The simplest version simply dispenses an allotted volume of liquid from a motorized pipette or syringe; more complicated machines can also manipulate the position of the dispensers and containers and/or integrate additional laboratory devices, such as centrifuges, microplate readers, heat sealers, heater/shakers, bar code readers, spectrophotometric devices, storage devices and incubators.They can range from a specialized bench-top 8-channel DNA PCR processing robot, to a customized-for-process automated liquid handling system. Other liquid handling systems are specifically designed for specific experiments, e.g. the Intavis InsituPro robot for the automation of immunohistochemistry and in situ hybridization on whole-mounts and slides.