News from the Stein Lab


PhD student Margaret DeMaegd wins University Scholarship

posted Dec 6, 2019, 3:42 PM by Wolfgang Stein

Congrats to PhD student Margaret DeMaegd for being awarded the Robert Preston University Club Scholarship. The photo shows Maggie with Dr. Preston as she receives her award. 

BSSA Research Symposium

posted Nov 20, 2019, 9:32 PM by Wolfgang Stein   [ updated Nov 20, 2019, 9:34 PM ]

Proud of Saisu Talasu, High school student in the lab, and Maisam Yousef, undergraduate student, for presenting their research at the annual BSSA Research Symposium today. 
Maisam won 2nd place in the oral presentation competition. Congrats!

Saisu presenting her poster.


Maisam at the rig.

MS student Josselyn Gonzalez speaking at the Charles Morris STEM Social for underrepresented students

posted Nov 19, 2019, 9:35 AM by Wolfgang Stein

Josselyn volunteered at the 6th annual Charles Morris STEM Social for underrepresented students as a representative of the Louis Stokes Alliances for Minority Participation (LSAMP). Josselyn talked about student opportunities and the LSAMP/STEMAlliance, and the services and support the program offers to underrepresented students.


Calcium imaging video

posted Nov 7, 2019, 11:00 PM by Wolfgang Stein   [ updated Nov 7, 2019, 11:01 PM ]

Finally a new video on our youtube channel. Calcium imaging of pacemaker neuropil activity in the stomatogastric ganglion. 

https://www.youtube.com/watch?v=fAqkxm8rD8k

YouTube Video



PhD student Margaret DeMaegd at the Neural Systems and Behavior Course

posted Nov 7, 2019, 10:53 PM by Wolfgang Stein

Margaret DeMaegd, PhD student in our lab, participated in this year's Neural Systems and Behavior Course. Our ISU news site had us featured: 



Phi Sigma Research Symposium

posted Apr 13, 2019, 10:15 AM by Wolfgang Stein   [ updated Apr 13, 2019, 10:16 AM ]

Congrats to everyone in the lab for another successful Phi Sigma Research Symposium and great presentations!

Special shout-out to our three prize winners Josselyn Gonzalez (best oral presentation), Maisam Yousef (third place undergraduate poster), and Margaret DeMaegd (best graduate poster).


The lab at the Symposium

Undergraduate researcher Maisam Yousef explaining her poster.

Our three winners: Margaret Demaegd, Maisam Yousef, Josselyn Gonzalez.



University Research Symposium

posted Apr 5, 2019, 4:12 PM by Wolfgang Stein

Our students presented at this year's University research symposium. With four posters from graduate students and one undergraduate poster we were among the most productive labs. The photos below show undergraduate student Maisam Yousef presenting her poster on how backpropagating action potentials influence sensory encoding, and PhD student Margaret DeMaegd and her poster on temperature responses in the nervous system.



ScienceTrend article about our PloS Biology paper

posted Mar 19, 2019, 10:52 AM by Wolfgang Stein

Great article on ScienceTrend about our @PLOSBiology paper on how multisensory information is encoded in the nervous system: http://buff.ly/2HGN4ga




Confocal imaging of pyloric axons with distinct properties

posted Dec 27, 2018, 10:07 AM by Wolfgang Stein   [ updated Dec 27, 2018, 11:04 AM ]

Our lab is interested in temperature effects on neurons and their function. Most long distance communication in the nervous system is carried our by long neuronal processes called axons. These thin "wires" have distinct properties that remain poorly understood. We are testing how a temperature increase (for example during a fever) affects neuronal information as it travels along axons. As a first step, we need to describe the different properties of the axons, and one of the them is their thickness and fine structure.

Video 1 below shows a 3D rendering of the axons of the three main motor neurons in the pyloric central pattern generator in the stomatogastric ganglion of the crab, Cancer borealis. More than 100 individual iImages were taken with a Nikon confocal microscope and reassembled for the 3D reconstruction. Differences in axon size and structure are clearly visible. Contrary to common believe, most axons are not round, but have rather distinct anatomical shapes.

Video 2 shows the cell bodies of the same three neurons. Fluorescent dye was injected into the cell bodies to stain the axons. Video 2 also shows the fine structure of the neuropil area in the stomatogastric ganglion, where the three neurons interact synaptically.

Video 3 slowly scrolls through the different layers, and beautifully shows how 3-dimensional these neurons are.

New PLoS Biology paper

posted Nov 21, 2018, 9:15 PM by Wolfgang Stein

Our newest paper is out in PLoS Biology:

Follmann, R., Goldsmith, C.J. & Stein, W.* (2018). Multimodal sensory information is represented by a combinatorial code in a sensorimotor system. PLoS Biology 16(10), e2004527, epub ahead of print. https://doi.org/10.1371/journal.pbio.2004527

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