Welcome Simon!

posted Aug 29, 2017, 6:13 PM by Yit Heng Chooi

The lab welcomes Simon Keßler who hails from Germany. Simon did holds a BSc and a Master degree in Molecular Biotechnology from Technology University of Munich, Germany. He is starting his PhD in our lab where his project will focus on deciphering and engineering of fungal secondary metabolite biosynthetic pathways.

Prof Yi Tang from UCLA visiting Chooi lab and UWA

posted Jun 27, 2017, 2:53 PM by Yit Heng Chooi

It was a pleasure to host Prof Yi Tang's visit to our lab at UWA last week. Prof Tang gave a wonderful talk at the Bayliss Seminar Series at the School of Molecular Sciences and our group had some very stimulating discussions with him. Look forward to continuing successful collaboration in the future.

Cytotoxic sesquiterpenes uncovered by expression of genes from medicinal mushroom

posted Jun 12, 2017, 9:52 PM by Yit Heng Chooi

Work by Dr. Yeannie Yap while she was in our lab has been published online today in Microbial Cell Factories. The work describes cytotoxic sesquiterpenes obtained by heterologous expression of sesquiterpene synthase genes from the medicinal Tiger Milk mushroom in yeast. Dr Yap was an Endeavour Awards Research Fellow supported by Australian Awards. She did a large part of the work while she is at ANU and at UWA. The work is a collaboration between Dr Shin-Yee Fung (University Malaya), A/Prof Peter Solomon (Australian National University), A/Prof Keith Stubbs (UWA), Szu-Ting Ng (Ligno-Biotech) and our lab.

Well done Yeannie!

BBQ by the Matilda Bay (belated post)

posted May 21, 2017, 9:40 PM by Yit Heng Chooi

We were lucky to get some good weather early May before winter hits. It was a beautiful day for BBQ and some fun with the LYK (little yellow kayak) by the beautiful Matilda Bay near the UWA campus. 

Research on the light-activated phytotoxin from fungal pathogen featured on the cover of Environmental Microbiology

posted Apr 27, 2017, 7:03 PM by Yit Heng Chooi   [ updated May 15, 2017, 8:21 PM ]

Our research on the light-activated phytotoxin elsinochrome from the wheat pathogen P. nodorum has been featured on the cover of the special issue of the journal Environmental Microbiology with the focus topic on "Pathogen and Antibiotic Resistance Ecology". The cover artist is Dr Mariano Jordi Muria-Gonzalez, one of the co-authors of the paper

A biosynthetically talented novel Aspergillus species endemic to Australia

posted Apr 5, 2017, 7:04 PM by Yit Heng Chooi

Collaborative work with CSIRO (Dr John Pitt et al.), Macquarie University (Dr Andrew Piggot), Microbial Screening Technologies (Dr Ern Lacey et al.) and Technology University of Denmark (Dr Lene Lange et al.) is now published online in PLoS ONE. The study describes a biosynthetically talented novel fungal species Aspergillus hancockii, which is endemic to Australia.

PNAS: Novel Biosynthetic Mechanisms involved in the Making of a 60 yo Antibiotic

posted Apr 4, 2017, 6:52 AM by Yit Heng Chooi   [ updated Apr 4, 2017, 6:53 AM ]

Collaborative work with Prof Delin You and his team at the State Key Laboratory of Microbial Metabolism, Shanghai Jiao-Tong University is published in PNAS today! 
See the article here.  The study revealed a novel biosynthetic gene ensemble is involved in the biosynthesis of an important pyrrolidine-containing protein synthesis inhibitor anisomycin, which was isolated over 60 years ago from Streptomyces.  

Welcome Indra!

posted Apr 2, 2017, 6:05 PM by Yit Heng Chooi   [ updated Apr 2, 2017, 6:06 PM ]

The lab welcomes Indra Roux who hails from Argentina. Indra holds a Licenciate Degree in Biotechnology from National University of Quilmes, Buenos Aires. She is starting her PhD in our lab where her project will focus on developing novel synthetic biology tools to advance secondary metabolite biosynthesis in fungi.

Congratulations to Cameron Gilchrist!

posted Feb 9, 2017, 10:47 PM by Yit Heng Chooi   [ updated Feb 9, 2017, 10:48 PM ]

Congratulations to Cameron for receiving an Australian Research Training Program Scholarship for pursuing a Ph.D. in Chooi lab. Cameron was an Honours student in the Chooi lab and he graduated with an H1 last year. Starting March, Cameron will be working on the functional genomics/bioinformatics of fungal secondary metabolism. He will co-supervised by Dr. Josh Mylne.

Honorary Raine/Robson Fellow

posted Dec 11, 2016, 9:28 PM by Yit Heng Chooi   [ updated Dec 11, 2016, 9:29 PM ]

Dr. Chooi was named the 2017 Honorary Raine/Robson Fellow by the Raine Medical Research Foundation. For more details, please see

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