First, let's do a few exercises together.
If you want more of this kind of practice, you can also try Mouserobics.
Now it's time to explore on your own. Click on the phrase that describes how comfortable you are using a mouse.
Not at all comfortable/Just getting started
Beginning to be comfortable
Getting pretty good
Mouse, schmouse, I got it down
Plus, here are some videos about using a mouse that might be useful - or at least amusing!