Cell Di-Electrophoresis Chamber

Cell Di-Electrophoresis Project Description
Cell Di-Electrophoresis Research Paper



Di-Electrophoresis Team Members

Names of Team members (from Left to Right):

Ze Zhang, Qin Hu, Shawn Maison, Tolga Kaya, Thomas White, and Steve Shapardanis


Not in Picture: 

Adam Bauer

Shawn Maison - Biology, Biotechnology, Anatomy, and Geology Teacher

I am a science teach at both the high school level and collegiate level. Also, I am a naturalist by heart and practice. Studying life on earth and the interactions between the nonliving and living components of earth is what drives current innovation and compasses our future on the planet. While teaching Biological Sciences as a Michigan high school science teacher the curiosity that will drive our future can be seen. As a student who never wanted to stop learning about different happenings of everything that happens here on earth and space I see a common similarity in today’s students as well. I teach biology, anatomy, geology, biotechnology, and physical science. My undergraduate major is in biology, and my Masters degree is in Natural Science. Particularly, I enjoy learning and teaching about the physical aspects of our planet because it determines the future for us all. By educating others about life, and its interactions with our earth, we insure a brighter future for all who live here.

While creating the Di-Electrophoresis chamber and sub-culturing cells for testing I learned an abundance of information and details about the engineering process.  First, working with living cells (osteoblasts) puts fabrication, experimentation, and collaborative
efforts on a timeline.  Second, the engineering process is not a defined start and finish process.  Even though a properly working
di-electrophoresis device was not built the engineering process to design a device, fabricate a prototype, and successfully run tests on the device in multiple ways was used.  Each experiment/test revealed new challenges and new needs in the design, which led to re-fabrication.  Understanding that this is engineering helped me look at these failures as challenges, and new learning experiences, rather than dead ends.  I truly am thankful for the opportunity to take part in, and design, a real engineering project at Central Michigan University.

Molecular Dynamics Study of Conformational Transitions of Poly(N-isopropylacrylamide) Hydrogels on Graphite Oxide Thin Film

Poly(n-isopropylacrylamide) (PNIPAM) as one of the thermo-sensitive polymers, has a coil-to-globule transition as the temperature is raised through the lower critical solution temperature (LCST). The transition has important applications in drug delivery, medical diagnostics, tissue engineering, electrophoresis and separation. Due to the special physical and chemical properties of graphene oxide (GO), the GO film has attracted attention as in next-generation electronic devices such as nonvolatile and thin film transistor. In this project, we are going to make a PNIPAM -GO thin film and study the possible new properties through molecular dynamics simulation. A Linux-based molecular dynamics software GROMACS and a windows-based software COMSOL will be utilized in modeling and simulation of the new material at molecular level and device level. 


Sensor Development for Un-manned Vehicles

Smart vehicles heavily depend on sensor systems; proximity, temperature, humidity, motion, gas sensors, etc. With the proper configuration, an un-manned vehicle could potentially be used for dangerous environment conditions that would otherwise be extremely harmful for humans. While collecting the sensed data is very important, processing the information by interpreting and approximating the results is even crucial. In this particular project, participants will be working on developing a sensor platform using commercial products. Abovementioned sensors will be explored to meet the specifications, which will also be determined by participants. Purchased sensors will be tested individually and a data collection scheme will be developed. Gathered data will be analyzed for different test scenarios and the results will be compared with the theoretical expectations. Basic engineering concepts will be revisited such as units and conversions, data regression and curve fitting, electrical properties of materials, current and voltage laws, and basic circuit topologies. Participants will also have a chance to fabricate their own printed circuit boards where they will place their individual circuit components. This part of the project will also introduce basic Chemistry concepts such as solutions and concentration, acids and bases, and waste disposal.