.sages.org/publications/guidelines/endoluminal-treatments-for-gastroesophageal-reflux-disease-gerd/

[r-ix] Antireflux Transoral Incisionless Fundoplication Using EsophyX: 12-Month Results of a Prospective Multicenter Study - Springer

http://link.springer.com/article/10.1007/s00268-008-9594-9/fulltext.html

[r-x] Two-year results of a feasibility study on antireflux transoral incisionless fundoplication using EsophyX - Springer

http://link.springer.com/article/10.1007/s00464-009-0384-8/fulltext.html

[r-xi] Clinical and pH-metric outcomes of transoral esophagogastric fundoplication for the treatment of gastroesophageal reflux disease - Springer

http://link.springer.com/article/10.1007/s00464-010-1497-9/fulltext.html

[r-xii] EsophyX for Transoral Incisionless Fundoplication (TIF) Proves Itself in Trial (w/video)

http://www.medgadget.com/2013/05/esophyx-for-transoral-incisionless-fundoplication-tif.html

[r-xiii] TIF Underperforming as Long-Term GERD Treatment

http://www.medscape.com/viewarticle/842806?src=wnl_edit_tpal&uac=121783PV

[r-xiv] Medigus Announces Completion of First Commercial Procedures in Turkey in GERD Patients Using New Generation of MUSE™ System

http://www.medigus.com/news-events/news/142-medigus-announces-completion-of-first-commercial-procedures-in-turkey-in-gerd-patients-using-new-generation-of-muse-system

[r-xv] First MUSE procedures for GERD performed in Italy

http://www.healio.com/gastroenterology/therapeutics-diagnostics/news/online/%7Ba24031e8-ad19-4194-a529-9e64d20ea82b%7D/first-muse-procedures-for-gerd-performed-in-italy

[r-xvi] Endoscopic anterior fundoplication with the Medigus Ultrasonic Surgical Endostapler (MUSE™) for gastroesophageal reflux disease: 6-month results from a multi-center prospective trial

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293474/

[r-xvii] Endoluminal gastroplication for gastro-oesophageal reflux disease | 1-guidance | Guidance and guidelines | NICE

http://www.nice.org.uk/guidance/IPG404/chapter/1-guidance

[r-xviii] Endocinch therapy for gastro-oesophageal reflux disease: a one year prospective follow up

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1773510/

[r-xviv] Long term failure of endoscopic gastroplication (EndoCinch)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774515/

[r-xx] EndoCinch Procedure: Success Rates

http://www.healthline.com/health/gerd/endocinch-procedure#2

[r-xxi] StomaphyX Gastric Bypass Revision Surgery

http://bariatric.stopobesityforlife.com/obesity-surgery/correcting-obesity/procedures/stomaphyx/

[r-xxii] Short-term electrical stimulation of the lower esophageal sphincter increases sphincter pressure in patients with gastroesophageal reflux disease

http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2012.01878.x/full

[r-xxiii] Electrical stimulation therapy of the lower esophageal sphincter is successful in treating GERD: final results of open-label prospective trial - Springer

http://link.springer.com/article/10.1007/s00464-012-2561-4/fulltext.html

[r-xxiv] EndoStim Treats First Patient with Severe Acid Reflux... -- THE HAGUE, Netherlands and ST. LOUIS, Feb. 19, 2013 /PRNewswire/ --

http://www.prnewswire.com/news-releases/endostim-treats-first-patient-with-severe-acid-reflux-in-germany-with-endostim-les-stimulation-system-191921281.html

[r-xxv] Long-term results of electrical stimulation of the lower esophageal sphincter for the treatment of gastroesophageal reflux disease

https://www.thieme-connect.com/DOI/DOI?10.1055/s-0033-1344213

[r-xxvi] Two-year results of intermittent electrical stimulation of the lower esophageal sphincter treatment of gastroesophageal reflux disease - Surgery

http://www.surgjournal.com/article/S0039-6060(14)00708-9/fulltext

[r-xxvii] EndoStim Launches Second Generation Neurostimulation Device for GERD -- NIJMEGEN, Netherlands and ST. LOUIS, May 18, 2015 /PRNewswire/ --

http://www.prnewswire.com/news-releases/endostim-launches-second-generation-neurostimulation-device-for-gerd-300084689.html

[r-xxviii] Endoluminal gastroplication for gastro-oesophageal reflux disease

http://www.nice.org.uk/guidance/ipg404

[r-xxviv] Electrical stimulation of the lower oesophageal sphincter for treating gastro-oesophageal reflux disease | Guidance and guidelines | NICE

http://www.nice.org.uk/guidance/indevelopment/gid-ip1244

[r-xxx] Endoscopic implantation of enteryx for treatment of GERD: 12-month results of a prospective, multicenter trial. - PubMed - NCBI

http://www.ncbi.nlm.nih.gov/pubmed/14499767

[r-xxxi] Enteryx implantation for GERD: expanded multicenter trial results and interim postapproval follow-up to 24 months

http://www.rima.org/web/medline_pdf/GastrointestEndosc_650-8.pdf

[r-xxxii] Complications involving the mediastinum after injection of Enteryx for GERD - Gastrointestinal Endoscopy

http://www.giejournal.org/article/S0016-5107(04)02645-8/abstract

[r-xxxiii] Public Health Notifications (Medical Devices) > FDA Preliminary Public Health Notification*: Recall of Boston Scientific ENTERYX® Procedure Kits.

http://www.fda.gov/MedicalDevices/Safety/AlertsandNotices/PublicHealthNotifications/ucm064523.htm

[r-xxxiv] Visceral artery embolization after endoscopic injection of Enteryx for gastroesophageal reflux disease

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242123/

[r-xxxv] Endoscopic augmentation of the lower oesophageal sphincter using hydrogel implants for the treatment of gastro-oesophageal reflux disease

http://www.nice.org.uk/guidance/IPG222/chapter/1-guidance

[r-xxxvi] A now rarely seen anti-reflux device: The Angelchik prosthesis - International Journal of Case Reports and Images (IJCRI)

http://www.ijcasereportsandimages.com/archive/2013/007-2013-ijcri/015-07-2013-sloane/ijcri-015072013115-sloane-full-text.php

[r-xxxvii] Dysphagia Secondary to an Angelchik Prosthesis Insertion: the Role of Laparoscopic Management - SAGES Abstract Archives

http://www.sages.org/meetings/annual-meeting/abstracts-archive/dysphagia-secondary-to-an-angelchik-prosthesis-insertion-the-role-of-laparoscopic-management/

[r-xxxviii] Complications of the Angelchik Antireflux Prosthesis | Annals of Internal Medicine

http://annals.org/article.aspx?articleid=698225

[r-xxxix]
Efficacy of a Novel “UES Assist Device” in Management of Supraesophageal Complications of Reflux Disease: the Results of a Limited Clinical Trial

http://www.gastrojournal.org/article/S0016-5085(12)60385-0/pdf

[r-xl] Use of a Sleep Positioning Device Significantly Improves Nocturnal Gastroesophageal Reflux Symptoms

http://medcline.com/wp-content/uploads/2015/04/Gabbard-et-al.-Use-of-a-Sleep-Positioning-Device-Significantly-Improves-Nocturnal-Gastroesophageal-Reflux-Symptoms.pdf

[r-xli] A Novel Sleep Assist Device Prevents Gastroesophageal Reflux: A Randomized Controlled Trial

http://medcline.com/wp-content/uploads/2015/04/Person-et-al.-A-Novel-Sleep-Device-Prevents-Gastroesophageal-Reflux.pdf

[r-xlii] Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

http://clincancerres.aacrjournals.org/content/14/14/4491.full

[r-xliii] Japanese apricot improves symptoms of gastrointestinal dysmotility associated with gastroesophageal reflux disease.

http://www.ncbi.nlm.nih.gov/pubmed/26185391

Complications


[c-i] UK tops WHO gullet cancer table and obesity may be factor - BBC News

http://www.bbc.co.uk/news/health-29634263

[c-ii] Long-term Consequences of Chronic Proton Pump Inhibitor Use


[c-iii] Consumer Use of Over-the-Counter PPIs in Patients With GERD


[c-iv] Proton pump inhibitor use and the risk of small intestinal bacterial overgrowth: a meta-analysis. - PubMed - NCBI


Tests and diagnosis


[t-i] Systematic Four-Quadrant Biopsy Detects Barrett's Dysplasia

http://www.medscape.com/viewarticle/572642

[t-ii] The Seattle protocol does not more reliably predict the detection of cancer at the time of esophagectomy than a less intensive surveillance protocol. - PubMed -...

http://www.ncbi.nlm.nih.gov/pubmed/19264576

[t-iii] Diagnosis of extraesophageal reflux in children with chronic otitis media with effusion using Peptest.


[t-iv] Gastroenterology & Endoscopy News - U.K. Study Finds No Need for Diagnostic Barium Test


Treatments

[tr-i] New British Society of Gastroenterology (BSG) guidelines for the diagnosis and management of Barrett's oesophagus


[tr-ii] Radiofrequency Ablation in Barrett's Esophagus with Dysplasia — NEJM


[tr-iii] Comparing outcome of radiofrequency ablation in Barrett's with high grade dysplasia and intramucosal carcinoma: a prospective multicenter UK registry... - Abstract - Europe PubMed Central


[tr-iv] Cryotherapy for Barrett's esophagus and esophageal cancer. - PubMed - NCBI


[tr-v] Horizon Scanning in Surgery: Application to Surgical Education and Practice - Cryotherapy for Esophageal Cancer


[tr-iv] Photodynamic therapy vs radiofrequency ablation for Barrett’s dysplasia: Efficacy, safety and cost-comparison


[tr-vii] Randomized trial of argon plasma coagulation vs. multipolar electrocoagulation for ablation of Barrett's esophagus.


[tr-viii] A prospective comparison of totally minimally invasive versus open Ivor Lewis esophagectomy


Other

[o-i] The effects of concomitant GERD, dyspepsia, and rhinosinusitis on asthma symptoms


[o-ii] Gastroesophageal reflux as a cause of chronic cough, severe asthma, and migratory pulmonary infiltrates


[o-iii] Chronic Asthma and Gastro-Esophageal Reflux Disease: The Treatment Plans


[o-iv] CORE Dumping Syndrome factsheet


[o-v] Closer to a treatment for the 'asthma of the esophagus' | EurekAlert! Science News



Myths and Misconceptions


[m-i] Negative Effects of Alkaline Water | eHow

http://www.ehow.com/list_7609516_negative-effects-alkaline-water.html

[m-ii] What You Need to Know When You Prescribe a PPI: Cancer

http://www.medscape.com/viewarticle/753221_5

[m-iii] Don’t believe the hype – 10 persistent cancer myths debunked - Cancer Research UK - Science blog