Amos was born on April 16, 1923 in Bromely, Kent, England. He loved to experiment with chemicals. He attended Sir John Cass Technical Institute. In 1947 he received his M.B. Degree from Chelsea Polytechnic. Soon after, he enrolled at Guy's Medical School where he earned a B.S. degree in 1951 and a Postgraduate M.D. degree in 1963 (Arnold, 2010).
One of Amos's greatest contributions to the world of biotechnology was his work in allotransplantation-"the transplantation of cells, tissues, and organs from a genetically non-identical member of the same species"-leading to the first ever kidney transplant. Amos was the first to recognize how studying different ethnic populations could help to understand the way Major Histocompatibility complex's were evolved. His work on the "genetics of individuality" provided the world a better idea of how immunity works. These ideas have grown in the years since Amos discovered them. Technology used to help transplant has only evolved and the surgeries have become more standard and much less dangerous.
In 1962 Amos was approched by Duke University to be a professor of experimental surgery. He spent over forty years at Duke researching immunogenetics, tumor immunity, and transplantation immunology (Tedder, 2003). His work was so beneficial in the field he University put together the Bernard Amos Fellowship, funding graduate students training in Immunology. Amos founded the International Transplantation Society. He also co-founded and was Editor-in-Chief of the Journal, Human Immunology.