Research Interests

I am a Ph.D. student in Organismic and Evolutionary Biology at Harvard University in the lab of Michael Desai. I use theory and experimental evolution to study the statistical properties of adaptation. I also develop bioinformatic methods for analyzing whole genome sequence data. As an undergraduate at Yale, I worked with Jeff Townsend to develop tests for selection on quantitative traits.

Publications

Hodgins-Davis, A., Rice, D.P., & Townsend, J.P.. (2015Gene expression evolves under a House-of-Cards model of stabilizing selection. Molecular Biology and Evolution.

Rice, D. P., Good, B. H., and Desai, M. M. (2015). The evolutionarily stable distribution of fitness effects. Genetics.

Herman, J. D., Rice, D. P.,  et al(2014). A Genomic and Evolutionary Approach Reveals Non-Genetic Drug Resistance in Malaria. Genome Biology 15(11): 511.

Kryazhimskiy, S.*, Rice, D. P.*, Jerison, E., & Desai, M. M. (2014). Global epistasis makes adaptation predictable despite sequence-Level stochasticity. Sciencedoi:http://dx.doi.org/10.1101/001784

Lang, G. I.*, Rice, D. P.*, Hickman, M. J., Sodergren, E., Weinstock, G. M., Botstein, D., & Desai, M. M.    (2013). Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations. Nature, 500(7464), 571-574. doi:10.1038/nature12344

Rice, D. P., & Townsend, J. P. (2012). Resampling QTL Effects in the QTL sign test leads to incongruous sensitivity to variance in effect size. G3, 2(8), 905-911. doi:10.1534/g3.112.003228

Rice, D. P., & Townsend, J. P. (2012). A test for selection employing quantitative trait locus and mutation accumulation data. Genetics, 190(4), 1533-1545. doi:10.1534/genetics.111.137075

Kryazhimskiy, S., Rice, D. P., & Desai, M. M. (2012). Population subdivision and adaptation in asexual populations of Saccharomyces cerevisiae. Evolution, 66(6), 1931-1941. doi:10.1111/j.1558-5646.2011.01569.x

*contributed equally