I will give a short course on Memory-Centric Computing for the Generative AI Era at IEEE IEDM, San Francisco, on Dec. 13, 2026
New work: An Ising machine combining memristors and magnetic tunnel junctions with intrinsic annealing. Nature Communications (2026)
Perspective: How Bayesian electronics can enable trustworthy AI Nature Reviews Electrical Engineering (2025)
New work: BiMU enables efficient, continual learning with metaplastic binary Bayesian neural networks. ICML (2026).
New work: MESU uses Bayesian uncertainty to balance learning and forgetting. Nature Communications (2025).
New work: A hybrid ferroelectric–memristor memory enables both learning and inference. Nature Electronics (2025).
New work: the memristor-based self-powered neural network harvests its energy and adjusts its accuracy depending on available energy. Nature Communications (2024)
New work: a memristor-based Bayesian neural network can recognize arrhythmia with uncertainty evaluation. Nature Communications (2023)
New work: our Bayesian machine has been published in Nature Electronics (2023). This work was covered by Nature and IEEE Spectrum
Damien Querlioz is a CNRS Research Director at the Centre de Nanosciences et de Nanotechnologies of Université Paris-Saclay and CNRS. He was first trained at Ecole Normale Supérieure Paris as a physicist and at Ecole Supérieure d'Electricité as a microelectronics engineer. He received the Ph.D. degree from Université Paris-Sud in 2009. He was then a Postdoctoral Scholar at Stanford University and at the Commissariat a l'Energie Atomique.
Damien Querlioz develops new concepts in nanoelectronics relying on bio-inspiration. He believes that nanoelectronics can allow inventing highly energy-efficient forms of memory-centric computing. He investigates stochastic approaches, the use of spintronics devices for bioinspired systems, and the connection between bioinspired memories and Bayesian inference. His research interests have also included the physics of advanced nanodevices. He has developed the Wigner Monte Carlo approach to simulate and understand quantum transport in nanometer-scale devices.
In 2016, Damien Querlioz received the Habilitation degree (HDR). In 2017, he cofounded the interdisciplinary INTEGNANO research group, with amazing colleagues working around an integrative and multidisciplinary approach to the development of novel charge and spin-based devices, which he led until in 2023. He works with fantastic students and postdocs.
Damien Querlioz has coauthored 9 book chapters, more than 150 journal articles and conference proceedings and given more than 100 invited talks at national and international workshops and conferences. He has also coauthored the book "The Wigner Monte-Carlo Method for Nanoelectronic Devices" (London: ISTE; Hoboken: Wiley, 2010) with Philippe Dollfus. In 2017, he received a CNRS Bronze medal. He has also been a co-recipient of the 2017 IEEE Guillemin-Cauer Best Paper Award and of the 2018 IEEE Biomedical Circuits and Systems Best Paper Award.
The research of Damien Querlioz has been funded by the European Research Council, the Seventh Framework Programme of the European Union, Horizon 2020, Horizon Europe, Agence Nationale de la Recherche, Région Ile-de-France/DIM NANO-K and Ministère de l'écologie, du développement durable et de l'énergie. Starting 2022, he has been leading the BioElectronPhoton project of PEPR Electronique.
Artificial Intelligence is transforming computing, but its remarkable progress comes with growing demands for energy and memory. A major part of this challenge comes not just from computation itself, but from storing, moving and updating information.
My research explores how emerging nanotechnologies can make AI more energy-efficient by fundamentally rethinking the relationship between memory, computation and learning.
The brain provides a fascinating source of inspiration. Unlike conventional computers, it tightly integrates memory and computation, and exploits the complex, sometimes stochastic behavior of its basic components. My research builds on two ideas inspired by these observations.
1. Bringing memory and computation together
Emerging nanotechnologies offer exciting opportunities in this direction. Devices such as memristors, ferroelectric memories, and magnetic memories can store information in extremely compact structures, and sometimes participate directly in computation.
Together with my students and collaborators, I investigate how to combine these technologies with conventional electronics to build new computing architectures. Our work ranges from neural networks to Bayesian inference, including experimental demonstrations of hybrid memories that support both learning and inference.
Today, this challenge extends beyond storing neural network weights: modern generative AI also needs to manage information that changes continuously as it processes new inputs. This opens fascinating opportunities for new types of memory-centric computing.
2. Exploiting the physics of nanodevices
Conventional computers are designed to perform highly accurate, deterministic operations. To achieve this, they carefully suppress much of the complexity of their underlying devices. But what if the physical properties that make nanodevices imperfect for conventional computing could become useful for AI?
Emerging memories exhibit rich behaviors, including stochastic switching, nonlinear dynamics, and varying degrees of information retention. Instead of eliminating these effects, we explore how to exploit them for computation.
This approach has led us to develop Bayesian machines that compute with probabilities and uncertainty, Ising machines that exploit physical randomness for optimization, and learning algorithms that adapt continuously without forgetting everything they previously learned.
A recurring theme is Bayesian electronics: combining probabilistic algorithms with emerging devices to build AI systems that can evaluate their uncertainty and learn from limited data. See our perspective in Nature Reviews Electrical Engineering.
All this work is highly interdisciplinary and can only happen within a context of strong collaboration, and I am happy to work with an ensemble of fantastic collaborators!
Recent external collaborations: Julie Grollier at the CNRS/Thales lab (Palaiseau), Fabien Alibart at IEMN (Lille), Jacques Droulez and Pierre Bessière at ISIR (Paris), Emmanuel Mazer at LIG (Grenoble), Raphael Laurent at La Poste/ProBAYES (Grenoble), Elisa Vianello and Etienne Nowak at LETI (Grenoble), Jean-Michel Portal and Marc Bocquet at IM2NP (Marseille), Sandip Tiwari at Cornell University (USA), Manan Suri at IIT Delhi (India), Omid Kavehei at the University of Sydney (Australia), Jayasimha Atulasimha at Virginia Commonwealth University (USA).
Email: damien.querlioz@c2n.upsaclay.fr
Office Phone: (+33)170270403
Postal Address: Damien Querlioz, Centre de Nanosciences et de Nanotechnologies, 10 Boulevard Thomas Gobert, 91120 Palaiseau, France
I am part of the the interdisciplinary INTEGNANO research group at C2N.
I love to have visitors in the lab! Do not hesitate to contact if you would like to visit. Here are some former visitors.
ERC Starting Grant NANOINFER (2017-2022).
Coordinated by Julie Grollier. I represent the C2N partner.
The project investigates neuromorphic computation with spin ice
Coordinated by Julie Grollier. I represent the C2N partner.
The project investigates alternative model of computations using spin oscillators. With UMR CNRS/Thales, IEF/NOMADE and CEA/DSM.
Ministère de l'écologie, du développement durable et de l'énergie (2016-2018).
Coordinated by Damien Querlioz. Project "S'inspirer de la nature : une solution pour inventer des systèmes plus efficaces énergétiquement". Covers all the research costs of PhD student D. Vodenicarevic, and organization of a workshop with doctoral school EOBE, Univ. Paris-Saclay.
ANR JCJC CogniSpin (2013-2016) (young researcher grant).
Coordinated by Damien Querlioz. We used magnetic memory as nanosynapses. The project covered the device as well as the circuits and systems implications of this idea.
Région Ile-de-France / DIM NANO-K StochaChips (2013-2016).
Funded the PhD of Alice Mizrahi (joint PhD between UMR CNRS/Thales and IEF).
FP7 FETOPEN Bottom-up Approaches to Machines dedicated to Bayesian Inference (BAMBI 2014-2016)
Coordinated by Jacques Droulez at ISIR∕UPMC. I represent the IEF partner.
We proposed a theory and a hardware implementation of probabilistic computation inspired by biochemical cell signalling. We studied probabilistic computation following three axes: algebra, biology, and hardware.
With different CNRS labs (ISIR, UMR CNRS/Thales, LIG), Instituto de Sistemas e Robotica-Associacao (Portugal), the Hebrew University of Jerusalem (Israel), ProBayes SAS (France), Universite de Liege (Belgium).
CNRS/MI DEFIBAYES (2013 - 2014).
Coordinated by Damien Querlioz. We aimed at understanding how to design a Bayesian accelerator, from the nanotechnology to its macrosopic application. We focused specifically on the transition between levels from the ato- to the macro- scale (nanotechnology, circuit, architecture, programming, application). With UMR CNRS/Thales, TIMA, LPPA/ISIR, LIG. This project led to the FP7 FETOPEN BAMBI grant.
CNRS/MI Probabilistic Computing (2012).
Coordinated by Julie Grollier. With UMR CNRS/Thales, LPPA/ISIR, LIG. We discovered how spintronics could allow a novel form of Bayesian computing (BAMBI and DEFIBAYES projects).
CNRS/INSIS PEPS Stochastic Synapses (2011-2012).
Coordinated by Damien Querlioz. With UMR CNRS/Thales, IM2NP, CEA/DACLE. We discovered how nanosynapses used in a stochastic way could allow low-power cognitive-types problems..