Welcome to the crablab at Illinois State University

One of the fundamental questions in Neuroscience is understanding how sensory pathways control neural circuit function to produce adequate behavioral responses in varying environmental conditions. The Stein lab uses experimental and theoretical approaches to study the neuromodulation of sensory pathways and motor circuits, exploiting the advantages of the central pattern generating circuits in the crustacean stomatogastric ganglion. Central pattern generators are sets of neurons that exist in most animals and control rhythmic behaviors, including walking, swimming, breathing and swallowing. In the stomatogastric ganglion, these neurons are easy to record from, they continue to function even if isolated from the animal, and their connectivity is known. Methods used in the lab are manifold, including current and voltage clamp recordings, optical imaging, RNA and DNA extraction, and computer modeling.
The photo above shows a fluorescence staining of the stomatogastric ganglion and its 26 motor neurons. For details click here to read Goldsmith et al., 2014.

Messages

  • Small Circuits and Behavior Meeting in Philadelphia MS student Casey Gährs and PhD student Margaret DeMaegd joined PI Stein at the Small Circuits and Behavior Meeting in Philadelphia this week. We had a great time ...
    Posted Aug 10, 2018, 7:19 AM by Wolfgang Stein
  • We presented at the Meeting of the International Society for Neuroethology At the International Society for Neuroethology Meeting in Brisbane, Australia, PhD student Margaret DeMaegd discusses interactions between different senses via action potentials that backpropagate into sensory dendrites.Below is a ...
    Posted Aug 10, 2018, 7:12 AM by Wolfgang Stein
  • Our newest bookchapter is out Just in time for Margaret DeMaegd's presentation at the Congress of the International Society for Neuroethology: our book chapter in "Sensory Nervous Systems", edited by Thomas Heinbockel, is now ...
    Posted Jul 19, 2018, 1:18 AM by Wolfgang Stein
  • Arthropod Genome Symposium We spent two days at the Arthropod Genome Symposium at the University of Illinois in Urbana-Champaign. The photo shows PI Wolfgang Stein, MS students Casey Gahrs and Abbi Benson ...
    Posted Jun 9, 2018, 8:13 PM by Wolfgang Stein
  • Teaching and Travel Awards Congrats to ALL current student lab members for winning teaching and travel awards at this years Phi Sigma Spring Banquet! Chris Goldsmith won the outstanding PhD student teaching award.Abbi ...
    Posted Apr 28, 2018, 8:10 PM by Wolfgang Stein
Showing posts 1 - 5 of 103. View more »