SCORE - CRVO & BRVO Notes

 
Visual Acuity

 

This chart shows the change in visual acuity at 1 year for the group that was given no drug (sham) and the group that was given the lower dose of triamcinolone acetonide. Blue represent improvements in visual acuity. Purple represent declines in visual acuity. Orange represents stability.

 

Cataract
The chart on the left shows the rate of cataract onset or progression from the SCORE-CRVO study and also from the SCORE-BRVO study. The chart on the right shows the rate of cataract surgery within two years. Both of these charts display rates which only include data from those in the study who still had their natural lens (phakic).
 
Intraocular Pressure
The chart on the left shows the rate at which people started eye pressure lowering medications during the first year of the studies. The chart on the rights shows the number of glaucoma procedures as a percentage of those who were initially assigned to the respective groups. However a substantial number of the procedures were determined to be necessary because of neovascular glaucoma as opposed to the effect of IVTA on intraocular pressure.1
 
Neovascular Complications
Neovascular complications occurred in all groups in both the CRVO and BRVO studies.
 

References & Resources

1 - Ip MS, Scott IU, VanVeldhuisen PC, Oden NL, Blodi BA, Fisher M, Singerman LJ, Tolentino M, Chan CK, Gonzalez VH; SCORE Study Research Group. A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with observation to treat vision loss associated with macular edema secondary to central retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 5. Arch Ophthalmol. 2009 Sep;127(9):1101-14. [PubMed]  [Free Full Text]

2 - Scott IU, Ip MS, VanVeldhuisen PC, Oden NL, Blodi BA, Fisher M, Chan CK, Gonzalez VH, Singerman LJ, Tolentino M; SCORE Study Research Group. A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with standard care to treat vision loss associated with macular Edema secondary to branch retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 6. Arch Ophthalmol. 2009 Sep;127(9):1115-28. [PubMed]  [Free Full Text]

Disclaimer: Since I am only a fellow patient and have no medical background you should not base any of your medical decisions on these notes or videos. Seek the advice of a competent medical professional promptly before making medical decisions.

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