Week 6: Binding, Kinetics, and Catalysis

Lectures 11&12: Kinetics and Catalysis

1. First order reactions
   1. Solution
   2. Half-life
   3. Units
2. Second order reactions
   1. Solutions for limiting cases
      1. Equal initial amounts
      2. One species in excess
   2. Half-life
   3. Units
   4. Symmetric reactions
3. Approach to equilibrium for reversible reaction
4. Enzyme catalysis
   1. Transition state theory description
   2. Michaelis-Menten Scheme
   3. Derivation of quasi-steady state solution
   4. Analysis of the hyperbolic saturation curve
   5. Conditions for validity of the quasi-steady state assumption

Readings

• Cornish-Bowden, Chapter 2. (optional) (link)

Notes

• (pdf)