Welcome to the crablab at Illinois State University

One of the fundamental questions in Neuroscience is understanding how sensory pathways control neural circuit function to produce adequate behavioral responses in varying environmental conditions. The Stein lab uses experimental and theoretical approaches to study the neuromodulation of sensory pathways and motor circuits, exploiting the advantages of the central pattern generating circuits in the crustacean stomatogastric ganglion. Central pattern generators are sets of neurons that exist in most animals and control rhythmic behaviors, including walking, swimming, breathing and swallowing. In the stomatogastric ganglion, these neurons are easy to record from, they continue to function even if isolated from the animal, and their connectivity is known. Methods used in the lab are manifold, including current and voltage clamp recordings, optical imaging, RNA and DNA extraction, and computer modeling.
The photo above shows a fluorescence staining of the stomatogastric ganglion and its 26 motor neurons. For details click here to read Goldsmith et al., 2014.

Messages

  • PhD student Margaret DeMaegd honored in Germany ISU just published a new article about Margaret DeMaegd, PhD student in the Crablab: https://news.illinoisstate.edu/2018/10/doctoral-student-honored-in-germany/Margaret DeMaegd spends most of ...
    Posted Oct 30, 2018, 11:30 AM by Wolfgang Stein
  • New NSF grant Illinois State University news just published a report on our NSF funding. The article can be found here: https://news.illinoisstate.edu/2018/09/stein-earns-495000-nsf-grant-to ...
    Posted Sep 30, 2018, 2:48 PM by Wolfgang Stein
  • Our new eNeuro paper is out! Our newest paper is out in eNeuro - one of the journals of the Society for Neuroscience. The paper is open access and can be viewer here: https://t.co/sXAQvEAp7U ...
    Posted Sep 24, 2018, 6:09 PM by Wolfgang Stein
  • Best poster presentation at the 111th Annual Meeting of the German Zoological Society Congratulations to PhD student Margaret DeMaegd for being awarded one of the best poster presentation awards at the 111th Annual Meeting of the German Zoological Society in Greifswald, Germany. Margaret ...
    Posted Sep 22, 2018, 10:24 AM by Wolfgang Stein
  • Small Circuits and Behavior Meeting in Philadelphia MS student Casey Gährs and PhD student Margaret DeMaegd joined PI Stein at the Small Circuits and Behavior Meeting in Philadelphia this week. We had a great time ...
    Posted Aug 10, 2018, 7:19 AM by Wolfgang Stein
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