BIOINFORMATICS‎ > ‎FACULTY‎ > ‎

Dr. M. JAYAKANTHAN



                                                                                          
PUBLICATIONS



2017

  • Vaithinathan S Sumanth CS,  Mahesh T, Jayakanthan M, Jocelyn LC & Premendu PM, Alexander P, Juan AS, David WM and Nilanjana M (2017). Regulation of A-Kinase-Anchoring Protein 12 by Heat Shock Protein A12B to Prevent Ventricular Dysfunction Following Acute Myocardial Infarction in Diabetic Rats. Journal of Cardiovascular Translational Research (Published by Springer) 10(2):209-220



2016

  • Keerthana P, Gnanam R, Uma D, Jayakanthan M, Rajamani K and Jayadeepa RM (2016). Polyketide Natural Products, Acetogenins from Graviola (Annona muricata L), its Biochemical, Cytotoxic Activity and Various Analyses through Computational and Bio-Programming Methods. Current Pharmaceutical Design (Published by Bentham Science) 22(34):5204-5210.
 



2014

  • Pranitha J, Jayakanthan M and Mathur PP (2014). Structural analysis of MARK4 and exploration of specific inhibitors for MARK family: A computational approach to obstruct the role of MARK4 in Prostate Cancer progression. Molecular BioSystems (Published by Royal Society of Chemistry, Cambridge) 10(7): 1845-1868.

  • Jayakanthan M, Pranitha J and Mathur PP (2014). Computational analysis of CYP3A4 mediated metabolism to investigate drug interactions between anti-TB and anti-HIV drugs in HIV/TB co-infection. Medicinal Chemistry Research (Published by Springer) 23(2):905–917.

 
 

2012
  • D'Cruz SC, Jubendradass R, Jayakanthan M, Rani SJ and Mathur PP (2012). Bisphenol A impairs insulin signaling and glucose homeostasis and decreases steroidogenesis in rat testis: An in vivo and in silico study. Food and Chemical Toxicology (Published by Elsevier) 50(3-4):1124-1133.  
 















2011
  • Muthukumaran J, Jayakanthan M, Chandrasekar S and Mathur PP (2011). Bind-Predict: An algorithm for identifying zinc finger binding motifs in DNA sequences. Journal of Computational Biology and Bioinformatics Research (Published by Academic Journals) 3(7):91-102.
  • Cheng CY, Lie PP, Mok KW, Cheng YH, Wong EW, Jayakanthan M, Mathur PP, Yan HH and Mruk DD (2011). Interactions of laminin β3 fragment with β1-integrin receptor: A revisit of the apical ES-BTB-hemidesmosome functional axis in the testis. Spermatogenesis (Published by Landes Bioscience) 1(3):174-185.
  • Jayakanthan M, Pranitha J and Mathur PP (2011). A Computational Study of CYP3A4 Mediated Drug Interaction Profiles for Anti-HIV Drugs. Journal of Molecular Modeling (Published by Springer) 17 (8):1847-1854. 
  • Cheng CY, Wong EW, Lie PP, Li MM, Mruk DD, Yan HH, Mok KW, Jayakanthan M, Mathur PP, Lui WY, Lee WM, Bonanomi M and Silvestrini B (2011). Regulation of blood-testis barrier dynamics by desmosome, gap junction, hemidesmosome and polarity proteins: An unexpected turn of events. Spermatogenesis (Published by Landes Bioscience) 1(2):105-115. 
  • Cheng CY, Wong EW, Lie PP, Li MW, Su L, Siu ER, Yan HH, Jayakanthan M, Mathur PP, Bonanomi M, Silvestrini B, and Mruk DD (2011). Environmental toxicants and male reproductive function. Spermatogenesis (Published by Landes Bioscience) 1(1):02-13. 





2010
  • Punetha A, Muthukumaran J, Hemron A J, Arumugam N, Jayakanthan M and Sundar D (2010). Towards understanding the regulation of rubber biosynthesis: insights in to the initiator and elongator enzymes. Journal of Bioinformatics and Sequence Analysis (Published by Academic Journals) 2(1):001-010.
  • Jayakanthan M, Chandrasekar S, Muthukumaran J and Mathur PP (2010). Analysis of CYP3A4-HIV-1 Protease drugs interactions by computational methods for Highly Active Antiretroviral Therapy in HIV/AIDS. Journal Molecular Graphics and Modelling (Published by Elsevier) 28 (5):455-463. 
 












2009
  • Chakradhara Rao SU, Anichavezhi D, Muthukumaran J, Jayakanthan M, Mathur PP, Shewade GD, Krishnamoorthy R and Adithan C (2009). Influence of the genetic polymorphisms in the 5' flanking and exonic regions of CYP2C19 on proguanil oxidation. Drug Metabolism and Pharmacokinetics (Published by the Japanese Society for the Study of Xenobiotics) 24 (6):537-548. 
  • Jayakanthan M, Muthukumaran J, Chandrasekar S, Chawla K, Punetha A and Sundar D (2009). ZifBASE: a database of zinc finger proteins and associated resources. BMC Genomics (Published by BioMed Central) 10:421. 
  • Balachandran N, Kichenamourthy S, Muthukumaran J, Jayakanthan M, Chandrasekar S, Punetha A and Sundar D (2009). Diversity of true mangroves and their associates in the Pondicherry region of South India and development of a mangrove knowledgebase. Journal Ecology and the Natural Environment (Published by Academic Journals) 1(5):99-105.
  • Prabhakaran S, Srividya V, Bharathi N, Jayakanthan M and Manikanda Boopathi N (2009). Use of computational and structural Bioinformatic strategies in controlling Fusarium wilt in cotton. Online Journal of Bioinformatics (Published by OJB) 10(2):180-190.
  • Jayakanthan M, Wadhwa G, Mohan TM, Arul L, Balasubramanian P and Sundar D (2009). Computer-Aided Drug Design for Cancer-Causing H-Ras p(21) Mutant Protein. Letters in Drug Design and Discovery (Published by Bentham Science) 6(1):     14-20.

 
2008
  • Gowthaman U, Jayakanthan M and Sundar D (2008). Molecular docking studies of dithionitrobenzoic acid and its related compounds to protein disulfide isomerase: computational screening of inhibitors to HIV-1 entry. BMC Bioinformatics (Published by BioMed Central) 9 (Suppl 12):S14.

BOOK CHAPTERS


2018

  • Peter, S.C., Dhanjal, J.K., Malik, V., Radhakrishnan, N., Jayakanthan, M. and Sundar, D. (2018). Quantitative structure-activity relationship (QSAR): modeling approaches to biological applications. In: Encyclopedia on Bioinformatics and Computational Biology, Ranganathan, S., Nakai, K., Gribskov, M. and Schonbach, C. (Eds.), pp. 661-676, Elsevier, UK (Book ISBN: 978-0-128-11414-8)


2018
  • Jayakanthan M and Mathur PP (2018). Role of Bioinformatics in Drug Resistance Prediction for HIV/AIDS. In: Current Trends in Bioinformatics: An Insight Methods in Molecular Biology (Proteome Bioinformatics), G. Wadhwa et al. (Eds). p. 1549: 277-286. Springer Nature Singapore Pte Ltd. (ISBN 978-981-10-7481-3)


2017
  •  Swathik Clarancia P, Jayakanthan M, and Mathur PP (2017). In Silico Approach to Identify Potential Inhibitors for Axl-Gas6 Signaling. In: Methods in Molecular Biolog(Proteome Bioinformatics), Shivakumar K and Suresh M. (Eds) p. 1549: 221-229, Springer Protocols, Springer New York. (ISBN 978-1-4939-6738-4)


2015

  • Jayakanthan M, Jubendradass R, D'Cruz SC, Mathur PP (2015). A use of homology modeling and molecular docking methods: to explore binding mechanisms of nonylphenol and bisphenol A with antioxidant enzymes. In: Methods in Molecular Biology (Computational Peptidology), Zhou P and Huang J. (Eds) p.1268:273-289, Humana Press. (ISBN 978-1-4939-2285-7) 
 

2014

  • Xiao X, Mruk DD, Pranitha J, Jayakanthan M, Mathur PP, Lee WM, Silvestrini B, Cheng YH, and Cheng CY (2013). Nonreceptor Protein Kinases c-Src, c-Yes, and FAK Are Biomarkers for Male Contraceptive Research. In: New Advances on Disease Biomarkers and Molecular Targets in Biomedicine, Lee, Nikki P.; Cheng, C.Y.; Luk, John M. (Eds.) p.1-25, Humana Press. (ISBN 978-1-62703-455-5)


2012

  • Mok KW, Lie PP, Mruk DD, Jayakanthan M, Mathur PP, Silvestrini B and Cheng CY (2012). The apical ectoplasmic specialization-blood-testis barrier functional axis is a novel target for male reproduction. In: Biology and Regulation of Blood-Tissue Barriers, C.Y. Cheng (Ed.) p.334-355, Landes Bioscience and Springer Science+Business Media. (ISBN: 978-1-4614-4710-8)
  

                                                                                                 PROJECTS        

On-Going Projects Details:
 
 S. No Project Name  Funding Agency  Date of Completion Budget

1
Genome and transcriptome sequencing of aromatic rices from North Eastern region under DBT’s program for the NE (CO-PI)
 DBT

 2019

25.48 lakhs   

2
Whole genome and transcriptome study of stress-tolerant banana cultivars (CO-PI)
 DBT

 2020

43 lakhs